The Merck Gene Index project

Serial Analysis of Gene Expression

1995 • 3,659 citations

Hudson et al.

1977 • 2,560 citations

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1995 • 2,028 citations

The I.M.A.G.E. Consortium: An Integrated Molecular Analysis of Genomes and Their Expression

1996 • 1,132 citations

Variations on a Theme: Cataloging Human DNA Sequence Variation

1997 • 1,064 citations

A gene map of the human genome.

1996 • 986 citations

Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.

1995 • 804 citations

An STS-Based Map of the Human Genome

1995 • 782 citations

Characterization of the Structure and Function of a New Mitogen-activated Protein Kinase (p38β)

1996 • 744 citations

A Gene Map of the Human Genome

1996 • 737 citations

A Physical Map of 30,000 Human Genes

1998 • 723 citations

Normalization and subtraction: two approaches to facilitate gene discovery.

1996 • 542 citations

Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression

1992 • 528 citations

Direct Analysis and Identification of Proteins in Mixtures by LC/MS/MS and Database Searching at the Low-Femtomole Level

1997 • 516 citations

Generation and analysis of 280,000 human expressed sequence tags.

1996 • 474 citations

The Role of the Genome Project in Determining Gene Function: Insights from Model Organisms

1996 • 450 citations

Construction and characterization of a normalized cDNA library.

1994 • 411 citations

DNA chips: An array of possibilities

1998 • 406 citations

Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library

1993 • 361 citations

3,400 new expressed sequence tags identify diversity of transcripts in human brain

1993 • 292 citations

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

1997 • 258 citations

Cloning of a novel member of the low-density lipoprotein receptor family

1998 • 217 citations

Isolation and Characterization ofLRP6,a Novel Member of the Low Density Lipoprotein Receptor Gene Family

1998 • 207 citations

DNA chips: analysing sequence by hybridization to oligonucleotides on a large scale

1996 • 202 citations

Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching

1996 • 188 citations

Cloning and characterization of the human homologue of a dystrophin related phosphoprotein found at the Torpedo electric organ post- synaptic membrane

1996 • 128 citations

Toward the development of a gene index to the human genome: an assessment of the nature of high-throughput EST sequence data.

1996 • 124 citations

High-density cDNA filter analysis: a novel approach for large-scale, quantitative analysis of gene expression

1995 • 123 citations

Use of 3' untranslated sequences of human cDNAs for rapid chromosome assignment and conversion to STSs: implications for an expression map of the genome

1991 • 117 citations

The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and Expressed Sequence Tag Databases

1997 • 86 citations

Isolation of Inositol 1,3,4-Trisphosphate 5/6-Kinase, cDNA Cloning, and Expression of the Recombinant Enzyme

1996 • 82 citations

Molecular Cloning and Functional Analysis of a Human cDNA Encoding an Escherichia Coli AlkB Homolog, a Protein Involved in DNA Alkylation Damage Repair

1996 • 77 citations

“Colored” Noise Waveforms and Quadrupole Excitation for the Dynamic Range Expansion of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

1996 • 70 citations

The Merck Gene Index browser: an extensible data integration system for gene finding, gene characterization and EST data mining.

1998 • 37 citations

Identification and cloning of differentially expressed genes

1997 • 34 citations

Ahead of schedule and under budget: the Genome Project passes its fifth birthday.

1995 • 32 citations

Characterization and mapping of three new mammalian ATP-binding transporter genes from an EST database

1995 • 29 citations

Use of the EST Database Resource to Identify and Clone Novel Mono(ADP-Ribosyl)Transferase Gene Family Members

1997 • 14 citations

Simultaneous detection of size and sequence polymorphisms in the transcribed trinucleotide repeat D2S196E (EST00493)

1997 • 12 citations

cDNA expression and human two‐dimensional gel protein databases: Towards integrating DNA and protein information

1996 • 10 citations

The use of expressed sequence tag databases to identify novel human γ-aminobutyric acid type receptor genes

1997 • 1 citations