Increased production of gelatinase B (matrix metalloproteinase‐9) and interleukin‐6 by activated rat microglia in culture

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism.

1992 • 1,121 citations

Interleukin 1 of the central nervous system is produced by ameboid microglia.

1986 • 858 citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

1990 • 459 citations

Brain macrophages: evaluation of microglia and their functions

1992 • 443 citations

Macrophages, lymphocytes, and plasma cells in the perivascular compartment in chronic multiple sclerosis.

1978 • 419 citations

Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells

1988 • 368 citations

Monokine production by microglial cell clones

1989 • 366 citations

Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders

1992 • 286 citations

Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA)

1991 • 278 citations

Cytokines Regulate Gelatinase A and B (Matrix Metalloproteinase 2 and 9) Activity in Cultured Rat Astrocytes

1995 • 193 citations

Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein

1993 • 192 citations

Peripheral nerve lesion produces increased levels of major histocompatibility complex antigens in the central nervous system

1989 • 189 citations

Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells.

1990 • 180 citations

Inflammatory glia mediate delayed neuronal damage after ischemia in the central nervous system.

1993 • 155 citations

Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma.

1990 • 146 citations

Regulation of interleukin-6 (IL-6) secretion in primary cultured rat astrocytes: synergism of interleukin-1 (IL-1) and pituitary adenylate cyclase activating polypeptide (PACAP)

1994 • 132 citations

Interleukin 6 enhances the production of tissue inhibitor of metalloproteinases (TIMP) but not that of matrix metalloproteinases by human fibroblats

1990 • 109 citations

Fibronectin and laminin regulate thein vitro differentiation of microglial cells

1991 • 98 citations

Immunocytochemical identification and quantitation of the mononuclear cells in the cerebrospinal fluid, meninges, and brain during acute viral meningoencephalitis.

1984 • 98 citations

Hypoperfusion and vasoreactivity in the thalamus and cerebellum after stroke.

1993 • 86 citations

Protease production by cultured microglia: Substrate gel analysis and immobilized matrix degradation

1993 • 83 citations

Cytokine-mediated regulation of rat ovarian function: interleukin-1 stimulates the accumulation of a 92-kilodalton gelatinase.

1993 • 81 citations

Invasion of brain tissue by primary glioma: Evidence for the involvement of urokinase-type plasminogen activator as an activator of type iv collagenase

1992 • 58 citations

Cytokine-mediated regulation of rat ovarian function: interleukin-1 stimulates the accumulation of a 92-kilodalton gelatinase

1993 • 26 citations

Characterization of brain microglia and the biological significance in the central nervous system.

1993 • 18 citations

Aseptic meningitis in children: Correlation between fever and interferon-gamma level

1991 • 17 citations