Ethanolic extracts of black cohosh (Actaea racemosa) inhibit growth and oestradiol synthesis from oestrone sulphate in breast cancer cells

Breast cancer and hormone-replacement therapy in the Million Women Study

2003 • 2,896 citations

Influence of Estrogen Plus Progestin on Breast Cancer and Mammography in Healthy Postmenopausal Women

2003 • 1,839 citations

Breast cancer and hormone-replacement therapy: the Million Women Study

2003 • 1,197 citations

Phyto-oestrogens, their mechanism of action: current evidence for a role in breast and prostate cancer

2004 • 340 citations

The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study: effects on menopause symptoms and bone markers

2003 • 279 citations

Estrogen—the Good, the Bad, and the Unexpected

2005 • 252 citations

Phytoestrogens Induce Differential Estrogen Receptor Alpha- or Beta-Mediated Responses in Transfected Breast Cancer Cells

2005 • 235 citations

Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells.

2001 • 216 citations

Effects of phytoestrogens on aromatase, 3β and 17β-hydroxysteroid dehydrogenase activities and human breast cancer cells

2000 • 212 citations

Comparative study of oestrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells

2005 • 191 citations

The selective estrogen enzyme modulators in breast cancer: a review

2004 • 190 citations

Estrogen-Specific 17 -Hydroxysteroid Oxidoreductase Type 1 (E.C. 1.1.1.62) as a Possible Target for the Action of Phytoestrogens

1995 • 167 citations

Induction and Inhibition of Aromatase (CYP19) Activity by Natural and Synthetic Flavonoid Compounds in H295R Human Adrenocortical Carcinoma Cells

2004 • 158 citations

Effects of phytoestrogens on DNA synthesis in MCF‐7 cells in the presence of estradiol or growth factors

1998 • 146 citations

Endocrine-disrupting chemicals as modulators of sex steroid synthesis

2006 • 143 citations

Menopause: a review of botanical dietary supplements

2005 • 130 citations

Efficacy ofCimicifuga racemosaon climacteric complaints: A randomized study versus low-dose transdermal estradiol

2005 • 129 citations

Growth Inhibitory Activity of Extracts and Purified Components of Black Cohosh on Human Breast Cancer Cells

2004 • 122 citations

Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha

2006 • 120 citations

Botanical and Dietary Supplements for Menopausal Symptoms: What Works, What Does Not

2005 • 116 citations

Phytoestrogens Are Potent Inhibitors of Estrogen Sulfation: Implications for Breast Cancer Risk and Treatment

2004 • 116 citations

Pharmacological effects of Cimicifuga racemosa

2003 • 110 citations

Elevated steroid sulfatase expression in breast cancers

2000 • 107 citations

In vitro effects of the Cimicifuga racemosa extract BNO 1055

2003 • 106 citations

Type 5 17β-hydroxysteroid dehydrogenase: its role in the formation of androgens in women

2001 • 101 citations

High expression of steroid sulfatase mRNA predicts poor prognosis in patients with estrogen receptor-positive breast cancer.

2003 • 100 citations

Dose–response effects of phytoestrogens on the activity and expression of 3β-hydroxysteroid dehydrogenase and aromatase in human granulosa-luteal cells

2005 • 91 citations

Influence of Cimicifuga Racemosa on the Proliferation of Estrogen Receptor-Positive Human Breast Cancer Cells

2002 • 90 citations

Daidzein Sulfoconjugates Are Potent Inhibitors of Sterol Sulfatase (EC 3.1.6.2)

1997 • 88 citations

Differences between human breast cell lines in susceptibility towards growth inhibition by genistein

2001 • 80 citations

Phytoestrogens: A Viable Option?

2002 • 69 citations

Evaluation of Cell Death Caused by Triterpene Glycosides and Phenolic Substances from Cimicifuga racemosa Extract in Human MCF-7 Breast Cancer Cells

2004 • 68 citations

In vitro effects of diethylstilbestrol, genistein, 4-tert-butylphenol, and 4-tert-octylphenol on steroidogenic activity of isolated immature rat ovarian follicles

2004 • 66 citations

Phytoestrogens inhibit aromatase but not 17beta-hydroxysteroid dehydrogenase (HSD) type 1 in human granulosa-luteal cells: evidence for FSH induction of 17beta-HSD

2003 • 65 citations

Black Cohosh (Actaea/Cimicifuga racemosa)

2005 • 64 citations

Activity and gene expression of 17β-hydroxysteroid dehydrogenase type I in primary cultures of epithelial and stromal cells derived from normal and tumourous human breast tissue: the role of IL-8

1998 • 59 citations

The impact of clinical trials on the use of hormone replacement therapy

2005 • 54 citations

Inhibition of estrone sulfatase in human liver microsomes by quercetin and other flavonoids

1997 • 54 citations

Is Black Cohosh Estrogenic?

2003 • 51 citations

Black cohosh: just another phytoestrogen?

2005 • 50 citations

17-Beta-Hydroxysteroid Dehydrogenase in Human Breast and Endometrial Carcinoma

2000 • 46 citations

Effects of Phytoestrogens and Synthetic Combinatorial Libraries on Aromatase, Estrogen Biosynthesis, and Metabolism

2001 • 35 citations

Effect of clinical trial publicity on HRT prescribing in Ireland

2006 • 35 citations

Hot flashes revisited: Pharmacological and herbal options for hot flashes management. What does the evidence tell us?

2005 • 32 citations

Synergistic Effects Induced by Cycloprodigiosin Hydrochloride and Epirubicin on Human Breast Cancer Cells

2002 • 16 citations

Hot flashes revisited: Pharmacological and herbal options for hot flashes management. What does the evidence tell us?

2005 • 11 citations

PHYTOESTROGENS INHIBIT mRNA EXPRESSION AND ACTIVITY OF AROMATASE IN HUMAN GRANULOSA-LUTEAL (GL) CELLS

2004 • 2 citations