Mycotoxins: food contamination, mechanism, carcinogenic potential and preventive measures

Viral Hepatitis and Liver Disease

1985 • 1,886 citations

Fumonisins--novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme

1988 • 1,257 citations

Mycotoxins in Human and Animal Health

1977 • 1,021 citations

Research on esophageal cancer in China: a review.

1980 • 672 citations

Risk assessment of the mycotoxin ochratoxin A.

1989 • 548 citations

Aflatoxin. Scientific Background, Control and Implications

1970 • 379 citations

Worldwide Occurrence of Mycotoxins in Foods and Feeds—An Update

1989 • 348 citations

Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei

1985 • 335 citations

[Epidemiology of hepatocellular carcinoma].

1991 • 330 citations

Proceedings of an International workshop...

1996 • 328 citations

Hepatitis B virus, aflatoxins, and hepatocellular carcinoma in Southern Guangxi, China

1990 • 325 citations

Trichothecenes: Chemical, biological and toxicological aspects

1984 • 319 citations

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver.

1989 • 303 citations

Trichothecenes : chemical, biological, and toxicological aspects

1983 • 295 citations

Current situation on regulations for mycotoxins. Overview of tolerances and status of standard methods of sampling and analysis

1989 • 285 citations

Base substitution mutations induced by metabolically activated aflatoxin B1.

1983 • 278 citations

Food and beverage mycology

1981 • 272 citations

2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.

1977 • 260 citations

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver.

1978 • 246 citations

Mycotoxins in dairy products

1983 • 231 citations

Mycotoxins; production, isolation, separation and purification

1984 • 231 citations

Mycotoxins and phycotoxins

1988 • 221 citations

Aflatoxin exposure, hepatitis b virus infection and liver cancer in swaziland

1987 • 207 citations

Serum albumin adducts in the molecular epidemiology of aflatoxin carcinogenesis: correlation with aflatoxin B₁ intake and urinary excretion of aflatoxin M₁

1988 • 190 citations

Primary liver cancer and oesophageal basal cell hyperplasia in rats caused by fusarium moniliforme

1984 • 190 citations

Aflatoxin metabolism in humans: detection of metabolites and nucleic acid adducts in urine by affinity chromatography.

1985 • 185 citations

Ochratoxin A in human blood in relation to Balkan endemic nephropathy and urinary system tumours in Bulgaria

1988 • 179 citations

Site-specifically modified oligodeoxynucleotides as probes for the structural and biological effects of DNA-damaging agents

1988 • 177 citations

Ochratoxin A Carcinogenesis in the (C57BL/6J × C3H)F<sub>1</sub> Mouse<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>

1985 • 175 citations

Lipid peroxidation as a possible cause of ochratoxin a toxicity

1988 • 171 citations

Ochratoxin A in der Nahrungsmittelkette

1987 • 165 citations

Enzymes and aflatoxin biosynthesis

1988 • 158 citations

Correlation of dietary aflatoxin B1 levels with excretion of aflatoxin M1 in human urine.

1987 • 155 citations

Characterization of c-Ki-ras oncogene alleles by direct sequencing of enzymatically amplified DNA from carcinogen-induced tumors.

1987 • 135 citations

Characterization of c-Ki-ras and N-ras oncogenes in aflatoxin B1-induced rat liver tumors.

1990 • 126 citations

Sequence specificity in aflatoxin B1--DNA interactions.

1983 • 121 citations

12,13-Epoxytrichothecenes

1971 • 120 citations

Dose-related inhibition of aflatoxin B₁ induced hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene

1986 • 113 citations

Induction of renal and hepatic tumors in mice by ochratoxin A, a mycotoxin.

1978 • 112 citations

Carcinogenicity of dietary aflatoxin M1 in male Fischer rats compared to aflatoxin B1.

1987 • 109 citations

Trichothecene Mycotoxicosis Pathophysiologic Effects (1989)

2017 • 108 citations

Studies on Ochratoxins

1973 • 108 citations

Prevention of aflatoxicosis by addition of hydrated sodium calcium aluminosilicate to the diets of growing barrows.

1989 • 107 citations

Fusarin C, A Mutagen from Fusarium Moniliforme Grown on Corn

1981 • 105 citations

Moniliformin, a metabolite of Fusarium moniliforme NRRL 6322: purification and toxicity

1979 • 104 citations

Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences

1988 • 104 citations

Quantitative inter-relationships between aflatoxin B1 carcinogen dose, indole-3-carbinol anti-carcinogen dose, target organ DNA adduction and final tumor response

1989 • 101 citations

Biochemical mechanism of action of mycotoxins

1986 • 99 citations

Protective effects of 2(3)-tert-butyl-4-hydroxyanisole on chemical carcinogenesis

1986 • 98 citations

Council for Agricultural Science and Technology (CAST)

1979 • 95 citations

Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya.

1987 • 94 citations

Cardiovascular lesions and various tumors found in rats given T-2 toxin, a trichothecene metabolite of Fusarium.

1979 • 93 citations

Alteration of multiple cell membrane functions in L-6 myoblasts by T-2 toxin: An important mechanism of action

1988 • 93 citations

Aflatoxin detected in human breast milk by immunoassay

1987 • 93 citations

Mutagenic Perylenequinone Metabolites of Alternaria alternata: Altertoxins I, II, and III

1986 • 89 citations

Structure elucidation of fusarin C, a mutagen produced by Fusarium moniliforme

1984 • 85 citations

The inhibitory effects of ethoxyquin on the carcinogenic action of aflatoxin B1 in rats

1983 • 82 citations

Enzymes and aflatoxin biosynthesis.

1988 • 80 citations

Ochratoxin A contamination of cereals in an area of high incidence of Balkan endemic nephropathy in Bulgaria

1985 • 75 citations

Induction of DNA single-strand breaks by T2 toxin, a trichothecene metabolite of Fusarium

1981 • 73 citations

Mutagens produced by Alternaria alternata

1980 • 70 citations

The pathology of mycotoxins

1988 • 70 citations

A mutagenic metabolite produced by Fusarium moniliforme isolated from Linxian county, China

1985 • 65 citations

Hepatitis in vervet monkeys caused by Fusarium moniliforme

1987 • 64 citations

Epidemiology of mycotoxic porcine nephropathy.

1976 • 63 citations

Selective immunosuppression in mice of natural killer cell activity by ochratoxin A.

1987 • 63 citations

Mycotoxin teratogenicity and mutagenicity.

1981 • 61 citations

Aflatoxin as a cause of primary liver‐cell cancer in the United States: A probability study

1983 • 60 citations

Interactions of Aflatoxin B1 and Alkylating Agents with DNA: Structural and Functional Studies

1983 • 58 citations

Effect of a high affinity aluminosilicate sorbent on prevention of aflatoxicosis in growing pigs.

1989 • 56 citations

Expression of the c-Ha-ras and c-mye genes in aflatoxin B1-induced hepatocellular carcinomas

1986 • 54 citations

The effects of dietary cabbage on xenobiotic-metabolizing enzymes and the binding of aflatoxin B1 to hepatic DNA in rats

1987 • 53 citations

Natural occurrence and clastogenic effects of nivalenol, deoxynivalenol, 3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, and zearalenone in corn from a high-risk area of esophageal cancer.

1988 • 52 citations

Mycotoxins and phycotoxins

2006 • 50 citations

Enhanced metabolic activation of chemical hepatocarcinogens in woodchucks infected with hepatitis B virus

1989 • 44 citations

Production of Fusarin C by Fusarium spp

1986 • 42 citations

Distribution of aflatoxins in tissues of growing pigs fed an aflatoxin-contaminated diet amended with a high affinity aluminosilicate sorbent.

1990 • 42 citations

Suppressive and Enhancing Effect of T-2 Toxin on Murine Lymphocyte Activation and Interleukin 2 Production

1988 • 41 citations

Isolation and characterization of two new fusaric acid analogs from Fusarium moniliforme NRRL 13,163

1985 • 40 citations

Use of the isolated perfused rat liver to study carcinogen-DNA adduct formation from aflatoxin B1 and sterigmatocystin.

1980 • 33 citations

Effects of low-level long-term oral exposure to T-2 toxin in CD-1 mice

1987 • 33 citations

Genotoxic effects of a variety of sterigmatocystin-related compounds in the hepatocyte/DNA-repair test and the Salmonella microsome assay

1986 • 33 citations

Interactive effects of chemical carcinogens and hepatitis B virus in the pathogenesis of hepatocellular carcinoma.

1986 • 32 citations

Immunoassays for mycotoxins: current state of the art, commercial and epidemiological applications.

1990 • 31 citations

Metabolic activation and deactivation of fusarin C, a mutagen produced by Fusarium moniliforme

1984 • 25 citations

Effect of butylated hydroxyanisole pretreatment on aflatoxin B1-DNA binding and aflatoxin B1-glutathione conjugation in isolated hepatocytes from rats.

1989 • 23 citations

Sampling and sample preparation for detection and quantitation of natural toxicants in food and feed.

1989 • 21 citations

Proto-oncogene activation during chemically induced hepatocarcinogenesis in rodents

1989 • 21 citations

Absence of trichothecenes in toxigenic isolates of Fusarium moniliforme

1990 • 20 citations

Analysis of UK Sera for Aflatoxin by Enzyme-linked Immunosorbent Assay

1988 • 18 citations

The mycotoxicological chain and contamination of food by ochratoxin A in the nephropathic and non-nephropathic areas in Yugoslavia

1985 • 16 citations

Synthesis of nitrosomethylisoamylamine from isoamylamine and sodium nitrite by fungi

1986 • 14 citations

Sampling and Sample Preparation for Detection and Quantitation of Natural Toxicants in Food and Feed

1989 • 14 citations

Phosphoenolpyruvate carboxykinase as a selective indicator of ochratoxin A induced nephropathy.

1986 • 13 citations

Application of antibody methods to the detection of aflatoxin in human body fluids.

1988 • 11 citations

Do aflatoxin-DNA adduct measurements in humans provide accurate data for cancer risk assessment?

1988 • 10 citations

Effects of T-2 mycotoxin on tumor susceptibility in mice.

1988 • 9 citations

Structure of fusariocin C,A cytotoxic metabolite from Fusarium Moniliforme.

1981 • 8 citations

Molecular and cellular events associated with aflatoxin-induced hepatocarcinogenesis

1989 • 7 citations

Do aflatoxin-DNA adduct measurements in humans provide accurate data for cancer risk assessment?

1988 • 6 citations

Dose dependency of aflatoxin B1 binding on human high molecular weight DNA in the activation of proto-oncogene.

1985 • 6 citations

[Papilloma of forestomach induced by Fusarium T-2 toxin in mice].

1988 • 5 citations

[Mutagenicity and carcinogenicity of T-2 toxin, a trichothecene produced by Fusarium fungi].

1988 • 5 citations

STUDIES OF STERIGMATOCYSTIN (ST) PRODUCED BY ASPERGILLUS VERSICOLOR IN HUMAN GASTRIC JUICE IN VITRO

1988 • 4 citations

Dose Dependency of Aflatoxin B 1 Binding on Human High Molecular Weight DNA in The Activation of Proto-Oncogene

1985 • 3 citations

RISK EVALUATION OF OCHRATOXIN A

1988 • 2 citations

Mutagenicity and Carcinogenicity of T-2 Toxin

2017 • 2 citations

Aflatoxin in the southeastern USA

1987 • 2 citations