Abnormalities of retinoblastoma gene structure in human lung tumors

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Human Retinoblastoma Susceptibility Gene: Cloning, Identification, and Sequence

1987 • 1,436 citations

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

1989 • 1,186 citations

Abnormalities in Structure and Expression of the Human Retinoblastoma Gene in SCLC

1988 • 905 citations

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.

1991 • 857 citations

Structural Evidence for the Authenticity of the Human Retinoblastoma Gene

1987 • 809 citations

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

1987 • 649 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Malignant transformation of early passage rodent cells by a single mutated human oncogene

1984 • 479 citations

Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein.

1987 • 432 citations

Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma

1988 • 423 citations

The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations.

1990 • 327 citations

Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung.

1988 • 247 citations

Altered Expression of the Retinoblastoma Gene Product in Human Sarcomas

1990 • 221 citations

Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma.

1988 • 204 citations

Structure of the human retinoblastoma gene.

1989 • 193 citations

Inactivation of the retinoblastoma gene in human bladder and renal cell carcinomas.

1991 • 184 citations

Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene.

1990 • 175 citations

Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas

1992 • 167 citations

The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells.

1991 • 163 citations

Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction.

1991 • 162 citations

Non-ocular cancer in relatives of retinoblastoma patients

1989 • 135 citations

Frequent loss of heterozygosity at the retinoblastoma locus in human esophageal cancers.

1991 • 123 citations

Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells.

1985 • 117 citations

Studies of the retinoblastoma gene in human sarcomas.

1989 • 100 citations

Human Retinoblastoma Gene: Long-Range Mapping and Analysis of Its Deletion in a Breast Cancer Cell Line

1989 • 46 citations

Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line.

1989 • 41 citations

Detection of theXbal RFLP within the retinoblastoma locus by PCR

1990 • 39 citations

Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: Organization of the sequence and its encoded protein

1988 • 39 citations

A Psychiatrist's Duty of Confidentiality

1988 • 26 citations

Human lung and bladder carcinoma tumors as compared to their adjacent normal tissue have elevated AP-1 activity associated with the retinoblastoma gene promoter.

1993 • 14 citations