Human Retinoblastoma Gene: Long-Range Mapping and Analysis of Its Deletion in a Breast Cancer Cell Line

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

1987 • 2,353 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Human Retinoblastoma Susceptibility Gene: Cloning, Identification, and Sequence

1987 • 1,436 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

Abnormalities in Structure and Expression of the Human Retinoblastoma Gene in SCLC

1988 • 905 citations

Suppression of the Neoplastic Phenotype by Replacement of the RB Gene in Human Cancer Cells

1988 • 832 citations

Structural Evidence for the Authenticity of the Human Retinoblastoma Gene

1987 • 809 citations

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

1987 • 649 citations

Inactivation of the Retinoblastoma Susceptibility Gene in Human Breast Cancers

1988 • 608 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein.

1987 • 432 citations

Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma

1988 • 423 citations

THE MUTATION AND POLYMORPHISM OF THE HUMAN β-GLOBIN GENE AND ITS SURROUNDING DNA

1984 • 404 citations

Regional Assignment of Genes for Human Esterase D and Retinoblastoma to Chromosome Band 13q14

1980 • 348 citations

Recombination at the human α-globin gene cluster: Sequence features and topological constraints

1987 • 345 citations

The minimum amount of homology required for homologous recombination in mammalian cells.

1984 • 250 citations

Prediction of the Risk of Hereditary Retinoblastoma, Using DNA Polymorphisms within the Retinoblastoma Gene

1988 • 242 citations

Alu-Alu recombination deletes splice acceptor sites and produces secreted low density lipoprotein receptor in a subject with familial hypercholesterolemia.

1987 • 228 citations

Unexpected relationships between four large deletions in the human β-globin gene cluster

1983 • 218 citations

Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma.

1988 • 204 citations

Direct detection of more than 50% of the Duchenne muscular dystrophy mutations by field inversion gels

1987 • 192 citations

Molecular analysis of the Duchenne muscular dystrophy region using pulsed field gel electrophoresis

1987 • 171 citations

Exon-Alu recombination deletes 5 kilobases from the low density lipoprotein receptor gene, producing a null phenotype in familial hypercholesterolemia.

1986 • 168 citations

Independent recombination events between the duplicated human α globin genes; implications for their concerted evolution

1984 • 157 citations

A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster.

1986 • 149 citations

A deletion involving Alu sequences in the beta-hexosaminidase alpha-chain gene of French Canadians with Tay-Sachs disease.

1987 • 148 citations

Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants.

1988 • 126 citations

[35] Strategies for mapping and cloning macroregions of mammalian genomes

1987 • 112 citations

Molecular basis of human growth hormone gene deletions.

1988 • 96 citations

The Minimum Amount of Homology Required for Homologous Recombination in Mammalian Cells

1984 • 94 citations

Molecular cloning of the human esterase D gene, a genetic marker of retinoblastoma.

1986 • 74 citations

Infrequent genomic rearrangement and normal expression of the putative RB1 gene in retinoblastoma tumors.

1988 • 74 citations

Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79.

1988 • 69 citations

Studies on the human retinoblastoma susceptibility gene

1988 • 37 citations

A case of synovial sarcoma with abnormal expression of the human retinoblastoma susceptibility gene

1988 • 35 citations

Oncogene activation by chromosomal rearrangement in chronic myelocytic leukemia

1987 • 24 citations

Molecular detection and differentiation of deletions in band 13q14 in human retinoblastoma.

1986 • 21 citations