Overexpression of laminin ?1 chain in colonic cancer cells induces an increase in tumor growth

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Laminin–a glycoprotein from basement membranes.

1979 • 2,372 citations

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

Form and function: The laminin family of heterotrimers

2000 • 1,226 citations

The Laminin α Chains: Expression, Developmental Transitions, and Chromosomal Locations of α1-5, Identification of Heterotrimeric Laminins 8–11, and Cloning of a Novel α3 Isoform

1997 • 661 citations

Role of laminin a chain in the development of epithelial cell polarity

1988 • 488 citations

Growth adaptation to methotrexate of HT-29 human colon carcinoma cells is associated with their ability to differentiate into columnar absorptive and mucus-secreting cells.

1990 • 414 citations

Laminin mediates tissue-specific gene expression in mammary epithelia.

1995 • 397 citations

Enterocytic differentiation of a subpopulation of the human colon tumor cell line HT‐29 selected for growth in sugar‐free medium and its inhibition by glucose

1985 • 343 citations

The integrin alpha 6 beta 4 is a laminin receptor.

1992 • 299 citations

Key Role of the Cdx2 Homeobox Gene in Extracellular Matrix–mediated Intestinal Cell Differentiation

1997 • 271 citations

Developmental Regulation of the Laminin α5 Chain Suggests a Role in Epithelial and Endothelial Cell Maturation

1997 • 261 citations

Reconstituted basement membrane (matrigel) and laminin can enhance the tumorigenicity and the drug resistance of small cell lung cancer cell lines.

1990 • 249 citations

Recognition of the laminin E8 cell-binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubules.

1990 • 243 citations

Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by α3β1, α6β1 and α6β4 integrins

2000 • 227 citations

Enhanced Tumor Growth of Both Primary and Established Human and Murine Tumor Cells in Athymic Mice After Coinjection With Matrigel

1991 • 216 citations

Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo

1992 • 198 citations

Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin β4 cytoplasmic domain

1998 • 197 citations

Laminins: Structure and genetic regulation

2000 • 196 citations

Role of the SIKVAV Site of Laminin in Promotion of Angiogenesis and Tumor Growth: An In Vivo Matrigel Model

1992 • 185 citations

Differential expression of laminin-5 subunits and integrin receptors in human colorectal neoplasia

1998 • 169 citations

Laminin α1-Chain Shows a Restricted Distribution in Epithelial Basement Membranes of Fetal and Adult Human Tissues

2000 • 164 citations

Differential expression of five laminin α (1-5) chains in developing and adult mouse kidney

1997 • 152 citations

Inhibition of laminin alpha 1-chain expression leads to alteration of basement membrane assembly and cell differentiation.

1996 • 149 citations

Enhancement of tumorigenicity of human breast adenocarcinoma cells in nude mice by matrigel and fibroblasts

1993 • 146 citations

The α chain of laminin-1 is independently secreted and drives secretion of its β- and γ-chain partners

1997 • 144 citations

Intestinal Epithelial‐Mesenchymal Cell Interactions

1998 • 128 citations

The integrin α6β4 and the biology of carcinoma

1996 • 123 citations

Differential expression of laminin isoforms and α6‐β4 integrin subunits in the developing human and mouse intestine

1994 • 116 citations

Mapping of Network-forming, Heparin-binding, and α1β1 Integrin-recognition Sites within the α-Chain Short Arm of Laminin-1

1995 • 115 citations

Integrins: alternative splicing as a mechanism to regulate ligand binding and integrin signaling events

1999 • 108 citations

Expression of laminin α1, α5 and β2 chains during embryogenesis of the kidney and vasculature

1996 • 104 citations

Tumour basement membrane laminin in adenocarcinoma of rectum: An immunohistochemical study of biological and clinical significance

1986 • 93 citations

Changes in the expression of laminin during intestinal development

1991 • 87 citations

A novel laminin E8 cell adhesion site required for lung alveolar formation in vitro

1994 • 84 citations

Developmental Expression and Cellular Origin of the Laminin α2, α4, and α5 Chains in the Intestine

1999 • 80 citations

Dual and asynchronous deposition of laminin chains at the epithelial-mesenchymal interface in the gut

1992 • 70 citations

Modulation of Angiogenesis in Vitro by Laminin-Entactin Complex

1994 • 69 citations

Laminin and collagen IV subunit distribution in normal and neoplastic tissues of colorectum and breast

1997 • 69 citations

The Role of Basement Membrane in Angiogenesis and Tumor Growth

1994 • 66 citations

Proteolytic modification of laminins: Functional consequences

2000 • 54 citations

Laminin-α1-chain sequence Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastases

1998 • 49 citations

Identification of Metastasis-Promoting Sequences in the Mouse Laminin α1 Chain

1999 • 45 citations

Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies

1992 • 45 citations

Adhesion complexes implicated in intestinal epithelial cell-matrix interactions

2000 • 44 citations

Laminin α1 chain G domain peptide, RKRLQVQLSIRT, inhibits epithelial branching morphogenesis of cultured embryonic mouse submandibular gland

1998 • 44 citations

Effect of reconstituted basement membrane components on the growth of a panel of human tumour cell lines in nude mice

1993 • 40 citations

Polarized Expression of HD1: Relationship with the Cytoskeleton in Cultured Human Colonic Carcinoma Cells

1997 • 37 citations

The laminin alpha 1 chain Ile-Lys-Val-Ala-Val (IKVAV)-containing peptide promotes liver colonization by human colon cancer cells.

1995 • 36 citations

Adhesive properties and integrin expression profiles of two colonic cancer populations differing by their spreading on laminin

1994 • 33 citations

Matrix metalloproteinases in gastrointestinal cancer

1998 • 32 citations

Patterns and composition of basement membranes in colon adenomas and adenocarcinomas

1993 • 28 citations

Reconstituted basement membrane (matrigel) promotes the survival and influences the growth of murine tumors

1992 • 26 citations

Characterization of tumorigenic sub-lines from a poorly tumorigenic human colon-adenocarcinoma cell line

1996 • 22 citations

Human tumor spontaneous metastasis in immunosuppressed newborn rats. I. Characterization of the bioassay

1991 • 21 citations

Changes in glycosaminoglycan synthesis and in heparan sulfate deposition in human colorectal adenocarcinomas

1990 • 16 citations

Immunohistochemical Localization of Laminin, Collagen Type IV and Heparan Sulfate Proteoglycan in Human Colorectal Adenocarcinoma: Correlation with Local Invasive Pattern and Lymph Node Metastasis.

1998 • 14 citations

Expression of the Long Arm Sequence of Mouse Laminin 1, 1, or ;l Chain in COSl Cells and Assembly of Monkey-Mouse Hybrid Laminin

1997 • 7 citations

Deleted Work

1955 • 0 citations