Isopenicillin N synthetase of Penicillium chrysogenum, an enzyme that converts delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Induced Fusion of Fungal Protoplasts following Treatment with Polyethylene Glycol

1976 • 152 citations

Cell-free conversion of δ-(<scp>l</scp>-α-aminoadipyl)-<scp>l</scp>-cysteinyl-<scp>d</scp>-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremonium

1979 • 104 citations

A Pure Enzyme Catalyzing Penicillin Biosynthesis

1984 • 92 citations

Carbon catabolite repression of penicillin biosynthesis by Penicillium chrysogenum.

1984 • 77 citations

Inhibition and repression of homocitrate synthase by lysine in Penicillium chrysogenum

1980 • 75 citations

Carbon catabolite regulation of the conversion of penicillin N into cephalosporin C.

1983 • 72 citations

Cyclization of .DELTA.-(L-.ALPHA.-aminoadipyl)-L-cysteinyl-D-valine to penicillins by cell-free extracts of Streptomyces clavuligerus.

1982 • 70 citations

Studies on the ring-cyclization and ring-expansion enzymes of β-lactam biosynthesis in Cephalosporium acremonium

1983 • 66 citations

Lysine Regulation of Penicillin Biosynthesis in Low-producing and Industrial Strains of Penicillium chrysogenum

1979 • 58 citations

[34] Preparative acrylamide gel electrophoresis: Continuous and disc techniques

1971 • 55 citations

Cell-free cyclization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N

1980 • 53 citations

Biosynthesis of β-Lactam Antibiotics

1983 • 47 citations

Presence of δ-( <scp>l</scp> -α-Aminoadipyl)- <scp>l</scp> -Cysteinyl- <scp>d</scp> -Valine in Fermentations of Penicillium chrysogenum

1975 • 34 citations

High performance liquid chromatographic assay of cyclization activity in cell-free systems from Streptomyces clavuligerus.

1982 • 26 citations

Regulation of Biosynthesis of β-Lactam Antibiotics

1983 • 25 citations

The absolute configuration of the amino acids in δ-(α-aminoadipyl)cysteinylvaline from Penicillium chrysogenum

1976 • 22 citations

Strain Improvement and Preservation of β-Lactam-Producing Microorganisms

1983 • 21 citations

Studies on the biosynthesis of isopenicillin N with a cell-free preparation of Penicillium chrysogenum.

1980 • 19 citations

On the proposed intermediacy of β-hydroxyvaline- and thiazepinone-containing peptides in penicillin biosynthesis

1981 • 12 citations

The stereochemistry of cyclisation of n--butyldihydrocinnamamide to a β-lactam

1982 • 8 citations

The fermentation, isolation and characterization of a macromolecular peptide antibiotic: An-1.

1984 • 8 citations

PENICILLIN PRODUCTION BY RECOMBINANT STRAINS OF Penicillium chrysogenum OBTAINED BY FUSION OF PROTOPLASTS

1981 • 1 citations