The Influence of Tissue Heterogeneity on Results of Fitting Nonlinear Model Equations to Regional Tracer Uptake Curves: With an Application to Compartmental Models Used in Positron Emission Tomography

THE [¹⁴C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT¹

1977 • 5,986 citations

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

1983 • 3,439 citations

Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method

1979 • 2,396 citations

Brain blood flow measured with intravenous H2(15)O. II. Implementation and validation.

1983 • 1,027 citations

Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain

1984 • 701 citations

Quantitation in Positron Emission Computed Tomography: 5. Physical–Anatomical Effects

1981 • 337 citations

Stochastic flow in capillary blood vessels

1973 • 272 citations

Quantitation in Positron Emission Computed Tomography

1979 • 256 citations

Validation of tomographic measurement of cerebral blood volume with C-11-labeled carboxyhemoglobin.

1979 • 253 citations

Local cerebral glucose utilization in the normal conscious macaque monkey

1978 • 246 citations

Regional Kinetic Constants and Cerebral Metabolic Rate for Glucose in Normal Human Volunteers Determined by Dynamic Positron Emission Tomography of [¹⁸F]-2-Fluoro-2-Deoxy-D-Glucose

1984 • 214 citations

Quantitative Measurement of Local Cerebral Blood Flow in Humans by Positron Computed Tomography and ¹⁵O-Water

1983 • 194 citations

Strategy for the Measurement of Regional Cerebral Blood Flow Using Short-Lived Tracers and Emission Tomography

1984 • 177 citations

A Concurrent Flow Model for Extraction during Transcapillary Passage

1974 • 167 citations

Effect of Ischemia on Quantification of Local Cerebral Glucose Metabolic Rate in Man

1981 • 147 citations

Use of 2-Deoxy-D[1-¹¹C]Glucose for the Determination of Local Cerebral Glucose Metabolism in Humans: Variation within and between Subjects

1982 • 138 citations

Dynamic Positron Emission Tomography for Study of Cerebral Hemodynamics in a Cross Section of the Head Using Positron-Emitting 68Ga-EDTA and 77Kr

1977 • 121 citations

Weighted Integration Method for Local Cerebral Blood Flow Measurements with Positron Emission Tomography

1986 • 116 citations

Computer Assisted Mapping in Quantitative Analysis of Cerebral Positron Emission Tomograms

1985 • 83 citations

Effect of Tissue Heterogeneity on the Measurement of Cerebral Blood Flow with the Equilibrium C¹⁵O₂Inhalation Technique

1983 • 80 citations

An Evaluation of Errors in the Determination of Blood Flow by the Indicator Fractionation and Tissue Equilibration (Kety) Methods

1984 • 78 citations

A Kinetic Evaluation of Blood—Brain Barrier Permeability in Human Brain Tumors with [⁶⁸Ga]EDTA and Positron Computed Tomography

1984 • 78 citations

Cerebral blood flow using PET measurements of fluoromethane kinetics.

1981 • 76 citations

Measurement of Cerebral Blood Flow Using Bolus Inhalation of C¹⁵O₂ and Positron Emission Tomography: Description of the Method and its Comparison with the C¹⁵O₂ Continuous Inhalation Method

1984 • 76 citations

Criteria for the tracer kinetic measurement of cerebral protein synthesis in humans with positron emission tomography

1984 • 65 citations

Local Brain Protein Metabolism in Dementia and Schizophrenia: In Vivo Studies with 11C-L-Methionine and Positron Emission Tomography

1983 • 54 citations

CAPILLARY PERMEABILITY OF HETEROGENEOUS ORGANS: A PARSIMONIOUS INTERPRETATION OF INDICATOR DIFFUSION DATA

1982 • 36 citations