Combining Experimental Information from Crystal and Solution Studies: Joint X-Ray and NMR Refinement

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

The nature of the accessible and buried surfaces in proteins

1976 • 1,151 citations

Determination of three‐dimensional structures of proteins from interproton distance data by hybrid distance geometry‐dynamical simulated annealing calculations

1988 • 775 citations

Protein Structure Determination in Solution by Nuclear Magnetic Resonance Spectroscopy

1989 • 444 citations

Structures of Larger Proteins in Solution: Three- and Four-Dimensional Heteronuclear NMR Spectroscopy

1991 • 437 citations

Crystal structure of interleukin 8: symbiosis of NMR and crystallography.

1991 • 354 citations

Refinement of large structures by simultaneous minimization of energy and R factor

1978 • 354 citations

Three-dimensional structure of proteins determined by molecular dynamics with interproton distance restraints: application to crambin.

1986 • 322 citations

Crystal structure of recombinant human interleukin-1β at 2·0 Å resolution

1989 • 177 citations

High-resolution three-dimensional structure of interleukin 1.beta. in solution by three- and four-dimensional nuclear magnetic resonance spectroscopy

1991 • 175 citations

Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.

1989 • 166 citations

Comparison of the high-resolution structures of the α-amylase inhibitor tendamistat determined by nuclear magnetic resonance in solution and by X-ray diffraction in single crystals

1989 • 150 citations

OMITMAP: An electron density map suitable for the examination of errors in a macromolecular model

1984 • 117 citations

Functional implications of interleukin‐1β based on the three‐dimensional structure

1992 • 80 citations

Solution conformations of human growth hormone releasing factor: comparison of the restrained molecular dynamics and distance geometry methods for a system without long-range distance data

1987 • 71 citations

Solution of a Protein Crystal Structure with a Model Obtained from NMR Interproton Distance Restraints

1987 • 64 citations

A procedure for joint refinement of macromolecular structures with X-ray and neutron diffraction data from single crystals

1982 • 63 citations

Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8

1991 • 56 citations

Comparison of the solution nuclear magnetic resonance and X-ray crystal structures of human recombinant interleukin-1β

1991 • 51 citations

Nuclear magnetic resonance solution and X-ray structures of squash trypsin inhibitor exhibit the same conformation of the proteinase binding loop

1989 • 50 citations

Solution of the phase problem in the X-ray diffraction method for proteins with the nuclear magnetic resonance solution structure as initial model

1989 • 39 citations