Heparanase, a potential regulator of cell–matrix interactions

Functions of Cell Surface Heparan Sulfate Proteoglycans

1999 • 2,660 citations

Proteoglycans: Structures And Interactions

1991 • 1,596 citations

Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis

1999 • 788 citations

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

1999 • 516 citations

Cell surface heparan sulfate proteoglycans.

1992 • 476 citations

Heparan sulfate: a piece of information

1996 • 441 citations

Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity.

1999 • 398 citations

Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?

1997 • 392 citations

Human Heparanase

1999 • 297 citations

Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation

2000 • 267 citations

Substrate Specificity of Heparanases from Human Hepatoma and Platelets

1998 • 259 citations

Role of heparan sulfate in immune system-blood vessel interactions

1993 • 200 citations

Processing of the Human Heparanase Precursor and Evidence That the Active Enzyme Is a Heterodimer

1999 • 200 citations

Cloning and Functional Expression of a Human Heparanase Gene

1999 • 199 citations

Human platelet heparanase: purification, characterization and catalytic activity

1998 • 191 citations

Purification and properties of human platelet heparitinase.

1982 • 154 citations

Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T cell adhesion molecule, depending on the local pH.

1995 • 115 citations

Heparan sulphate

1997 • 114 citations

CXC Chemokines Connective Tissue Activating Peptide-III and Neutrophil Activating Peptide-2 are Heparin/Heparan Sulfate-degrading Enzymes

1995 • 103 citations

Heparanase expression in invasive trophoblasts and acute vascular damage

2000 • 97 citations

Modulation of macrophage and B cell function by glycosaminoglycans

1999 • 82 citations

A rapid quantitative assay for the detection of mammalian heparanase activity

1997 • 82 citations

Regulation of platelet heparanase during inflammation: Role of pH and proteinases

1998 • 81 citations

Turnover of Heparan Sulfate Depends on 2-O-Sulfation of Uronic Acids

1997 • 73 citations

Mucin and proteoglycan functions in embryo implantation

1998 • 70 citations

Purification and characterization of placental heparanase and its expression by cultured cytotrophoblasts

1996 • 61 citations

Heparanase and a Synthetic Peptide of Heparan Sulfate-interacting Protein Recognize Common Sites on Cell Surface and Extracellular Matrix Heparan Sulfate

1997 • 48 citations

Evidence that platelet and tumour heparanases are similar enzymes

1999 • 35 citations

Comparison of the heparanase enzymes from mouse melanoma cells, mouse macrophages, and human platelets

1996 • 20 citations

Partial sequence of human platelet heparitinase and evidence of its ability to polymerize

1999 • 16 citations

Evidence that platelet and tumour heparanases are similar enzymes

1999 • 13 citations