Transcriptional Activation by Wild-Type but Not Transforming Mutants of the p53 Anti-Oncogene

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1984 • 754 citations

Wild-type p53 can inhibit oncogene-mediated focus formation.

1989 • 738 citations

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

1988 • 705 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

Common DNA binding site for Fos protein complexesand transcription factor AP-1

1988 • 613 citations

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1984 • 606 citations

Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation

1989 • 599 citations

Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

1984 • 524 citations

Rearrangement of the p53 gene in human osteogenic sarcomas.

1987 • 489 citations

Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins

1989 • 358 citations

GAL4 activates gene expression in mammalian cells

1988 • 355 citations

Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus

1984 • 341 citations

Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53.

1983 • 313 citations

Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb

1989 • 302 citations

Activating Mutations for Transformation by p53 Produce a Gene Product That Forms an hsc70-p53 Complex with an Altered Half-Life

1988 • 298 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

DNA-bound Fos proteins activate transcription in yeast

1988 • 223 citations

Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex

1986 • 175 citations

Cloning and characterization of a cDNA from Xenopus laevis coding for a protein homologous to human and murine p53.

1987 • 158 citations

Regulation of the cellular p53 tumor antigen in teratocarcinoma cells and their differentiated progeny.

1982 • 111 citations

Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53

1983 • 104 citations

The amino acid sequence of murine p53 determined from a c-DNA clone

1984 • 104 citations

DNA binding properties of murine p53.

1988 • 100 citations

P53 transformation-related protein accumulates in the nucleus of transformed fibroblasts in association with the chromatin and is found in the cytoplasm of non-transformed fibroblasts.

1983 • 93 citations

Regulation of the Cellular p53 Tumor Antigen in Teratocarcinoma Cells and Their Differentiated Progeny

1982 • 35 citations