Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

2017 • 4,003 citations

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 • 2,516 citations

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1976 • 2,458 citations

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

1991 • 1,950 citations

Induction of Interleukin 10–Producing, Nonproliferating Cd4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells

2000 • 1,577 citations

Foxp3⁺CD25⁺CD4⁺ natural regulatory T cells in dominant self‐tolerance and autoimmune disease

2006 • 1,535 citations

NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells

2002 • 1,392 citations

Natural versus adaptive regulatory T cells

2003 • 1,363 citations

Induction of tolerance by IL-10-treated dendritic cells.

1997 • 1,263 citations

In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

2002 • 1,163 citations

Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans

2006 • 1,156 citations

Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

2001 • 1,126 citations

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

1995 • 868 citations

Tolerance, not immunity, crucially depends on IL-2

2004 • 826 citations

IMMUNOPHARMACOLOGY OF RAPAMYCIN

1996 • 651 citations

Interleukin 2 Signaling Is Required for CD4+ Regulatory T Cell Function

2002 • 630 citations

IFN-α and IL-10 Induce the Differentiation of Human Type 1 T Regulatory Cells

2001 • 610 citations

Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells

2004 • 482 citations

Immune suppression in cancer: Effects on immune cells, mechanisms and future therapeutic intervention

2005 • 474 citations

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

1994 • 413 citations

The Interleukin-2 Receptor γ Chain: Its Role in the Multiple Cytokine Receptor Complexes and T Cell Development in XSCID

1996 • 411 citations

Interleukin-10 and the immune response against cancer: a counterpoint

2005 • 393 citations

Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells

2004 • 379 citations

Selective Survival of Naturally Occurring Human CD4+CD25+Foxp3+ Regulatory T Cells Cultured with Rapamycin

2007 • 335 citations

Tr1 cells: From discovery to their clinical application

2006 • 272 citations

Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer

2005 • 271 citations

Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines.

1989 • 254 citations

IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2

1995 • 221 citations

IL-4 is a differentiation factor for transforming growth factor-β secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis

1998 • 218 citations

Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines

2002 • 194 citations

Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance.

2006 • 175 citations

Rapamycin and Interleukin-10 Treatment Induces T Regulatory Type 1 Cells That Mediate Antigen-Specific Transplantation Tolerance

2006 • 168 citations

Phenotypic and Functional Differences Between Human CD4+CD25+ and Type 1 Regulatory T Cells

2005 • 87 citations

Regulatory cells and human cancer

2005 • 82 citations

Human CD4+CD25+ regulatory T cells and infectious tolerance.

2004 • 69 citations

Transforming growth factor‐β and T‐cell‐mediated immunoregulation in the control of autoimmune diabetes

2006 • 61 citations

Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation

2005 • 58 citations

Commitment of individual Th1-like lymphocytes to expression of IFN-gamma versus IL-4 and IL-10: selective induction of IL-10 by sequential stimulation of naive Th cells with IL-12 and IL-4.

1998 • 54 citations

Commitment of Individual Th1-Like Lymphocytes to Expression of IFN-γ Versus IL-4 and IL-10: Selective Induction of IL-10 by Sequential Stimulation of Naive Th Cells with IL-12 and IL-4

1998 • 41 citations

Deleted Work

1955 • 0 citations