Increased sensitivity in peroxidase immunocytochemistry

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

1966 • 6,585 citations

THE UNLABELED ANTIBODY ENZYME METHOD OF IMMUNOHISTOCHEMISTRY PREPARATION AND PROPERTIES OF SOLUBLE ANTIGEN-ANTIBODY COMPLEX (HORSERADISH PEROXIDASE-ANTIHORSERADISH PEROXIDASE) AND ITS USE IN IDENTIFICATION OF SPIROCHETES

1970 • 5,141 citations

Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents.

1978 • 4,337 citations

Technical considerations on the use of horseradish peroxidase as a neuronal marker

1977 • 921 citations

NONDROPLET ULTRASTRUCTURAL DEMONSTRATION OF CYTOCHROME OXIDASE ACTIVITY WITH A POLYMERIZING OSMIOPHILIC REAGENT, DIAMINOBENZIDINE (DAB)

1968 • 892 citations

The afferent connections of the main and the accessory olfactory bulb formations in the rat: An experimental HRP‐study

1978 • 710 citations

Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry.

1982 • 659 citations

SIMULTANEOUS LOCALIZATION OF MULTIPLE TISSUE ANTIGENS USING THE PEROXIDASE-LABELED ANTIBODY METHOD: A STUDY ON PITUITARY GLANDS OF THE RAT

1968 • 651 citations

CYTOCHEMICAL DEMONSTRATION OF PEROXIDASE ACTIVITY WITH 3-AMINO-9-ETHYLCARBAZOLE

1965 • 552 citations

Permeability of muscle capillaries to small heme-peptides. Evidence for the existence of patent transendothelial channels.

1975 • 540 citations

Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalamic magnocellular neurosecretory system of the rat

1975 • 493 citations

Immunocytochemical localization of corticotropin‐releasing factor (CRF) in the rat brain

1982 • 405 citations

Stabilization of the tetramethylbenzidine (TMB) reaction product: application for retrograde and anterograde tracing, and combination with immunohistochemistry.

1984 • 371 citations

Additional factors influencing sensitivity in the tetramethyl benzidine method for horseradish peroxidase neurohistochemistry.

1980 • 351 citations

Sensitivity in horseradish peroxidase neurohistochemistry: a comparative and quantitative study of nine methods.

1979 • 299 citations

A new and sensitive staining method for axonally transported horseradish peroxidase (HRP) in the pigeon visual system

1977 • 278 citations

Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons

1984 • 277 citations

A sensitive low artifact TMB procedure for the demonstration of WGA-HRP in the CNS

1984 • 275 citations

High-grade intensification of the end-product of the diaminobenzidine reaction for peroxidase histochemistry.

1982 • 226 citations

Gonadotropin-releasing hormone (GnRH) neurons and pathways in the rat brain

1984 • 219 citations

A novel immunocytochemical model system for specificity and sensitivity screening of antisera against multiple antigens.

1981 • 218 citations

Application of the silver-gold intensified 3,3′ -diaminobenzidine chromogen to the light and electron microscopic detection of the luteinizing hormone-releasing hormone system of the rat brain

1984 • 206 citations

A sensitive method for histochemical demonstration of horseradish peroxidase in neurons following retrograde axonal transport

1978 • 189 citations

Light and electron microscopic observations on the anterograde transport of horseradish peroxidase in the optic pathway in the mouse and rat

1976 • 180 citations

Visualization of peptide-immunoreactive processes on serotonin-immunoreactive cells using two-color immunoperoxidase staining.

1984 • 166 citations

Stabilizing and rapid thionin staining of TMB-based HRP reaction product

1980 • 139 citations

A safer and more sensitive substitute for diamino-benzidine in the light microscopic demonstration of retrograde and anterograde axonal transport of HRP

1977 • 137 citations

Cortical relay neurons and interneurons in the N. ventralis posterolateralis of cats: A horseradish peroxidase, electron-microscopic, golgi and immunocytochemical study

1983 • 128 citations

Improved immunoglobulin-enzyme bridge method for light microscopic demonstration of hormone-containing cells of the rat adenohypophysis

1975 • 124 citations

Criteria of reliability for light microscopic immunocytochemical staining

1980 • 120 citations

A serotonin-immunoreactive fiber system in the dorsal columns of the spinal cord

1982 • 110 citations

The section-Golgi impregnation procedure. 1. Description of the method and its combination with histochemistry after intracellular iontophoresis or retrograde transport of horseradish peroxidase

1983 • 107 citations

Application of immunoperoxidase techniques to localize horseradish peroxidase-tracer in the central nervous system.

1975 • 107 citations

A MORE SENSITIVE AND SPECIFIC HISTOCHEMICAL PEROXIDASE STAIN FOR THE LOCALIZATION OF CELLULAR ANTIGEN BY THE ENZYME-ANTIBODY CONJUGATE METHOD

1974 • 102 citations

A principle for silver staining of tissue elements by physical development.

1971 • 102 citations

APPLICATION OF PEROXIDASE-LABELLED ANTIBODIES TO THE INTRACELLULAR LOCALIZATION OF HORMONES

1971 • 102 citations

Osmiophilic Polymer Generation: Catalysis by Transition Metal Compounds in Ultrastructural Cytochemistry

1972 • 87 citations

Light Insensitive Physical Developers

1979 • 82 citations

Electron microscopic demonstration of neural connections using horseradish peroxidase: a comparison of the tetramethylbenzidine procedure with seven other histochemical methods.

1982 • 82 citations

Corticotropin Releasing Factor (CRF): Origin and Course of Afferent Pathways to the Median Eminence (ME) of the Rat Hypothalamus

1984 • 78 citations

A comparison of eight different chromogen protocols for the demonstration of immunoreactive neurofilaments or glial filaments in rat cerebellum using the peroxidase-antiperoxidase method and monoclonal antibodies.

1983 • 77 citations

Comparison of horseradish peroxidase visualization methods: quantitative results and further technical specifics.

1981 • 77 citations

Standardization of various applications of methacrylate embedding and silver methenamine for light and electron microscopy immunocytochemistry

1984 • 71 citations

Retrograde horseradish peroxidase tracing combined with localization of choline acetyltransferase immunoreactivity.

1984 • 71 citations

Peroxidase procedures. Technical problems encountered during their application.

1979 • 68 citations

Visualization of the HRP reaction product using the polarization microscope

1979 • 66 citations

Prolactin and growth hormone cells in the human hypophysis: A study with immunoenzyme histochemistry and differential staining

1975 • 66 citations

Self-sandwich Method. An Improved Immunoperoxidase Technic for the Detection of Small Amounts of Antigens

1980 • 64 citations

Localization of biotinylated gonadotropin releasing hormone on pituitary monolayer cells with avidin-biotin-peroxidase complexes.

1983 • 57 citations

Stepwise amplified immunoperoxidase (PAP) staining. I. Cellular morphology in relation to membrane markers.

1984 • 55 citations

Increased sensitivity in immunocytochemistry

1985 • 54 citations

Improvement of the electron microscopic detection of peroxidase activity by means of the silver intensification of the diaminobenzidine reaction in the rat nervous system

1982 • 45 citations

Immunocytochemical demonstration of anterior pituitary hormones in the pars tuberalis of long‐term hypophysectomized rats

1980 • 45 citations

Characterization of a potent biotin-conjugated CRF analog and the response of anterior pituitary corticotropes

1984 • 43 citations

Serotonin-containing projections to the thalamus in the rat revealed by a horseradish peroxidase and peroxidase antiperoxidase double-staining technique

1984 • 43 citations

Facilitated light microscopic cytochemical diagnosis of acute myelogenous leukemia.

1979 • 42 citations

Suppression of the argyrophil III reaction by mercapto compounds (A prerequisite for the intensification of certain histochemical reactions by phasical developers)

1982 • 40 citations

Metal compound intensification of the electron-density of diaminobenzidine.

1983 • 39 citations

Enhancement of immunoperoxidase staining using osmium tetroxide

1983 • 39 citations

A Comparison of Methods Using Diaminobenzidine (Dab) to Localize Peroxidases in Erythrocytes, Neutrophils, and Peroxidase-Antiperoxidase Complex

1978 • 38 citations

A new method for the cytochemical demonstration of peroxidase for light, fluorescence and electron microscopy.

1976 • 38 citations

The luteinizing hormone releasing hormone-containing pathways and their co-termination with tanycyte processes in and around the median eminence and in the pituitary stalk of the rat.

1981 • 35 citations

THE VISUALISATION OF TRACE AMOUNTS OF DIAMINOBENZIDINE (DAB) POLYMER BY A NOVEL GOLD‐SULPHIDE‐SILVER METHOD

1983 • 33 citations

Chemical nature of the first products (nuclei) of the argyrophil staining

1980 • 32 citations

Application of Dual Pre-Embedding Stains for Gonadotropins to Pituitary Cell Monolayers with Avidin-Biotin (ABC) and Peroxidase-Antiperoxidase (PAP) Complexes: Light Microscopic Studies

1983 • 31 citations

Contrast enhancement of the brownish horseradish peroxidase-activated 3,3'-diaminobenzidine tetrahydrochloride reaction product in black and white photomicrography by the use of interference filters.

1984 • 30 citations

Ultrastructural analysis of central serotoninergic neurons immunolabeled by silver-gold-intensified diaminobenzidine chromogen. Completion of immunocytochemistry with X-ray microanalysis.

1985 • 24 citations

Comparison of alternative chromogens for renal immunohistochemistry

1981 • 20 citations

Sensitivity and efficiency of four immunohistochemical methods as defined by staining of artificial sections

1984 • 19 citations

Unusual structure of human splenic sinusoids revealed by monoclonal antibodies

1984 • 19 citations

Simultaneous localization of two different tissue antigens based on the silver intensified PAP-DAB and on the traditional PAP-DAB method.

1983 • 19 citations

Transition metal-catalysed oxidation of 3,3′-diaminobenzidine [DAB] in a model system

1982 • 16 citations

Factors affecting the sensitivity and specificity of the cytochemical reaction for the anti-horseradish peroxidase antibody in lymph tissue sections.

1980 • 15 citations

Immunoperoxidase methods: Increased efficiency using fluorescence microscopy for 3,3-diaminobenzidine (DAB) stained semithin sections

1980 • 15 citations

A quantitative immunoperoxidase procedure employing energy dispersive x-ray analysis.

1979 • 12 citations

230. Silver Intensification of the Diaminobenzidine Reaction Product for Peroxidase Immunocytochemistry.

1982 • 10 citations

The comparative effectiveness of the ‘brown and blue reactions’ for tracing neuronal processes of cells injected intracellularly with horseradish peroxidase

1979 • 10 citations

Potassium ferricyanide: a stabilizer for horseradish peroxidase.

1984 • 6 citations

Histochemical localization of horseradish peroxidase in neurones

1978 • 5 citations

Distribution of peripherally stained neurons by the Colloidal Iron histochemical method in albino rat cerebral cortex. A quantitative study

1980 • 2 citations

Comparison Between Two Chromogenic Substrates for Revealing an Immunoperoxidase Reaction of Human Metaphase Chromosomes

1980 • 2 citations

229. ANTIGEN LOCALIZATION VIA BACKSCATTERED ELECTRON IMAGING USING DIAMINOBENZIDINE COMPLEXED WITH METALS OTHER THAN OSMIUM.

1982 • 1 citations

Deleted Work

1955 • 0 citations

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