Analysis of spontaneous mutations in a chromosomally located hsv-1 thymidine kinase (TK) gene in a human cell line

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

1964 • 2,108 citations

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

1977 • 1,565 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

Advanced Bacterial Genetics: A Manual for Genetic Engineering

1980 • 856 citations

Mobile genetic elements

1997 • 630 citations

ON THE TOPOGRAPHY OF THE GENETIC FINE STRUCTURE

1961 • 576 citations

Genetic studies of the lac repressor

1978 • 517 citations

On the nature of hereditable variation in cultured somatic cells

1976 • 497 citations

R. W. Davis, D. Botstein and J. R. Roth, A Manual for Genetic Engineering, Advanced Bacterial Genetics. 251 S., 15 Abb. Cold Spring Harbor 1980. Cold Spring Harbor Laboratory. $ 28.20

1981 • 434 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

Handbook of cell and organ culture

1964 • 353 citations

A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2

1982 • 245 citations

Polar mutations in lac, gal and phage λ consist of a few IS-DNA sequences inserted with either orientation

1972 • 210 citations

Non‐producer human cells induced by murine sarcoma virus

1975 • 204 citations

A table for the estimation of the spontaneous mutations rate of cells in culture

1973 • 149 citations

Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells

1983 • 94 citations

High-frequency nonrandom mutational event at the adenine phosphoribosyltransferase (aprt) locus of sib-selected CHO variants heterozygous foraprt

1982 • 87 citations

Syntheses of 5-Trifluoromethyluracil and 5-Trifluoromethyl-2″-Deoxyuridine

1962 • 75 citations

Expression of transferred thymidine kinase genes is controlled by methylation.

1982 • 71 citations

MUTAGENIC MECHANISMS

1969 • 69 citations

Chinese hamster cells deficient in ornithine decarboxylase activity: Reversion by gene amplification and by azacytidine treatment

1985 • 61 citations

High-frequency mutation at the adenine phosphoribosyltransferase locus in Chinese hamster ovary cells due to deletion of the gene.

1983 • 52 citations

Phenotypic Switching in Cells Transformed with the Herpes Simplex Virus Thymidine Kinase Gene

1982 • 52 citations

Coordinate modulation of transfected HSV thymidine kinase and human globin genes

1983 • 41 citations

Comparison of the mutagenic activity of 5-hydroxymethyldeoxyuridine with 5-substituted 2′-deoxyuridine analogs in the Ames Salmonella/microsome test

1986 • 33 citations

High frequency ?switching? at the adenine phosphoribosyltransferase locus in multipotent mouse teratocarcinoma stem cells

1984 • 32 citations

Genetic instability at the adenine phosphoribosyltransferase locus in mouse L cells.

1982 • 27 citations

Phenotypic Variation Associated with Molecular Alterations at a Cluster of Thymidine Kinase Genes

1983 • 18 citations

Changes in Structure and Methylation Pattern in a Cluster of Thymidine Kinase Genes

1984 • 17 citations

Phenotypic variation associated with molecular alterations at a cluster of thymidine kinase genes.

1983 • 13 citations

Changes in structure and methylation pattern in a cluster of thymidine kinase genes.

1984 • 9 citations

A cytotoxic effect associated with 9-(1,3-dihydroxy-2-propoxymethyl)-guanine is observed during the selection for drug resistant human cells containing a single herpesvirus thymidine kinase gene

1985 • 6 citations