Messenger RNA Transport and HIV rev Regulation

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation

1986 • 755 citations

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1990 • 723 citations

Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression

1989 • 574 citations

Regulation by HIV Rev depends upon recognition of splice sites

1989 • 517 citations

Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA

1987 • 508 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

1989 • 434 citations

The "Spliceosome": Yeast Pre-Messenger RNA Associates with a 40 S Complex in a Splicing-Dependent Reaction

1985 • 421 citations

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1989 • 417 citations

Sequence-specific RNA binding by the HIV-1 Rev protein

1989 • 384 citations

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns.

1989 • 349 citations

A protein associated with small nuclear ribonucleoprotein particles recognizes the 3′ splice site of premessenger RNA

1986 • 283 citations

A protein that specifically recognizes the 3′ splice site of mammalian pre-mRNA introns is associated with a small nuclear ribonucleoprotein

1986 • 274 citations

RNA binding specificity of hnRNP proteins: a subset bind to the 3′ end of introns.

1988 • 251 citations

Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles.

1990 • 225 citations

The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism.

1989 • 169 citations

Regulation of Rous sarcoma virus RNA splicing and stability.

1988 • 137 citations

The sphere organelle contains small nuclear ribonucleoproteins.

1989 • 86 citations

Autonomous splicing and complementation of in vivo-assembled spliceosomes.

1989 • 78 citations

Localization of an Acetylcholine Receptor Intron to the Nuclear Membrane

1990 • 44 citations

Transforming viruses spontaneously arise from nontransforming reticuloendotheliosis virus strain T-derived viruses as a result of increased accumulation of spliced viral RNA

1988 • 14 citations