Apolipoprotein E Deficiency Leads to Cutaneous Foam Cell Formation in Mice

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1992 • 2,216 citations

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

1992 • 2,189 citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1993 • 1,267 citations

Human apolipoprotein E. The complete amino acid sequence.

1982 • 731 citations

Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice.

1994 • 704 citations

Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit) *1Incidence and development of atherosclerosis and xanthoma

1980 • 540 citations

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.

1985 • 500 citations

Membrane Structures in Normal and Essential Fatty Acid-Deficient Stratum Corneum: Characterization by Ruthenium Tetroxide Staining and X-Ray Diffraction

1991 • 296 citations

Type III Hyperlipoproteinemia Associated with Apolipoprotein E Deficiency

1981 • 272 citations

Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption.

1994 • 235 citations

De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements.

1985 • 208 citations

Xanthomas and hyperlipidemias

1985 • 162 citations

Systemic distribution of apolipoprotein E secreted by grafts of epidermal keratinocytes: implications for epidermal function and gene therapy.

1989 • 131 citations

Dermal, subcutaneous, and tendon xanthomas: Diagnostic markers for specific lipoprotein disorders

1988 • 118 citations

Preventive effect of pravastatin sodium, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on coronary atherosclerosis and xanthoma in WHHL rabbits

1988 • 103 citations

Type III hyperlipoproteinemia: recent insights into the genetic defect of familial dysbetalipoproteinemia.

1984 • 93 citations

Effect of cutaneous permeability barrier disruption on HMG-CoA reductase, LDL receptor, and apolipoprotein E mRNA levels in the epidermis of hairless mice.

1992 • 55 citations

Synthesis and Secretion of Apolipoprotein E by Cultured Human Keratinocytes

1989 • 45 citations