Lack of Association of Polymorphisms of the Angiotensin Converting Enzyme and Angiotensinogen Genes With Nonfamilial Hypertrophic or Dilated Cardiomyopathy

Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.

1977 • 4,520 citations

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

1990 • 3,809 citations

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

1992 • 1,956 citations

Molecular basis of human hypertension: Role of angiotensinogen

1992 • 1,861 citations

Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

1993 • 1,347 citations

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

1990 • 1,332 citations

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

1992 • 1,280 citations

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

1992 • 1,181 citations

α-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere

1994 • 1,008 citations

Association between a Deletion Polymorphism of the Angiotensin-Converting-Enzyme Gene and Left Ventricular Hypertrophy

1994 • 757 citations

Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

1988 • 741 citations

Characteristics and Prognostic Implications of Myosin Missense Mutations in Familial Hypertrophic Cardiomyopathy

1992 • 732 citations

The Frequency of Familial Dilated Cardiomyopathy in a Series of Patients with Idiopathic Dilated Cardiomyopathy

1992 • 704 citations

Linkage of the Angiotensinogen Gene to Essential Hypertension

1994 • 579 citations

X-linked dilated cardiomyopathy. Molecular genetic evidence of linkage to the Duchenne muscular dystrophy (dystrophin) gene at the Xp21 locus.

1993 • 513 citations

A molecular variant of angiotensinogen associated with preeclampsia

1993 • 505 citations

Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene

1991 • 435 citations

Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy

1993 • 426 citations

Deletion of the Dystrophin Muscle-Promoter Region Associated with X-Linked Dilated Cardiomyopathy

1993 • 413 citations

Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death

1993 • 412 citations

Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease

1995 • 310 citations

Recent Advances in the Molecular Genetics of Hypertrophic Cardiomyopathy

1995 • 218 citations

Angiotensin-I Converting Enzyme Genotypes and Left Ventricular Hypertrophy in Patients With Hypertrophic Cardiomyopathy

1995 • 212 citations

Rapid detection of the hypertension-associated Met²³⁵→ Thr allele of the human angiotensinogen gene

1993 • 208 citations

Mapping a cardiomyopathy locus to chromosome 3p22-p25.

1996 • 193 citations

Molecular Basis of Familial Cardiomyopathies

1995 • 188 citations

A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1–1q1

1994 • 183 citations

Study of Left Ventricular Geometry and Function by B-Scan Ultrasonography in Patients with and without Asynergy

1974 • 182 citations

Inherited idiopathic dilated cardiomyopathy with multiple deletions of mitochondrial DNA

1992 • 151 citations

Localization of a Gene Responsible for Familial Dilated Cardiomyopathy to Chromosome 1q32

1995 • 148 citations

Enhanced Predictability of Myocardial Infarction in Japanese by Combined Genotype Analysis

1995 • 109 citations

Lack of association between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and idiopathic dilated cardiomyopathy

1995 • 70 citations

Angiotensin-Converting Enzyme and Heart Chymase gene Polymorphisms in Hypertrophic Cardiomyopathy**This study was supported by a grant-in-aid from the Bundesministerium für Bildung und Forschung and the European commission grant (ERBCHBGCT 940725.

1996 • 68 citations

Angiotensin-converting enzyme gene polymorphism in Japanese patients with hypertrophic cardiomyopathy

1995 • 68 citations

Rapid detection and prevalence of the variants of the angiotensinogen gene in patients with essential hypertension

1995 • 58 citations

Lack of association between insertion/deletion polymorphism of the angiotensin-converting enzyme gene and end-stage heart failure due to ischemic or idiopathic dilated cardiomyopathy in the chinese

1996 • 45 citations

Renin-angiotensin system in failing heart

1995 • 31 citations