Behavioral effects of excitotoxic lesions of ventral medial prefrontal cortex in the rat are hemisphere-dependent

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Subgenual prefrontal cortex abnormalities in mood disorders

1997 • 2,646 citations

The Prefrontal Cortex: Anatomy, Physiology, and Neuropsychology of the Frontal Lobe

1980 • 2,401 citations

Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions

2000 • 1,874 citations

Individuals with sociopathic behavior caused by frontal damage fail to respond autonomically to social stimuli

1990 • 1,275 citations

A review of the validity and variability of the Elevated Plus-Maze as an animal model of anxiety

1996 • 1,160 citations

The prefrontal cortex: Anatomy, physiology, and neuropsychology of the frontal lobe

1989 • 1,147 citations

Central regulation of autonomic functions

1991 • 1,124 citations

The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress

1993 • 1,118 citations

MOOD DISORDERS IN STROKE PATIENTS: IMPORTANCE OF LOCATION OF LESION

1984 • 1,079 citations

Selective activation of the mesocortical DA system by stress

1976 • 1,037 citations

Extinction of emotional learning: Contribution of medial prefrontal cortex

1993 • 895 citations

Efferent projections of the infralimbic cortex of the rat

1991 • 768 citations

Left frontal hypoactivation in depression.

1991 • 752 citations

Left frontal hypoactivation in depression.

1991 • 696 citations

Cerebral asymmetry, emotion, and affective style.

1995 • 667 citations

Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats.

1995 • 656 citations

Stress Preferentially Increases Extraneuronal Levels of Excitatory Amino Acids in the Prefrontal Cortex: Comparison to Hippocampus and Basal Ganglia

1993 • 565 citations

Hemispheric laterality in animals and the effects of early experience

1981 • 547 citations

Involvement of the Prelimbic–Infralimbic Areas of the Rodent Prefrontal Cortex in Behavioral Flexibility for Place and Response Learning

1999 • 546 citations

Conditioned fear-induced changes in behavior and in the expression of the immediate early gene c-fos: with and without diazepam pretreatment

1995 • 536 citations

Left prefrontal glucose hypometabolism in the depressed state: a confirmation

1990 • 468 citations

Lateralized Effects of Medial Prefrontal Cortex Lesions on Neuroendocrine and Autonomic Stress Responses in Rats

1999 • 365 citations

Chapter 19 The determinants of stress-induced activation of the prefrontal cortical dopamine system

1991 • 361 citations

Functional differences between the prelimbic and anterior cingulate regions of the rat prefrontal cortex.

1995 • 339 citations

Prefrontal cortical regulation of hypothalamic–pituitary–adrenal function in the rat and implications for psychopathology: side matters

2002 • 316 citations

Chapter 7 Prefrontal cortical control of the autonomic nervous system: Anatomical and physiological observations

1991 • 311 citations

Functional differences between the prelimbic and anterior cingulate regions of the rat prefrontal cortex.

1995 • 293 citations

A Single Exposure to Amphetamine Is Sufficient to Induce Long-Term Behavioral, Neuroendocrine, and Neurochemical Sensitization in Rats

1999 • 286 citations

A behavioural analysis of rats with damage to the medial prefrontal cortex using the morris water maze: evidence for behavioural flexibility, but not for impaired spatial navigation

1994 • 279 citations

Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists

1995 • 263 citations

The effect of medial frontal cortex lesions on cardiovascular conditioned emotional responses in the rat

1994 • 247 citations

Normal conditioning inhibition and extinction of freezing and fear-potentiated startle following electrolytic lesions of medial prefrontal cortex in rats.

1997 • 225 citations

Frontal Brain Asymmetry as a Biological Substrate of Emotions in Patients With Panic Disorders

1999 • 224 citations

Effects of selective excitotoxic prefrontal lesions on acquisition of nonmatching‐ and matching‐to‐place in the T‐maze in the rat: differential involvement of the prelimbic–infralimbic and anterior cingulate cortices in providing behavioural flexibility

2000 • 219 citations

Modulation of anxiety-related behaviours following lesions of the prelimbic or infralimbic cortex in the rat

1997 • 216 citations

Involvement of rodent prefrontal cortex subregions in strategy switching.

1999 • 215 citations

Involvement of rodent prefrontal cortex subregions in strategy switching.

1999 • 202 citations

Prepulse inhibition and latent inhibition: the role of dopamine in the medial prefrontal cortex

1996 • 194 citations

The Effect of Medial Frontal Cortex Lesions on Respiration, “Freezing,” and Ultrasonic Vocalizations during Conditioned Emotional Responses in Rats

1991 • 180 citations

The rat medial frontal cortex projects directly to autonomic regions of the brainstem

1987 • 176 citations

Normal conditioning inhibition and extinction of freezing and fear-potentiated startle following electrolytic lesions of medial prefrontal cortex in rats.

1997 • 174 citations

Dissociation of the contributions of the prefrontal cortex and dorsomedial thalamic nucleus to spatially guided behavior in the rat

1982 • 171 citations

Functional role of rat prelimbic-infralimbic cortices in spatial memory: evidence for their involvement in attention and behavioural flexibility

2000 • 167 citations

Increased sensitivity to the sensorimotor gating-disruptive effects of apomorphine after lesions of medial prefrontal cortex or ventral hippocampus in adult rats

1995 • 166 citations

Psychological and physiological responses to stress: The right hemisphere and the hypothalamo-pituitary-adrenal axis, an inquiry into problems of human bonding

1993 • 165 citations

Differential role of the medial and lateral prefrontal cortices in fear and anxiety.

2000 • 163 citations

Differential role of the medial and lateral prefrontal cortices in fear and anxiety.

2000 • 161 citations

The effects of excitotoxic lesion of the medial prefrontal cortex on latent inhibition, prepulse inhibition, food hoarding, elevated plus maze, active avoidance and locomotor activity in the rat

1998 • 161 citations

The Prefrontal Cortex: Its Structure, Function and Pathology

1992 • 159 citations

d-Amphetamine-induced behavioral sensitization: implication of a glutamatergic medial prefrontal cortex–ventral tegmental area innervation

1999 • 156 citations

Medial prefrontal lesions in the rat and spatial navigation: Evidence for impaired planning.

1995 • 141 citations

Enhanced nucleus accumbens dopamine and plasma corticosterone stress responses in adult rats with neonatal excitotoxic lesions to the medial prefrontal cortex

2000 • 135 citations

Perinatal Distress Leads to Lateralized Medial Prefrontal Cortical Dopamine Hypofunction in Adult Rats

2000 • 131 citations

Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea‐specific lesions on drug‐induced conditioned place preference and behavioural sensitization

1999 • 131 citations

Relationships between stress-induced increases in medial prefrontal cortical dopamine and plasma corticosterone levels in rats: role of cerebral laterality

1998 • 121 citations

Medial prefrontal cortical D1 receptor modulation of the meso-accumbens dopamine response to stress: an electrochemical study in freely-behaving rats

1996 • 121 citations

Medial prefrontal lesions in the rat and spatial navigation: Evidence for impaired planning.

1995 • 108 citations

Lateralized changes in prefrontal cortical dopamine activity induced by controllable and uncontrollable stress in the rat

1993 • 107 citations

Selective dopamine depletion within the medial prefrontal cortex induces anxiogenic-like effects in rats placed on the elevated plus maze

1997 • 105 citations

Engagement in a non‐escape (displacement) behavior elicits a selective and lateralized suppression of frontal cortical dopaminergic utilization in stress

1999 • 101 citations

Serotonin laterality in amygdala predicts performance in the elevated plus maze in rats

1999 • 96 citations

Possible involvement of medial prefrontal cortex in amphetamine-induced sensitization of mesolimbic dopamine function

1995 • 95 citations

The right hemisphere and the human stress response.

1997 • 93 citations

Side and region dependent changes in dopamine activation with various durations of restraint stress

1991 • 92 citations

Effects of local infusions of dopaminergic drugs into the medial prefrontal cortex of rats on latent inhibition, prepulse inhibition and amphetamine induced activity

2000 • 87 citations

Mesial prefrontal cortical lesions and timidity in rats. I. Reactivity to aversive stimuli

1986 • 86 citations

Rat Strain Differences in the Ability to Disrupt Sensorimotor Gating Are Limited to the Dopaminergic System, Specific to Prepulse Inhibition, and Unrelated to Changes in Startle Amplitude or Nucleus Accumbens Dopamine Receptor Sensitivity

1999 • 82 citations

Asymmetrical influence of mesocortical dopamine depletion on stress ulcer development and subcortical dopamine systems in rats: Implications for psychopathology

1995 • 78 citations

Picrotoxin in the medial prefrontal cortex impairs sensorimotor gating in rats: reversal by haloperidol

1999 • 78 citations

Cytotoxic lesion of the medial prefrontal cortex abolishes the partial reinforcement extinction effect, attenuates prepulse inhibition of the acoustic startle reflex and induces transient hyperlocomotion, while sparing spontaneous object recognition memory in the rat

1999 • 76 citations

Differential Effects of Discrete Subarea-specific Lesions of the Rat Medial Prefrontal Cortex on Amphetamine- and Cocaine-induced Behavioural Sensitization

2000 • 76 citations

Medial prefrontal transection enhances social interaction

2000 • 71 citations

Cortical substrates of taste aversion learning: Dorsal prepiriform (insular) lesions disrupt taste aversion learning.

1982 • 66 citations

Dissociative effects of apomorphine infusions into the medial prefrontal cortex of rats on latent inhibition, prepulse inhibition and amphetamine-induced locomotion

1999 • 63 citations

Left and right 6-hydroxydopamine lesions of the medial prefrontal cortex differentially alter subcortical dopamine utilization and the behavioral response to stress

1996 • 62 citations

Effects of an electrolytic lesion of the prelimbic area on anxiety-related and cognitive tasks in the rat

1996 • 62 citations

Dopamine Antagonists in the Orbital Prefrontal Cortex Reduce Prepulse Inhibition of the Acoustic Startle Reflex in the Rat

1999 • 59 citations

Differential effects of pretraining inactivation of the right or left amygdala on retention of inhibitory avoidance training.

1995 • 56 citations

Differential effects of pretraining inactivation of the right or left amygdala on retention of inhibitory avoidance training.

1995 • 48 citations

Localizing Haloperidol Effects on Sensorimotor Gating in a Predictive Model of Antipsychotic Potency

1998 • 43 citations

Callosal mediation of cortical inhibition in the lateralized rat brain

1986 • 31 citations

An examination of prefrontal lesion size and the effects of cortical grafts on performance of the Morris water task by rats

1990 • 28 citations

Left and right 6-hydroxydopamine lesions of the medial prefrontal cortex differentially affect voluntary ethanol consumption

1999 • 23 citations