Reprograming T cells: the role of extracellular matrix in coordination of T cell activation and migration

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

COLLAGENS: Molecular Biology, Diseases, and Potentials for Therapy

1995 • 1,599 citations

VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

1990 • 1,592 citations

The Discoidin Domain Receptor Tyrosine Kinases Are Activated by Collagen

1997 • 956 citations

A Novel Adaptor Protein Orchestrates Receptor Patterning and Cytoskeletal Polarity in T-Cell Contacts

1998 • 708 citations

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling

2000 • 657 citations

The Collagen-binding A-domains of Integrins α1β1 and α2β1Recognize the Same Specific Amino Acid Sequence, GFOGER, in Native (Triple-helical) Collagens

2000 • 636 citations

Lymph-Borne Chemokines and Other Low Molecular Weight Molecules Reach High Endothelial Venules via Specialized Conduits While a Functional Barrier Limits Access to the Lymphocyte Microenvironments in Lymph Node Cortex

2000 • 562 citations

In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

1997 • 560 citations

An Orphan Receptor Tyrosine Kinase Family Whose Members Serve as Nonintegrin Collagen Receptors

1997 • 510 citations

Cell adhesion: old and new questions

1999 • 426 citations

Antigen Presentation in Extracellular Matrix

2000 • 409 citations

Lymphocyte interactions with extracellular matrix

1991 • 336 citations

Distinct cellular functions mediated by different VLA integrin α subunit cytoplasmic domains

1992 • 307 citations

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

2000 • 295 citations

The collagen receptor integrins have distinct ligand recognition and signaling functions

2000 • 291 citations

Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

1998 • 275 citations

T lymphocytes in human atherosclerotic plaques are memory cells expressing CD45RO and the integrin VLA-1.

1992 • 257 citations

Complexity and specificity of integrin signalling

2000 • 244 citations

Signaling Takes Shape in the Immune System

2000 • 237 citations

Multiple Binding Sites in Collagen Type I for the Integrins α1β1 and α2β1

2000 • 222 citations

Isolation, Cloning, and Sequence Analysis of the Integrin Subunit α10, a β1-associated Collagen Binding Integrin Expressed on Chondrocytes

1998 • 217 citations

Regulation of inflammation by collagen-binding integrins α1β1 and α2β1 in models of hypersensitivity and arthritis

2000 • 215 citations

CD4+ T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize β1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion

1998 • 213 citations

Orchestrated Information Transfer Underlying Leukocyte Endothelial Interactions

1996 • 190 citations

Cutting Edge: Hierarchy of Chemokine Receptor and TCR Signals Regulating T Cell Migration and Proliferation

2000 • 163 citations

cDNA Cloning and Chromosomal Localization of Human α11 Integrin

1999 • 155 citations

Potent Costimulation of Effector T Lymphocytes by Human Collagen Type I

2000 • 64 citations

Integrins and other adhesion molecules on lymphocytes from synovial fluid and peripheral blood of rheumatoid arthritis patients

1992 • 62 citations

Biology of the scleroderma fibroblast

1998 • 58 citations

Reduced Gut Intraepithelial Lymphocytes in VLA1 Null Mice

2000 • 55 citations

Engagement of the α2β1 integrin inhibits Fas ligand expression and activation-induced cell death in T cells in a focal adhesion kinase-dependent manner

2000 • 55 citations

Identification of collagen and laminin receptor integrins on murine T lymphocytes

1994 • 54 citations

Expression and functions of very late antigen 1 in inflammatory joint diseases

1991 • 33 citations

Invasion of collagen gels by mouse lymphoid cells.

1984 • 32 citations