Extrathymic Differentiation of a T Cell Bearing Invariant Vα14Jα281 TCR

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

1978 • 1,619 citations

RAG-1 and RAG-2, Adjacent Genes That Synergistically Activate V(D)J Recombination

1990 • 1,450 citations

Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease

1991 • 1,185 citations

The V(D)J recombination activating gene, RAG-1

1989 • 1,164 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain.

1993 • 714 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

1992 • 577 citations

The T Cell Receptor as a Multicomponent Signalling Machine: CD4/CD8 Coreceptors and CD45 in T Cell Activation

1992 • 539 citations

Recognition of cluster of differentiation 1 antigens by human CD4−CD8>− cytolytic T lymphocyte

1989 • 521 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis.

1989 • 402 citations

Recognition of Self Antigens by Skin-Derived T Cells with Invariant γδ Antigen Receptors

1991 • 358 citations

Germ-line transmission of a disrupted β2microglobulin gene produced by homologous recombination in embryonic stem cells

1989 • 355 citations

The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation.

1991 • 345 citations

The Immunobiology of T Cells with Invariant gammadelta Antigen Receptors

1991 • 343 citations

A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice.

1984 • 302 citations

The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation

1989 • 301 citations

The Developmental Biology of T Lymphocytes

1988 • 300 citations

Structure, Function, and Serology of the T-Cell Antigen Receptor Complex

1987 • 264 citations

Diversity and structure of genes of the α family of mouse T-cell antigen receptor

1985 • 228 citations

Selection of Amino Acid Sequences in the Beta Chain of the T Cell Antigen Receptor

1988 • 203 citations

Unusual T cell populations in adult murine bone marrow. Prevalence of CD3+CD4-CD8- and alpha beta TCR+NK1.1+ cells.

1990 • 196 citations

V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals

1992 • 189 citations

Contribution of antigen-presenting cell major histocompatibility complex gene products to the specificity of antigen-induced T cell activation

1982 • 170 citations

Excision products of the T cell receptor gene support a progressive rearrangement model of the alpha/delta locus.

1989 • 162 citations

The Cellular Basis of T-Cell Memory

1989 • 161 citations

Site‐specific recombination in the immune system ¹

1991 • 156 citations

An unusual lineage of alpha/beta T cells that contains autoreactive cells.

1991 • 152 citations

The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria.

1991 • 145 citations

T cell receptor β gene sequences in the circular DNA of thymocyte nuclei: Direct evidence for intramolecular DNA deletion in V-D-J joining

1987 • 144 citations

In vivo persistence of expanded clones specific for bacterial antigens within the human T cell receptor alpha/beta CD4-8- subset.

1993 • 143 citations

Extrathymic development of V alpha 14-positive T cells.

1993 • 132 citations

Isolation of an excision product of T-cell receptor α-chain gene rearrangments

1987 • 124 citations

Unusual alpha beta-T cells expanded in autoimmune lpr mice are probably a counterpart of normal T cells in the liver.

1991 • 124 citations

Studies on the human T cell receptor α/β variable region genes. I. Identification of 7 additional V_α subfamilies and 14 J_α gene segments

1991 • 121 citations

Sequence and expression of transcripts of the T-cell antigen receptor alpha-chain gene in a functional, antigen-specific suppressor-T-cell hybridoma.

1986 • 118 citations

Homogenous junctional sequence of the V14+ T-cell antigen receptor alpha chain expanded in unprimed mice.

1990 • 114 citations

Dominant expression of a distinctive V14+ T-cell antigen receptor alpha chain in mice.

1991 • 101 citations

Studies of CD4- CD8- alpha beta bone marrow T cells with suppressor activity.

1992 • 82 citations

Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice.

1991 • 81 citations

Extrathymic T cell maturation. Phenotypic analysis of T cell subsets in nude mice as a function of age.

1992 • 79 citations

A new H–2-linked class I gene whose expression depends on a maternally inherited factor

1983 • 73 citations

Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor.

1989 • 71 citations

Predominant use of a particular α-chain in suppressor T cell hybridomas specific for keyhole limpet hemocyanin

1989 • 62 citations

Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200.

1986 • 61 citations

T-cell receptor variable region gene usage in T-cell populations.

1986 • 59 citations

Genetic and molecular mapping of the Hmt region of mouse.

1989 • 49 citations

Definition of a population of CD4-8- T cells that express the alpha beta T-cell receptor and respond to interleukins 2, 3, and 4.

1989 • 47 citations

Dominantly inherited expression of BID, an invariant undiversified T cell receptor δ chain

1990 • 43 citations

I–J as an idiotype of the recognition component of antigen-specific suppressor T-cell factor

1985 • 43 citations

Distinctive selection mechanisms govern the T cell receptor repertoire of peripheral CD4-CD8- alpha/beta T cells.

1992 • 43 citations

Expression of Pgp‐1 (or Ly24) by subpopulations of mouse thymocytes and activated peripheral T lymphocytes

1987 • 38 citations

Origin of autoreactive T helper cells. I. Characterization of Thy-1+, Lyt-, L3T4- precursors in the spleen of normal mice.

1986 • 35 citations

CD3+4-8- alpha beta T cell population with biased T cell receptor V gene usage. Presence in bone marrow and possible involvement of IL-3 for their extrathymic development.

1992 • 34 citations

A self-reactive T cell population that is not subject to negative selection

1992 • 34 citations

Evidence for in vivo clonal proliferation of unique population of blood CD4-/CD8- T cells bearing T-cell receptor alpha and beta chains in two normal men

1992 • 31 citations

Selection of Variable-Joining Region Combinations in the α Chain of the T Cell Receptor

1988 • 28 citations

Double-negative (CD4- CD8-) T cells with an alpha/beta T cell receptor. Non-MHC-restricted cytolytic activity and lymphokine production.

1990 • 24 citations

Autoreactive T cells in normal mice: unrestricted recognition of self peptides on dendritic cell I‐A molecules by CD4⁻CD8⁻ T cell receptor α/β⁺ T cell clones expressing V _β8.1 gene segments

1990 • 23 citations

Genetics and strain distribution of concanavalin A‐reactive Ly‐2^‐, L3T4^‐ peripheral precursors of autoreactive T cells

1988 • 20 citations

Monoclonol antibody against murine T cell receptor Vα14 cross-reacts with human CD3θ and detects disulfide-linked dimeric form

1991 • 16 citations

The Molecular Basis of MHC-Restricted Antigen Recognition by T Cells

1988 • 6 citations

Deleted Work

1955 • 0 citations