IL-8 as a circulating cytokine: induction by recombinant tumour necrosis factor-alpha

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

1989 • 1,993 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

1988 • 990 citations

TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria

1990 • 861 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.

1989 • 651 citations

Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.

1988 • 603 citations

Endothelial Interleukin-8: A Novel Inhibitor of Leukocyte-Endothelial Interactions

1989 • 459 citations

Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice.

1990 • 343 citations

IL-8 in septic shock, endotoxemia, and after IL-1 administration.

1991 • 313 citations

The role of IFN-gamma in the pathology of experimental endotoxemia.

1990 • 257 citations

Enhanced production of neutrophil-activating peptide-1/interleukin-8 in rheumatoid arthritis.

1991 • 256 citations

Serum cachectin/tumor necrosis factor in critically ill patients with burns correlates with infection and mortality.

1990 • 217 citations

Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes.

1990 • 211 citations

Kinetics of TNF, IL-6, and IL-8 gene expression in LPS-stimulated human whole blood

1991 • 207 citations

In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes.

1989 • 198 citations

Human neutrophils exhibit disparate chemotactic factor gene expression

1990 • 114 citations

Human recombinant tumor necrosis factor alpha infusion mimics endotoxemia in awake sheep

1989 • 90 citations

Detection of neutrophil-activating peptide NAP/IL-8 and NAP/IL-8 mRNA in human recombinant IL-1 alpha- and human recombinant tumor necrosis factor-alpha-stimulated human dermal fibroblasts. An immunocytochemical and fluorescent in situ hybridization study.

1990 • 66 citations

Tumor necrosis factor-alpha, interleukin-8 and chemotactic cytokines.

1990 • 40 citations

Effects of in vivo 'priming' on endotoxin-induced hypotension and tissue injury. The role of PAF and tumor necrosis factor.

1990 • 30 citations

Dose-dependent increase in plasma interleukin-6 after recombinant tumour necrosis factor infusion in humans

1990 • 25 citations

Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

1989 • 15 citations

Phase I study of recombinant human tumor necrosis factor-alpha in patients with advanced malignancies.

1988 • 9 citations