Decrease in GABA immunoreactivity and alteration of GABA metabolism after kindling in the rat hippocampus

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Decreased Hippocampal Inhibition and a Selective Loss of Interneurons in Experimental Epilepsy

1987 • 1,077 citations

Immunocytochemistry: 2nd edn

1980 • 880 citations

Different populations of GABAergic neurons in the visual cortex and hippocampus of cat contain somatostatin- or cholecystokinin- immunoreactive material

1984 • 733 citations

Antibodies against gamma-aminobutyric acid: specificity studies and immunocytochemical results.

1984 • 332 citations

GABAergic neurons containing CCK‐8‐like and/or VIP‐like immunoreactivities in the rat hippocampus and dentate gyrus

1985 • 325 citations

Antisera to gamma-aminobutyric acid. II. Immunocytochemical application to the central nervous system.

1985 • 294 citations

Does the Engram of Kindling Model the Engram of Normal Long Term Memory?

1975 • 220 citations

Abnormal neuronal excitability in hippocampal slices from kindled rats

1985 • 206 citations

The kindling model of epilepsy: a critical review.

1985 • 186 citations

PROPERTIES OF BRAIN <scp>l</scp>‐GLUTAMATE DECARBOXYLASE: INHIBITION STUDIES¹

1974 • 186 citations

Kindling mechanisms: Current progress on an experimental epilepsy model

1986 • 179 citations

Intracellular calcium accumulation in rat hippocampus during seizures induced by bicuculline orl-allylglycine

1983 • 168 citations

Kindling model of epilepsy.

1986 • 166 citations

gamma-Aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study

1985 • 164 citations

Different neuronal localization of aspartate-like and glutamate-like immunoreactivities in the hippocampus of rat, guinea-pig and senegalese baboon (Papio papio), with a note on the distribution of γ-aminobutyrate

1985 • 162 citations

Monoclonal antibodies demonstrating GABA-like immunoreactivity

1986 • 147 citations

Kindling, Unit Discharge Patterns and Neural Plasticity

1975 • 134 citations

Increased sensitivity in peroxidase immunocytochemistry

1986 • 130 citations

Changes in extracellular Ca²⁺ and K⁺ activity accompanying hippocampal discharges

1980 • 125 citations

Alterations of GABA-mediated synaptic transmission in human epilepsy.

1986 • 119 citations

Potassium and calcium concentrations in interstitial fluid of hippocampal formation during paroxysmal responses

1985 • 118 citations

Calcium and epileptogenesis

1986 • 114 citations

Gamma-aminobutyric acid-immunoreactivity in the rat hippocampus. A light and electron microscopic study with anti-GABA antibodies

1986 • 114 citations

Evidence for impaired GABAergic activity in the substantia nigra of amygdaloid kindled rats

1985 • 109 citations

Seizures produced by pilocarpine: Neuropathological sequelae and activity of glutamate decarboxylase in the rat forebrain

1986 • 98 citations

Further evidence for abnormal GABAergic circuits in amygdala-kindled rats

1987 • 97 citations

Hippocampal slices of kindled rats reveal calcium involvement in epileptogenesis

1985 • 89 citations

The Use of Inhibitors of GABA‐Transaminase for the Determination of GABA Turnover in Mouse Brain Regions: An Evaluation of Aminooxyacetic Acid and Gabaculine

1982 • 85 citations

Changes in local evoked potentials in the rat hippocampus (CA1) during kindling epileptogenesis

1988 • 82 citations

Effect of aminooxyacetic acid, thiosemicarbazide and haloperidol on the metabolism and half-lives of glutamate and GABA in rat brain

1973 • 82 citations

A decrease in the number of GABAergic somata is associated with the preferential loss of GABAergic terminals at epileptic foci

1986 • 77 citations

Orthodromic activation of hippocampal CA1 region of the rat

1979 • 75 citations

Evidence for Feedback Regulation of Glutamate Decarboxylase by γ‐Aminobutyric Acid

1984 • 72 citations

Time course of the reduction of GABA terminals in a model of focal epilepsy: a glutamic acid decar☐ylase immunocytochemical study

1986 • 65 citations

Potentials evoked by alvear tract in hippocampal CA1 region of rats. II. Spatial field analysis

1979 • 62 citations

Decrease in number of hippocampal gamma-aminobutyric acid (GABA) immunoreactive cells in the rat kindling model of epilepsy

1986 • 60 citations

Benzodiazepine/barbiturate/GABA receptor-chloride ionophore complex in a genetic model for generalized epilepsy.

1986 • 56 citations

GLUTAMATE DECARBOXYLASE ACTIVITY IN STRIATAL SLICES: CHARACTERIZATION OF THE INCREASE FOLLOWING DEPOLARIZATION^{1, 2}

1979 • 50 citations

The development of changes in hippocampal GABA immunoreactivity in the rat kindling model of epilepsy: A light microscopic study with gaba antibodies

1987 • 46 citations

Changes in cortical amino acids during electrical kindling in rats

1985 • 42 citations

Cerebral free amino acids in the amygdaloid kindling model of epilepsy

1982 • 37 citations

gamma-Aminobutyric acid concentration, L-glutamate 1-decarboxylase activity, and properties of the gamma-aminobutyric and postsynaptic receptor in cobalt epilepsy in the rat

1981 • 36 citations

Inhibition of the rate of GABA synthesis in regions of rat brain following a convulsion

1987 • 36 citations

Immunocytochemical localization of γ-aminobutyric acid in the rat hippocampal formation

1986 • 36 citations

Inhibition of kindling-induced generalized seizures by aminooxyacetic acid

1980 • 31 citations

Benzodiazepine Receptor Binding Following Amygdala‐Kindled Convulsions: Differing Results in Washed and Unwashed Brain Membranes

1984 • 31 citations

Regulation of γ-aminobutyric acid synthesis in the vertebrate nervous system

1986 • 28 citations

Absence of modifications in γ-aminobutyric acid metabolism after repeated generalized seizures in amygdala-kindled rats

1985 • 22 citations

Inhibitory processes of hippocampal CA1 pyramidal neurons following kindling-induced epilepsy in the rat

1985 • 21 citations

Kindling in the rat hippocampus: Absence of dendritic alterations

1979 • 20 citations

Lack of activated astrocytes in the kindling phenomenon

1978 • 20 citations

Decreased GAB A, Benzodiazepine, and Picrotoxinin Receptor Binding in Brains of Rats After Cobalt‐Induced Epilepsy

1987 • 19 citations

Retardation of resynthesis of GABA-transaminase in some brain regions of amygdala-kindled rats

1986 • 18 citations

Pharmacological and neurochemical aspects of kindling

1985 • 15 citations