Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk

The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I

1995 • 3,492 citations

The Role of Glutathione and Glutathione Transferases in Chemical Cardnogenesi

1990 • 466 citations

Food-derived mutagens and carcinogens.

1992 • 450 citations

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites

1992 • 417 citations

Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.

1994 • 393 citations

Nutrition and colorectal cancer

1996 • 367 citations

Meat, cooking methods and colorectal cancer: A case‐referent study in Stockholm

1991 • 325 citations

Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite andN-nitroso compounds: a follow-up study

1999 • 315 citations

Heterocyclic amine content in beef cooked by different methods to varying degrees of doneness and gravy made from meat drippings

1998 • 286 citations

High concentrations of the carcinogen 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine (PhIP) occur in chicken but are dependent on the cooking method.

1995 • 269 citations

Cigarette Smoking and Colorectal Cancer Mortality in the Cancer Prevention Study II

2000 • 261 citations

N- and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells

1992 • 248 citations

Well-done, grilled red meat increases the risk of colorectal adenomas.

1999 • 226 citations

Heterocyclic amine content of pork products cooked by different methods and to varying degrees of doneness

1998 • 222 citations

Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression

2001 • 217 citations

A case-control study of occupational and dietary factors in colorectal cancer in young men by subsite.

1989 • 210 citations

Meat consumption, genetic susceptibility, and colon cancer risk: a United States multicenter case-control study.

1999 • 186 citations

Dietary intake of heterocyclic amines, meat-derived mutagenic activity, and risk of colorectal adenomas.

2001 • 186 citations

DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

1999 • 167 citations

Heterocyclic amine content in fast-food meat products

1995 • 152 citations

Metabolic activation of N-hydroxy arylamines and N-hydroxy heterocyclic amines by human sulfotransferase(s).

1995 • 149 citations

Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-l-methyl-6-phenyUmidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues

1994 • 141 citations

Analysis of DNA Adducts of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Rat and Human Tissues by Alkaline Hydrolysis and Gas Chromatography/Electron Capture Mass Spectrometry: Validation by Comparison with 32P-Postlabeling

1994 • 139 citations

Meat Consumption and Colorectal Cancer: A Review of Epidemiologic Evidence

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Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.

1994 • 131 citations

Phenol sulphotransferase SULT1A1 polymorphism: molecular diagnosis and allele frequencies in Caucasian and African populations

1998 • 127 citations

The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk

2001 • 109 citations

Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States).

1997 • 104 citations

Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines

1998 • 100 citations

Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies

1997 • 91 citations

FRIED FOODS AND THE RISK OF COLON CANCER

1988 • 90 citations

Relationship of phenol sulfotransferase activity (SULT1A1) genotype to sulfotransferase phenotype in platelet cytosol

2000 • 89 citations

Isolation and identification of mutagens from a fried Norwegian meat product

1988 • 84 citations

Ultimate forms of mutagenic and carcinogenic heterocyclic amines produced by pyrolysis

1983 • 84 citations

The consumption of well-done red meat and the risk of colorectal cancer.

1994 • 83 citations

A simple colorimetric assay for phenotyping the major human thermostable phenol sulfotransferase (SULT1A1) using platelet cytosols.

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Activation of 2-amino-1-methyl-6-phenyimidazo[4,5-b] pyridine (PhIP) to mutagenic metabolites

1990 • 56 citations

A study of gender-based cytochrome P4501A2 variability: a possible mechanism for the male excess of bladder cancer.

1995 • 56 citations

CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.

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The effects of flavonoids on human phenolsulphotransferases: Potential in drug metabolism and chemoprevention

1999 • 42 citations

Cooked-food mutagen reference list and index

1988 • 35 citations

Phenol sulphotransferase SULT1A1 polymorphism: molecular diagnosis and allele frequencies in Caucasian and African populations

1999 • 30 citations

A comparison of mutagen production in fried ground chicken and beef: effect of supplemental creatine

1988 • 28 citations