11β-Hydroxysteroid dehydrogenase and tissue specificity of androgen action in human prostate cancer cell LNCaP

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

LNCaP model of human prostatic carcinoma.

1983 • 1,749 citations

Mineralocorticoid Action: Target Tissue Specificity Is Enzyme, Not Receptor, Mediated

1988 • 1,607 citations

LOCALISATION OF 11β-HYDROXYSTEROID DEHYDROGENASE—TISSUE SPECIFIC PROTECTOR OF THE MINERALOCORTICOID RECEPTOR

1988 • 1,047 citations

A mutation in the ligand binding domain of the androgen receptor of human INCaP cells affects steroid binding characteristics and response to anti-androgens

1990 • 948 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Purification of a Human Prostate Specific Antigen

2016 • 844 citations

MINERALOCORTICOID ACTIVITY OF LIQUORICE: 11-BETA-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY COMES OF AGE

1987 • 784 citations

PURIFICATION OF HUMAN PROSTATE SPECIFIC ANTIGEN

1979 • 547 citations

A Syndrome of Apparent Mineralocorticoid Excess Associated with Defects in the Peripheral Metabolism of Cortisol*

1979 • 490 citations

Cloning and Expression of Rat cDNA Encoding Corticosteroid 11β-Dehydrogenase

1989 • 452 citations

Prostate antigen: A new potential marker for prostatic cancer

1981 • 341 citations

Purification and Characterization of the Corticosteroid 1lβ-Dehydrogenase Component of the Rat Liver 1lβ-Hydroxysteroid Dehydrogenase Complex*

1988 • 308 citations

Aberrant response in vitro of hormone‐responsive prostate cancer cells to antiandrogens

1989 • 208 citations

Corticosteroid 11β-Dehydrogenase in Rat Testis*

1989 • 181 citations

Hormonal regulation of prostate‐specific antigen (PSA) glycoprotein in the human prostatic adenocarcinoma cell line, LNCaP

1992 • 179 citations

Ontogeny of cortisol-cortisone interconversion in human tissues: A role for cortisone in human fetal development

1981 • 178 citations

Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: High affinity for progestagenic and estrogenic steroids

1990 • 165 citations

Androgen‐dependent growth regulation of and release of specific protein(s) by the androgen receptor containing human prostate tumor cell line LNCaP

1986 • 137 citations

11β-Hydroxysteroid dehydrogenase: Fact or fancy?

1984 • 129 citations

The Intrarenal Localization of Mineralocorticoid Receptors and 11β-Dehydrogenase: Immunocytochemical Studies

1989 • 105 citations

11β-hydroxysteroid dehydrogenase activity (E.C. 1.1.1.146) in human placenta and decidua

1980 • 97 citations

Mechanism of the glucocorticoid regulation of growth of the androgen-sensitive prostate-derived R3327H-G8-A1 tumor cell line.

1985 • 77 citations

Glucocorticoid metabolism in human placenta, decidua, myometrium and fetal membranes

1982 • 70 citations

Tissue-specific expression of an 11 beta-hydroxysteroid dehydrogenase with a truncated N-terminal domain. A potential mechanism for differential intracellular localization within mineralocorticoid target cells.

1992 • 54 citations

Differential effects of androgens and glucocorticoids on regulation of androgen receptor concentrations and cell growth

1984 • 49 citations

Aldosterone-Binding Sites in Pregnant and Lactating Rat Mammary Glands^*

1983 • 43 citations

Specific Region in Hormone Binding Domain Is Essential for Hormone Binding and Trans-Activation by Human Androgen Receptor

1990 • 40 citations

Human glucocorticoid receptor gene promotor—homologous down regulation

1991 • 37 citations

Effect of Hormone Treatment on Prostatic Acid Phosphatase in a Serially Transplantable Human Prostatic Adenocarcinoma (PC-82)

1983 • 35 citations

Proliferation of a highly androgen-sensitive ductus deferens cell line (DDT1MF-2) is regulated by glucocorticoids and modulated by growth on collagen

1983 • 29 citations

Purification of guanylate cyclase from rat liver supernatant.

1978 • 29 citations

Androgen stimulated elevation in androgen receptor levels is inhibited by the synthetic glucocorticoid triamcinolone acetonide

1983 • 26 citations

11β-Hydroxysteroid dehydrogenase and the meaning of life

1990 • 21 citations

NADPH Generating Enzymes in Leydig Cells from Diabetic Rats

1979 • 20 citations

Epithelial and adipose cells isolated from mammary glands of pregnant and lactating rats differ in 11β-hydroxysteroid dehydrogenase activity

1990 • 19 citations

Mechanisms of biphasic action of glucocorticoids on α-lactalbumin production by rat mammary gland explants

1986 • 16 citations

The expression of mRNA for glucocorticoid receptor gene and functional glucocorticoid receptors detected in PA-III rat prostate adenocarcinoma cells.

1992 • 16 citations

Effect of cofactors and luteinizing hormone on testosterone production by rat testis preparations

1976 • 7 citations

Effect of a NADPH generating system on the steroidogenic response in rat luteal cells

1992 • 2 citations