DCPIB is a novel selective blocker of I_Cl,swell and prevents swelling‐induced shortening of guinea‐pig atrial action potential duration

Inactivation of the sodium channel. I. Sodium current experiments.

1977 • 1,509 citations

The heart and cardiovascular system

1986 • 1,333 citations

Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction

1989 • 995 citations

Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

1997 • 652 citations

A chloride channel widely expressed in epithelial and non-epithelial cells

1992 • 594 citations

Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea‐pig heart.

1984 • 560 citations

Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide.

1993 • 512 citations

Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In Xenopus Oocytes

1991 • 498 citations

Myocardial ischemia revisited. The osmolar load, membrane damage, and reperfusion

1986 • 313 citations

Cloning and Functional Expression of Rat CLC-5, a Chloride Channel Related to Kidney Disease

1995 • 279 citations

Tissue osmolality, cell swelling, and reperfusion in acute regional myocardial ischemia in the isolated porcine heart.

1981 • 264 citations

Autonomic Regulation of a Chloride Current in Heart

1989 • 254 citations

Mutational Analysis Demonstrates That ClC-4 and ClC-5 Directly Mediate Plasma Membrane Currents

1999 • 242 citations

Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla.

1993 • 235 citations

Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes

1998 • 230 citations

Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen).

1994 • 219 citations

Hypotonicity activates a native chloride current in Xenopus oocytes.

1994 • 216 citations

Stretch‐activated anion currents of rabbit cardiac myocytes.

1992 • 208 citations

Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene.

1991 • 196 citations

Role of external Ca2+ and K+ in gating of cardiac delayed rectifier K+ currents

1992 • 190 citations

Activation of a Cl- current by hypotonic volume increase in human endothelial cells.

1994 • 187 citations

Purification and Reconstitution of Chloride Channels from Kidney and Trachea

1989 • 186 citations

Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method.

1992 • 184 citations

Myocardial oedema: a preventable cause of reperfusion injury?

1993 • 146 citations

Calcium‐activated chloride channels in bovine pulmonary artery endothelial cells.

1997 • 146 citations

Regulation of cellular volume in rabbit ventricular myocytes: bumetanide, chlorothiazide, and ouabain

1991 • 141 citations

Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology.

1994 • 133 citations

Cell swelling and ion transport pathways in cardiac myocytes

1996 • 132 citations

Role of cardiac chloride currents in changes in action potential characteristics and arrhythmias

1998 • 112 citations

Enhancement of the L-Type Ca ²⁺ Current by Mechanical Stimulation in Single Rabbit Cardiac Myocytes

1996 • 100 citations

A chloride current associated with swelling of cultured chick heart cells.

1993 • 97 citations

Contribution of a swelling-activated chloride current to changes in the cardiac action potential

1997 • 74 citations

Characterization of a Human and Murine Gene (CLCN3) Sharing Similarities to Voltage-Gated Chloride Channels and to a Yeast Integral Membrane Protein

1995 • 74 citations

Positive regulation by chloride channel blockers of IsK channels expressed in Xenopus oocytes.

1994 • 71 citations

Effect of osmotic swelling and shrinkage on Na(+)-K+ pump activity in mammalian cardiac myocytes

1993 • 70 citations

Kinetic and pharmacological properties of the calciumm-activated chloride-current in macrovascular endothelial cells

1997 • 69 citations

Cardiac swelling-induced chloride current depolarizes canine atrial myocytes

1997 • 64 citations

Cell swelling has differential effects on the rapid and slow components of delayed rectifier potassium current in guinea pig cardiac myocytes.

1995 • 55 citations

Transmembrane chloride currents in human atrial myocytes

1996 • 54 citations

Pharmacologic Properties of the Swelling‐Induced Chloride Current of Dog Atrial Myocytes

1994 • 52 citations

Length, width, and volume changes in osmotically stressed myocytes

1986 • 45 citations

Chloride conductance in human atrial cells

1995 • 40 citations

Intracellular cyclic AMP inhibits native and recombinant volume‐regulated chloride channels from mammalian heart

2000 • 40 citations

Arrhythmogenic effects of isoproterenol-activated Cl− current in guinea-pig ventricular myocytes

1992 • 37 citations

Adenosine-stimulated astroglial swelling in cat cerebral cortex in vivo with total inhibition by a non-diuretic acylaryloxyacid derivative

1981 • 34 citations

Influence of potassium ions and osmolality on the resting membrane potential of rabbit ventricular papillary muscle with estimation of the activity and the activity coefficient of internal potassium.

1975 • 32 citations

Effects of stilbenedisulfonic acid derivatives on the cAMP-regulated chloride current in cardiac myocytes

1993 • 30 citations

ION Channels and Membrane Receptors in Follicle-Enclosed Xenopus Oocytes

1996 • 28 citations

Functional role of follicular cells in the generation of osmolarity‐dependent Cl‐ currents in Xenopus follicles.

1995 • 24 citations

Cell swelling causes the action potential duration to shorten in guinea-pig ventricular myocytes by activating I KATP

1998 • 22 citations

Cardiac chloride channels: physiology, pharmacology and approaches for identifying novel modulators of activity

2000 • 19 citations

Effects of hypertonic solution on action potential and input resistance in the guinea-pig ventricular muscle.

1983 • 14 citations

EFFECTS OF OSMOLARITY CHANGE ON THE EXCITATION-CONTRACTION COUPLING OF BULLFROG VENTRICLE

1974 • 13 citations