The role of nucleus accumbens dopamine in the neurochemical and behavioral effects of phencyclidine: a microdialysis and behavioral study

Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats

1989 • 562 citations

Autoradiographic localization of sigma receptor binding sites in guinea pig and rat central nervous system with (+)3H-3-(3-hydroxyphenyl)-N-(1- propyl)piperidine

1986 • 385 citations

Specific [3H]phencyclidine binding in rat central nervous system.

1979 • 382 citations

Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotypes behavior and ataxia in rats

1979 • 236 citations

Effects of phencyclidine on [3H]catecholamine and [3H]serotonin uptake in synaptosomal preparations from rat brain

1977 • 214 citations

Phencyclidine and psychotomimetic sigma opiates: recent insights into their biochemical and physiological sites of action

1988 • 189 citations

The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity

1984 • 181 citations

The effects of phencyclidine on the uptake of 3H-catecholamines by rat striatal and hypothalamic synaptosomes

1976 • 161 citations

Non-competitive antagonists are potent activators of ventral tegmental A10 dopamine neurons

1990 • 157 citations

Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response

1987 • 133 citations

Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.

1987 • 125 citations

Drug Effects on Agonistic Behavior

1979 • 115 citations

Continuous amphetamine intoxication: an animal model of the acute psychotic episode

1983 • 113 citations

Inhibition by phencyclidine of excitatory amino acid-stimulated release of neurotransmitter in the nucleus accumbens

1987 • 91 citations

Phencyclidine-induced rotational behavior in rats with nigrostriatal lesions and its modulation by dopaminergic and cholinergic agents

1976 • 89 citations

Disruption of primate social behavior by d-amphetamine and cocaine: Differential antagonism by antipsychotics

1982 • 88 citations

Similar dopamine-releasing effects of phencyclidine and nonamphetamine stimulants in striatal slices.

1982 • 85 citations

The effect of phencyclidine on dopamine synthesis and metabolism in rat striatum

1980 • 85 citations

Increases in extracellular dopamine levels and locomotor activity after direct infusion of phencyclidine into the nucleus accumbens

1992 • 85 citations

Phencyclidine (PCP): A Review and Perspectives

1982 • 83 citations

Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors.

1987 • 68 citations

Phencyclidine-induced locomotor activity in the rat is blocked by 6-hydroxydopamine lesion of the nucleus accumbens: Comparisons to other psychomotor stimulants

1983 • 68 citations

Phencyclidine binding sites in the nucleus accumbens and phencyclidine-induced hyperactivity are decreased following lesions of the mesolimbic dopamine system

1985 • 65 citations

Neuropharmacological studies of phencyclidine (PCP)-induced behavioral stimulation in mice

1980 • 57 citations

Phencyclidine as an indirect dopamine agonist [proceedings].

1980 • 55 citations

Phencyclidine: An Overview

1977 • 49 citations

Behavioral activation in rats increases striatal dopamine metabolism measured by dialysis perfusion

1989 • 48 citations

Effects of chronic d-amphetamine on social behavior of the rat: Implications for an animal model of paranoid schizophrenia

1976 • 47 citations

Stages of constant amphetamine intoxication: Delayed appearance of abnormal social behaviors in rat colonies

1978 • 45 citations

Phencyclidine increases extracellular dopamine metabolites in rat medial frontal cortex as measured by in vivo dialysis

1990 • 44 citations

Effects of phencyclidine and methylphenidate on d-amphetamine-induced behaviors in reserpine pretreated rats

1980 • 43 citations

Effects of phencyclidine on synaptosomal dopamine continuously appearing from phenylalanine: Sensitivity to reserpine

1981 • 31 citations

Effects of phencyclidine on extracellular levels of dopamine, dihydroxyphenylacetic acid and homovanillic acid in conscious and anesthetized rats

1990 • 30 citations

Neurobiology of phencyclidine--an update.

1978 • 22 citations

Stimulation of synaptosomal tyrosine hydroxylation by phencyclidine in vitro

1981 • 21 citations

The effect of phencyclidine on dopamine metabolism in the mouse brain

1981 • 20 citations

Social withdrawal following amphetamine administration to marmosets

1989 • 19 citations

Effects of phencyclidine on the release and synthesis of newly formed dopamine

1983 • 19 citations