Flow Cytometric Study of T Cell Development in NOD Mice Reveals a Deficiency in αβTCR+CD4−CD8−Thymocytes

Breeding of a Non-Obese, Diabetic Strain of Mice

1980 • 1,255 citations

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

1994 • 862 citations

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1987 • 576 citations

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.

1993 • 510 citations

Role of NK1.1 ⁺ T Cells in a T _H 2 Response and in Immunoglobulin E Production

1995 • 508 citations

Selective Events in T Cell Development

1994 • 486 citations

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice.

1988 • 455 citations

Control points in early T-cell development

1993 • 429 citations

Early quantitative and functional deficiency of NK1⁺‐like thymocytes in the NOD mouse

1996 • 359 citations

Mouse NK1+ T cells

1995 • 292 citations

Association Between αβTCR+CD4−CD8− T-Cell Deficiency and IDDM in NOD/Lt Mice

1997 • 258 citations

Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4.

1995 • 237 citations

Thymic selection: a matter of life and death

1992 • 184 citations

Cytokine production by mature and immature CD4-CD8- T cells. Alpha beta-T cell receptor+ CD4-CD8- T cells produce IL-4.

1992 • 167 citations

Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target.

1994 • 144 citations

<b>The inhibitory effect of neonatal thymectomy on the incidence of insulitis in non-obese diabetes (NOD) </b><b>mice </b>

1985 • 103 citations

Cellular aspects of early T-cell development

1992 • 91 citations

IL-7 reverses NK1⁺ Tcell-defective IL-4 production in the non-obese diabetic mouse

1996 • 69 citations

Studies on the thymus in nonobese diabetic mouse. I. Changes in the microenvironmental compartments.

1991 • 51 citations

MHC class I-selected CD4-CD8-TCR-alpha beta+ T cells are a potential source of IL-4 during primary immune response.

1995 • 34 citations

Thymic epithelial defects and predisposition to autoimmune disease in BB rats.

1994 • 32 citations

Multiple Routes for Late Intrathymic Precursors to Generate CD4+CD8+ Thymocytes

1992 • 22 citations

Studies on the thymus of non-obese diabetic (NOD) mice: effect of transgene expression.

1994 • 21 citations

Thymus reticulum of autoimmune mice. 3. Ultrastructural study of NOD (non-obese diabetic) mouse thymus.

1991 • 17 citations

Lymphocyte Subsets in Thymus and Peripheral Lymphoid Tissues of Aging and Diabetic Nod Mice

1994 • 16 citations

Age-related changes in Tγδ cells of NOD mice

1995 • 16 citations

Characterization of Giant Perivascular Spaces in the Thymus of the Nonobese Diabetic Mouse

1994 • 2 citations