Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade enhances incidence and severity of experimental autoimmune neuritis in resistant mice

Enhancement of Antitumor Immunity by CTLA-4 Blockade

1996 • 3,585 citations

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1995 • 2,842 citations

ALLERGIC NEURITIS: AN EXPERIMENTAL DISEASE OF RABBITS INDUCED BY THE INJECTION OF PERIPHERAL NERVOUS TISSUE AND ADJUVANTS

1955 • 570 citations

CTLA-4: a negative regulator of autoimmune disease.

1996 • 382 citations

Engagement of Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Induces Transforming Growth Factor β (TGF-β) Production by Murine CD4+ T Cells

1998 • 359 citations

Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Regulates the Unfolding of Autoimmune Diabetes

1998 • 295 citations

CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis.

1996 • 232 citations

CTLA-4 and T cell activation

1999 • 209 citations

Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats

1990 • 207 citations

Identification of the neuritogen for experimental allergic neuritis

1979 • 188 citations

CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice.

1997 • 187 citations

CTLA-4 Regulates Tolerance Induction and T Cell Differentiation In Vivo

1998 • 174 citations

CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production.

1992 • 153 citations

The Role of CTLA-4 in Regulating Th2 Differentiation

1999 • 148 citations

P0 myelin protein produces experimental allergic neuritis in Lewis rats

1987 • 127 citations

Protective Immunity to Nematode Infection Is Induced by CTLA-4 Blockade

1997 • 113 citations

Cytokine Dichotomy in Peripheral Nervous System Influences the Outcome of Experimental Allergic Neuritis: Dynamics of mRNA Expression for IL-1β, IL-6, IL-10, IL-12, TNF-α, TNF-β, and Cytolysin

1997 • 89 citations

Recombinant IL-4 aggravates experimental autoimmune uveoretinitis in rats.

1996 • 80 citations

Experimental Allergic Neuritis in the Lewis Rat

1979 • 78 citations

Expression of B7 Molecules in Recipient, Not Donor, Mice Determines the Survival of Cardiac Allografts

1999 • 67 citations

T helper type 2 like cytokine responses to peptides from P0 and P2 myelin proteins during the recovery phase of Guillain-Barré syndrome

1997 • 51 citations

Molecular mimicry and the autoimmune response to the peripheral nerve myelin PO glycoprotein

1992 • 50 citations

Pathogenesis of inflammatory demyelination

1995 • 41 citations

P0 protein peptide 180-199 together with pertussis toxin induces experimental autoimmune neuritis in resistant C57BL/6 mice

2000 • 41 citations

Experimental allergic neuritis induced in SJL mice by bovine P2

1985 • 25 citations

Dynamics of mRNA expression of interferon‐γ, interleukin 4 and transforming growth factor β1 in sciatic nerves and lymphoid organs in experimental allergic neuritis

1996 • 19 citations

Induction of experimental autoimmune neuritis in CD4−8− C57BL/6J mice

1999 • 12 citations

Blockade of CD28/B7 Interaction Suppresses Allergic Eosinophilic Inflammation in Mice

1998 • 6 citations