Effects of Ethanol on the Contractile Function of the Heart: A Review

The Effects of Alcoholism on Skeletal and Cardiac Muscle

1989 • 669 citations

Fluorescent Probes of Cell Signaling

1989 • 649 citations

Arrhythmias and the “Holiday Heart”: Alcoholassociated cardiac rhythm disorders

1978 • 595 citations

Ventricular function in noncardiacs with alcoholic fatty liver: role of ethanol in the production of cardiomyopathy

1969 • 229 citations

The acute metabolic and hemodynamic responses of the left ventricle to ethanol.

1966 • 221 citations

Alcoholic Myopathy in Heart and Skeletal Muscle

1979 • 208 citations

Alcoholic cardiomyopathy. An electron microscopic study

1965 • 198 citations

Effects of ethanol on the chemical and structural properties of biologic membranes.

1985 • 189 citations

The "Holiday Heart": Electrophysiologic Studies of Alcohol Effects in Alcoholics

1983 • 178 citations

Alcohol and the Cardiovascular System

1990 • 170 citations

Ethanol and signal transduction in the liver.

1992 • 157 citations

Ethanol and signal transduction in the liver

1992 • 138 citations

Effect of ethanol on metabolism and function of perfused rat heart

1969 • 132 citations

Echocardiographic abnormalities in chronic alcoholics with and without overt congestive heart failure

1981 • 132 citations

Effects of ethanol on cellular membrane potentials and contractility of isolated rat atrium

1962 • 131 citations

Depression of Myocardial Contractility with Low Doses of Ethanol in Normal Man

1973 • 119 citations

Acute hemodynamic effects of ethanol on normal human volunteers

1969 • 115 citations

Effects of chronic graded ethanol consumption on the metabolism, ultrastructure, and mechanical function of the rat heart

1975 • 114 citations

Cardiac effects of acute ethanol ingestion unmasked by autonomic blockade.

1979 • 109 citations

Myocardial Function and Lipid Metabolism in the Chronic Alcoholic Animal

1974 • 108 citations

Medical Diagnosis and Treatment of Alcoholism

1993 • 105 citations

Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase.

1982 • 103 citations

The heart in chronic alcoholism: a noninvasive study

1980 • 101 citations

Biochemical and contractile properties of heart muscle after prolonged alcohol administration

1976 • 100 citations

Alcoholic cardiomyopathy and sudden cardiac death

1986 • 99 citations

Cellular calcium; A practical approach

1992 • 99 citations

Ethanol acutely and reversibly suppresses excitation-contraction coupling in cardiac myocytes.

1991 • 93 citations

Preclinical cardiomyopathy in chronic alcoholics: A sex difference

1976 • 89 citations

Mechanism of myocardial contractile depression by clinical concentrations of ethanol. A study in ferret papillary muscles.

1990 • 88 citations

The Functional Implications of Acetaldehyde Binding to Cell Constituentsa

1987 • 87 citations

Cardiovascular effects of alcohol.

1989 • 87 citations

Role of phosphatidylethanol in membranes. Effects on membrane fluidity, tolerance to ethanol, and activity of membrane-bound enzymes

1991 • 86 citations

Alcoholic cardiomyopathy

1984 • 84 citations

Myocardial mechanical, biochemical, and structural alterations induced by chronic ethanol ingestion in rats.

1992 • 82 citations

Alcoholic cardiomyopathy

1971 • 81 citations

Acute Effects of Ethanol on Left Ventricular Performance

1974 • 78 citations

Human Blood Acetaldehyde Levels: With Improved Methods, a Clearer Picture Emerges

1983 • 76 citations

Effect of ethanol and acetaldehyde on the (Na+ + K+)-activated adenosine triphosphatase activity of cardiac plasma membranes

1975 • 75 citations

The effects of alcohol on local, neural and humoral cardiovascular regulation

1986 • 71 citations

Adenosine Diphosphate Effect on Contractility of Human Muscle Actomyosin: Inhibition by Ethanol and Acetaldehyde

1975 • 70 citations

Effects of ethanol on calcium binding and calcium uptake by cardiac microsomes

1974 • 69 citations

Effect of whiskey on atrial vulnerability and “holiday heart”

1983 • 66 citations

The effects of chronic ethanol consumption on cardiac function in rats

1982 • 64 citations

Reversibility of mitochondrial and contractile changes in the myocardium after cessation of prolonged ethanol intake

1977 • 63 citations

Progression of myocardial abnormalities in experimental alcoholism

1980 • 61 citations

Electrophysiological effects of ethanol, acetaldehyde, and acetate on cardiac tissues from dog and guinea pig.

1980 • 59 citations

Phospholipase D activity in subcellular membranes of rat ventricular myocardium

1991 • 59 citations

Left ventricular dysfunction of isolated working rat hearts after chronic alcohol consumption

1979 • 58 citations

Depression of cardiac performance by ethanol unmasked during autonomic blockade

1973 • 56 citations

Alcohol-induced cardiac hemodynamic and Ca2+ flux dysfunctions are reversible

1981 • 55 citations

Prevalence of clinically occult cardiomyopathy in chronic alcoholism

1981 • 51 citations

ALCOHOL AND THE HEART

1982 • 51 citations

Ethanol inhibits electrically-induced calcium transients in isolated rat cardiac myocytes

1989 • 49 citations

Left ventricular dysfunction induced by chronic alcohol ingestion in rats

1991 • 42 citations

Alcohol and the cardiovascular system

1987 • 41 citations

Normalization of variables of left ventricular function in patients with alcoholic cardiomyopathy after cessation of excessive alcohol intake: an echocardiographic study

1987 • 41 citations

Effect of ethanol on contraction and relaxation of isolated rat ventricular muscle

1976 • 40 citations

Inhibition of forskolin-activated adenylate cyclase by ethanol and other solvents.

1982 • 40 citations

Preclinical abnormaltiy of left ventricular function in chronic alcoholics.

1977 • 37 citations

Impaired myocardial performance and response to calcium in experimental alcoholic cardiomyopathy

1981 • 37 citations

Acute effects of alcohol, beta blockade, and their combination on left ventricular function and hemodynamics in normal man

1983 • 37 citations

Ethanol increases calcium permeability of heavy sarcoplasmic reticulum of skeletal muscle

1984 • 36 citations

Alcohol intemperance and sudden death.

1987 • 35 citations

Electrocardiographic Abnormalities in Alcoholic Cardiomyopathy

1975 • 35 citations

Effects of ethanol on calcium transport by microsomes phosphorylated by cyclic AMP-dependent protein kinase

1977 • 34 citations

Effects of ethanol on ion transport in muscle membranes.

1982 • 33 citations

The Mechanism of Increase in the ATPase Activity of Sarcoplasmic Reticulum Vesicles Treated with n-Alcohols

1977 • 33 citations

The Harmful Effects of Ethanol on Ion Transport and Cellular Respiration

1985 • 31 citations

Influence of alcohol on peripheral neurotransmitter function.

1982 • 30 citations

Mechanism of Fatty Acid Ethyl Ester Formation and Biological Significance

1991 • 30 citations

Synthesis of subcellular protein fractions in the rat heart in vivo in response to chronic ethanol feeding

1989 • 29 citations

Risk Factors for Sudden Unexpected Cardiac Death in Young Women in Rochester, Minnesota, 1960 Through 1974

1986 • 29 citations

Acute and Chronic Effects of Ethanol on Sinoatrial Electrophysiology in the Rat Heart

1987 • 26 citations

Effect of alcohol on the heart and cardiac metabolism.

1982 • 26 citations

Acute effects of mildly intoxicating levels of alcohol on left ventricular function in conscious dogs.

1990 • 24 citations

Effects of acetaldehyde on the systemic, pulmonary, and regional circulations

1974 • 23 citations

Spectrum of heart muscle abnormalities related to alcoholism

1980 • 23 citations

Inhibition by alcohols, halothane and chloroform of the Ca current in single frog ventricular cells

1990 • 23 citations

Alcohol and the heart: theoretical considerations.

1982 • 22 citations

Cardiac dysfunction in unselected chronic alcoholic patients: Noninvasive screening by systolic time intervals

1974 • 21 citations

Excitation-contraction coupling in rat myocardium: alterations with long term ethanol consumption

1986 • 21 citations

The effect of ethanol and acetaldehyde on Na pump function in cultured rat heart cells1

1987 • 21 citations

Reversibility of chronic alcohol cardiac depression: ³¹P magnetic resonance spectroscopy in hamsters

1989 • 20 citations

Effects of ethanol and acetaldehyde on the isolated, blood-perfused canine atrium.

1979 • 20 citations

Beta-adrenergic receptors in chronic alcoholic rat hearts

1982 • 20 citations

Vulnerability to cardiac disease.

1991 • 18 citations

Regional circulatory responses to alcohol and its congeners.

1982 • 18 citations

Experimental models for studying the effects of ethanol on the myocardium

1987 • 18 citations

Increased Ventricular Vulnerability in a Chronic Ethanol Model Despite Reduced Electrophysiologic Responses to Catecholamines

1991 • 17 citations

Effects of ethanol on calcium and potassium currents in single bullfrog atrial cells.

1984 • 16 citations

Chronic Alcohol Ingestion Alters the Calcium Permeability of Sarcoplasmic Reticulum of Rat Skeletal Muscle

1985 • 16 citations

Effects of Ethanol and Cocaine on Electrically Triggered Calcium Transients in Cardiac Muscle Cells^a

1991 • 15 citations

A Moderate Concentration of Ethanol Alters Cellular Membrane Potentials and Decreases Contractile Force of Human Fetal Heart

1989 • 11 citations

Suppression of ethanol-induced cardiac hypertrophy by β-adrenoceptor blockade

1990 • 8 citations

Actions and interactions of calcium modulators and ethanol on rat atrial membrane potentials

1990 • 8 citations

Tolerance to Ethanol and Cross‐Tolerance to Pentobarbital by Isolated Hearts from Chronic Alcoholic Rats

1988 • 7 citations

Mitochondrial Respiration after Cardiac Perfusion with Ethanol or Acetaldehyde

1984 • 7 citations

Alcohol-induced alterations in calcium handling

1988 • 7 citations

Cardiac electrophysiology in rats drinking moderate amounts of ethanol.

1987 • 7 citations

Ethanol inhibition of spontaneous calcium release from isolated sarcoplasmic reticulum.

1989 • 5 citations

Depression of contraction and the calcium transient in single cardiomyocytes with acute ethanol exposure

1992 • 2 citations