Enhancement of the L-Type Ca ²⁺ Current by Mechanical Stimulation in Single Rabbit Cardiac Myocytes

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Calcium Channel

1981 • 1,184 citations

Calcium tolerant ventricular myocytes prepared by preincubation in a ?KB medium?

1982 • 917 citations

Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino‐atrial node cells.

1988 • 780 citations

The variance of sodium current fluctuations at the node of Ranvier

1980 • 772 citations

A novel type of cardiac calcium channel in ventricular cells

1985 • 745 citations

Mechanosensitive ion channels

1990 • 721 citations

Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.

1985 • 715 citations

Cardiac pacemaking in the sinoatrial node

1993 • 665 citations

Inactivation of Ca channels

1984 • 616 citations

Localization of beta adrenergic receptors, and effects of noradrenaline and cyclic nucleotides on action potentials, ionic currents and tension in mammalian cardiac muscle

1974 • 422 citations

On the mechanism of ?-adrenergic regulation of the Ca channel in the guinea-pig heart

1985 • 396 citations

A Mechanosensitive Ion Channel in the Yeast Plasma Membrane

1988 • 382 citations

Cyclic AMP Mediates the Effects of Adrenaline on Cardiac Purkinje Fibres

1972 • 346 citations

Involvement of stretch-activated ion channels in Ca2+ mobilization to mechanical stretch in endothelial cells

1993 • 288 citations

Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes

1989 • 271 citations

Tissue osmolality, cell swelling, and reperfusion in acute regional myocardial ischemia in the isolated porcine heart.

1981 • 264 citations

Modulation of Ca current during the phosphorylation cycle in the guinea pig heart

1986 • 254 citations

?Run-down? of the Ca current during long whole-cell recordings in guinea pig heart cells: role of phosphorylation and intracellular calcium

1988 • 239 citations

Stretch‐activated anion currents of rabbit cardiac myocytes.

1992 • 208 citations

Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method.

1992 • 184 citations

Cell swelling increases membrane conductance of canine cardiac cells: evidence for a volume-sensitive Cl channel

1992 • 181 citations

The protein kinase A-regulated cardiac CI− channel resembles the cystic fibrosis transmembrane conductance regulator

1992 • 170 citations

Properties and regulation of calcium channels in muscle cells

1990 • 168 citations

Background current in sino‐atrial node cells of the rabbit heart.

1992 • 164 citations

Modulation by intracellular ATP and cyclic AMP of the slow inward current in isolated single ventricular cells of the guinea‐pig.

1983 • 164 citations

Stretch-activated ion channels in tissue-cultured chick heart

1993 • 158 citations

Regulation of intracellular fluid volume and disease

1970 • 157 citations

Novel cation-selective mechanosensitive ion channel in the atrial cell membrane.

1993 • 136 citations

Calcium channel currents recorded from isolated myocytes of rat basilar artery are stretch sensitive.

1993 • 130 citations

Phosphorylation-Independent Modulation of L-Type Calcium Channels by Magnesium-Nucleotide Complexes

1992 • 125 citations

Phosphorylation restores activity of L‐type calcium channels after rundown in inside‐out patches from rabbit cardiac cells.

1992 • 123 citations

Effects of Mechanical Stretch on Membrane Currents of Single Ventricular Myocytes of Guinea-Pig Heart.

1992 • 114 citations

Augmentation of cardiac calcium current by flash photolysis of intracellular caged-Ca2+ molecules

1989 • 104 citations

Inhibition of the calcium channel by intracellular protons in single ventricular myocytes of the guinea‐pig.

1988 • 99 citations

Effects of magnesium on inactivation of the voltage-gated calcium current in cardiac myocytes.

1989 • 86 citations

Effect of stretch on the isolated cat sinoatrial node

1966 • 79 citations

Effects of localized stretch of the sinoatrial node region of the dog heart

1966 • 78 citations

Stretching increases calcium influx and efflux in cultured pulmonary arterial smooth muscle cells

1992 • 42 citations

Stretch-induced activation of Ca2+-permeable ion channels is involved in the volume regulation of hypotonically swollen epithelial cells

1990 • 39 citations

Ca(2+)‐dependent block and potentiation of L‐type calcium current in guinea‐pig ventricular myocytes.

1993 • 35 citations

Substrate activation of mechanosensitive, whole cell currents in renal proximal tubule

1993 • 35 citations

Activity of cardiac L-type Ca2+ channels is sensitive to cytoplasmic calcium

1992 • 31 citations