Enzymes and aflatoxin biosynthesis

Methods of Enzymology.

1956 • 1,750 citations

Oxygen Activation by Cytochrome P-4501

1980 • 1,013 citations

Molecular Mechanisms of Oxygen Activation

1974 • 879 citations

Handbook of Toxic Fungal Metabolites

1981 • 860 citations

Fungal metabolites II

1983 • 472 citations

Control of antibiotic biosynthesis

1980 • 469 citations

Microbial Degradation of Xenobiotics and Recalcitrant Compounds

1983 • 409 citations

Aflatoxin. Scientific Background, Control and Implications

1970 • 379 citations

The Filamentous fungi

1975 • 323 citations

Production of Aflatoxins B ₁ and G ₁ by Aspergillus flavus in a Semisynthetic Medium

1966 • 296 citations

EFFECT OF PRIMARY METABOLITES ON SECONDARY METABOLISM

1977 • 249 citations

Microbial Models of Mammalian Metabolism

1975 • 231 citations

Microbial models of mammalian metabolism. Aromatic hydroxylation

1974 • 225 citations

Microbial enzymes and bioconversions.

1980 • 199 citations

Biosynthese von 6‐Methylsalicylsäure

1970 • 183 citations

The Biosynthesis of Secondary Metabolites

1981 • 177 citations

Secondary Metabolism and Differentiation in Fungi

2020 • 177 citations

Biosynthesis of Secondary Metabolites: Roles of Trace Metals

1969 • 176 citations

Production of Aflatoxins in Submerged Culture

1965 • 168 citations

High Aflatoxin Production on a Chemically Defined Medium

1971 • 154 citations

The metabolism of aromatic acids by micro-organisms. Metabolic pathways in the fungi

1968 • 152 citations

Biosynthesis of Polyketides and Related Compounds

1967 • 149 citations

Biosynthesis of aflatoxins

1977 • 142 citations

New Perspectives on Aflatoxin Biosynthesis

1983 • 136 citations

Conversion of penicillin N to cephalosporin(s) by cell-free extracts of Cephalosporium acremonium

1976 • 122 citations

Monooxygenase activity in Cunninghamella bainieri: Evidence for a fungal system similar to liver microsomes

1973 • 103 citations

Quercetinase, a dioxygenase containing copper

1971 • 100 citations

Aryl hydrocarbon hydroxylase activity in the fungus Cunninghamella bainieri: Evidence for the presence of cytochrome P-450

1976 • 97 citations

Production of aflatoxins B1 and G1 in chemically defined medium

1967 • 97 citations

Purification and characterization of mannitol dehydrogenase from Aspergillus parasiticus

1982 • 94 citations

A Pure Enzyme Catalyzing Penicillin Biosynthesis

1984 • 92 citations

Regulation of Aflatoxin Biosynthesis: Induction of Aflatoxin Production by Various Carbohydrates

1981 • 91 citations

Aflatoxin formation, lipid synthesis, and glucose metabolism by Aspergillus parasiticus during incubation with and without agitation

1974 • 85 citations

Physiological study of ergot: induction of alkaloid synthesis by tryptophan at the enzymatic level

1976 • 85 citations

Biosynthesis of the aflatoxins

1970 • 84 citations

Regulation of secondary metabolism in fungi

1986 • 83 citations

Enzymatic Formation of Testololactone^*

1963 • 82 citations

Identification of averantin as an aflatoxin B1 precursor: placement in the biosynthetic pathway

1980 • 79 citations

6‐Methylsalicylic Acid Synthetase from Penicillium patulum

1976 • 77 citations

The chemistry of pesticides

1982 • 76 citations

Isolation of dimethylallylpyrophosphate: Tryptophan dimethylallyl transferase from the ergot fungus (Clavicepsspec.)

1971 • 75 citations

Conversion of sterigmatocystin to aflatoxin B1 by

1973 • 74 citations

Effect of specific amino acids on growth and aflatoxin production by Aspergillus parasiticus and Aspergillus flavus in defined media

1983 • 71 citations

Regulation of aflatoxin biosynthesis: effect of glucose on activities of various glycolytic enzymes

1984 • 70 citations

Synthesis of versicolorin A by a mutant strain of Aspergillus parasiticus deficient in aflatoxin production

1975 • 68 citations

Aflatoxin biosynthetic pathway: Elucidation by using blocked mutants of Aspergillus parasiticus

1977 • 68 citations

The mechanism of the microbial hydroxylation of steroids

1982 • 68 citations

De novo biosynthesis of secondary metabolism enzymes in homogeneous cultures of Penicillium urticae

1980 • 67 citations

808. Studies in mycological chemistry. Part XI. The structure of isosterigmatocystin and an amended structure for sterigmatocystin

1962 • 67 citations

A possible role of cytochrome P-450 in hydroxylation of progesterone by Rhizopus nigricans

1977 • 65 citations

Effects of Trace Metals on the Production of Aflatoxins by Aspergillus parasiticus

1975 • 64 citations

Aflatoxicok: structure of a new transformation product of aflatoxin B₁

1970 • 63 citations

Hexanoate as a starter unit in polyketide biosynthesis

1984 • 63 citations

Biosynthesis of aflatoxin B1. Conversion of versicolorin A to aflatoxin B1 by Aspergillus parasiticus

1976 • 62 citations

Isolation of orsellinic acid synthase

1968 • 61 citations

Microbial subterminal oxidation of alkanes and alk‐1‐enes

1971 • 61 citations

Nitrate Repression of Averufin and Aflatoxin Biosynthesis

1983 • 60 citations

Appearance of enzyme activities catalyzing conversion of sterigmatocystin to aflatoxin B1 in late-growth-phase Aspergillus parasiticus cultures

1987 • 59 citations

Step of Dichlorvos Inhibition in the Pathway of Aflatoxin Biosynthesis

1974 • 59 citations

Biosynthesis of aflatoxin. Conversion of norsolorinic acid and other hypothetical intermediates into aflatoxin B1

1976 • 58 citations

An Introduction to Biochemistry of Fungal Development

1976 • 58 citations

Carbon-13 nuclear magnetic resonance assignments and biosynthesis of aflatoxin B1 and sterigmatocystin

1976 • 57 citations

Mycotoxins as Secondary Metabolites

1980 • 57 citations

Steroid hydroxylation using immobilized spores of Curvularia lunata germinated in situ

1980 • 56 citations

Averufanin is an aflatoxin B1 precursor between averantin and averufin in the biosynthetic pathway

1987 • 56 citations

Enzymic Synthesis of the Aromatic Product Alternariol.

1965 • 55 citations

Aflatoxin metabolism in duck-liver homogenates: the relative importance of reversible cyclopentenone reduction and hemiacetal formation

1972 • 54 citations

Microbial secondary metabolism

1980 • 54 citations

Anhydrotetracycline oxygenase activity and biosynthesis of tetracyclines in streptomyces aureofaciens

1979 • 54 citations

Biosynthesis of the fungal xanthone ravenelin

1976 • 53 citations

Austocystins. Six novel dihydrofuro[3′,2′:4,5]furo[3,2-b]xanthenones from Aspergillus ustus

1974 • 52 citations

Biomimetic syntheses of aromatic polyketide metabolites

1986 • 52 citations

New metabolites of Aspergillus flavus

1969 • 52 citations

The Biosynthesis of Aflatoxin and Its Congeners

1980 • 51 citations

Enzymatic conversion of sterigmatocystin into aflatoxin B1 by cell-free extracts of Aspergillus parasiticus

1976 • 49 citations

Purification and kinetic characterization of mannitol-1-phosphate dehydrogenase from Aspergillus niger

1981 • 48 citations

The NIH shift during the hydroxylation of aromatic substrates by fungi

1971 • 48 citations

Patulin biosynthesis: enzymatic and nonenzymatic transformations of the mycotoxin (E)-ascladiol

1983 • 47 citations

AFLATOXIN FORMATION BY Aspergillus flavus

1969 • 46 citations

Biosynthesis of aflatoxins

1968 • 46 citations

Taxonomic studies of the aflatoxin-producing strains in the aspergillus flavus group.

1970 • 42 citations

The structure, biochemical properties and origin of the aflatoxins B2a and G2a.

1968 • 42 citations

Studies in terpenoid biosynthesis—I

1968 • 42 citations

Progress toward a biosynthetic rationale of the aflatoxin pathway

1986 • 40 citations

The relationship of cytochrome P-450 levels and alkaloid synthesis in Claviceps purpurea

1970 • 39 citations

Studies on Steroid Monooxygenase from Cylindrocarpon radicicola ATCC 110111

1986 • 39 citations

Patulin Biosynthesis: The Role of Mixed‐Function Oxidases in the Hydroxylation of m‐Cresol

1974 • 38 citations

m-Hydroxybenzyl alcohol dehydrogenase from Penicillium urticae

1972 • 38 citations

Biosynthesis of averufin by Aspergillus parasiticus; detection of 18O-label by 13C-n.m.r. isotope shifts

1980 • 38 citations

Biosynthetic relationship among aflatoxins B1, B2, M1, and M2

1985 • 38 citations

Metabolites of Aspergillus versicolor: 6,8-di-O-methylnidurufin, griseofulvin, dechlorogriseofluvin, and 3,8-dihydroxy-6-methoxy-1-methylxanthone

1976 • 37 citations

Carbon-13 nuclear magnetic resonance assignments of some fungal C20 anthraquinones; their biosynthesis in relation to that of aflatoxin B1

1977 • 37 citations

Inhibition of Aflatoxin Biosynthesis by Organophosphorus Compounds

1980 • 37 citations

Enzymatic formation of the bisfuran structure in aflatoxin biosynthesis

1980 • 36 citations

11α-hydroxylation of progesterone by cell free preparation of Aspergillus ochraceus TS

1981 • 35 citations

Secondary Metabolism and Microbial Physiology

1985 • 34 citations

Biosynthesis of echinulin. Isoprenylation of cyclo-L-alanyl-L-tryptophanyl

1972 • 34 citations

Biosynthesis of polyketides. Purification and inhibition studies of 6-methylsalicylic acid synthase

1974 • 34 citations

Studies in terpenoid biosynthesis. Part XIV. Formation of the sesquiterpene trichodiene

1976 • 34 citations

DEGRADATION OF RUTIN BY ASPERGILLUS FLAVUS: THE CARBON MONOXIDE PRODUCING SYSTEM

1963 • 33 citations

Stable isotope studies of anthraquinone intermediates in the aflatoxin pathway

1983 • 33 citations

Fungal oxidation of benzo[a]pyrene: Formation of (−)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by Cunninghamella elegans

1980 • 33 citations

Biosynthesis of mycophenolic acid

1972 • 33 citations

O-methylsterigmatocystin, a new metabolite from aspergillus flavus, link ex fries

1968 • 32 citations

Microsomal 11α-hydroxylation of progesterone in Aspergillus ochraceus: Part I: Characterization of the hydroxylase system

1982 • 32 citations

Parasiticol: new metabolite from Aspergillus parasiticus

1970 • 30 citations

The biosynthesis of a pyrone metabolite of aspergillus melleus an application of long-range 13c-13c coupling constants

1975 • 30 citations

Bisfuran formation in aflatoxin biosynthesis: the role of versiconal acetate

1982 • 30 citations

Transformation of aflatoxin B₁ by steroid-hydroxylating fungi

1969 • 28 citations

Partial characterization of the mode of action of benzoic acid on aflatoxin biosynthesis

1977 • 28 citations

Induction of polysubstrate monooxygenase and aflatoxin production by phenobarbitone in Aspergillus parasiticus NRRL 3240

1982 • 27 citations

An inducible hydrolase from Aspergillus niger, acting on carbon–carbon bonds, for phlorrhizin and other C-acylated phenols

1970 • 27 citations

Biosynthesis of slaframine, (1S,6S,8aS)-1-acetoxy-6-aminooctahydroindolizine, a parasympathomimetic alkaloid of fungal origin. I. Pipecolic acid the slaframine biogenesis

1973 • 27 citations

The fate of C-20 in C19 gibberellin biosynthesis

1978 • 27 citations

Nuclear magnetic resonance identification of versiconal hemiacetal acetate as an intermediate in aflatoxin biosynthesis

1977 • 27 citations

Enzymes Relevant to Kojic Acid Biosynthesis in Aspergillus flavus

1981 • 26 citations

Manganese and antibiotic biosynthesis. III. The site of manganese control of patulin production in Penicillium urticae

1986 • 26 citations

Relationship between Fatty‐Acid and Phenol Synthesis in Aspergillus fumigatus

1974 • 26 citations

Role of versicolorin A and its derivatives in aflatoxin biosynthesis

1982 • 26 citations

Fungal metabolism—III.

1967 • 26 citations

Metabolism of aflatoxins B1 and G1 byAspergillus parasiticus

1973 • 25 citations

The biosynthesis of the aflatoxins

1970 • 25 citations

The biosynthesis of phenols. Part XXIV. The conversion of the anthraquinone questin into the benzophenone, sulochrin, in cultures of Aspergillus terreus

1972 • 24 citations

The conversion of sterigmatocystin to O-methylsterigmatocystin and aflatoxin B1 by a cell-free preparation

1983 • 24 citations

Mutagenicity and toxicity of aflatoxin precursors

1982 • 24 citations

The use of cell free extracts derived from fungal protoplasts in the study of aflatoxin biosynthesis

1979 • 24 citations

Biosynthesis of versiconal acetate, versiconol acetate, and versiconol, metabolites from cultures of Aspergillus parasiticus treated with dichlorvos. The role of versiconal acetate in aflatoxin biosynthesis

1979 • 24 citations

Concerning the role of nidurufin in aflatoxin biosynthesis

1985 • 23 citations

Studies on the Metabolites ofAspergillus versicolor (Vuillemin) Tiraboschi

1967 • 23 citations

Untitled

1985 • 22 citations

Enzymes of secondary metabolism in microorganisms

1986 • 22 citations

THE BIOSYNTHESIS OF FUNGAL METABOLITES

1963 • 22 citations

Mechanism of aromatic hydroxylation in fungi. Evidence for the formation of arene oxides

1976 • 22 citations

Purification and characterization of glucose-6-phosphate dehydrogenase from Aspergillus parasiticus

1984 • 22 citations

Nitrogen metabolism in Aspergillus parasiticus NRRL 3240 and A. flavus NRRL 3537 in relation to aflatoxin production

1986 • 21 citations

Bisfuran formation in aflatoxin biosynthesis: the fate of the averufin side chain

1982 • 21 citations

Molecular parameters of 6-methylsalicylic acid synthetase from gel filtration and sucrose density gradient centrifugation

1968 • 21 citations

Isolation of Lipoxygenase-like Enzyme fromFusarium oxysporum

1976 • 21 citations

Carbon-13 nuclear magnetic resonance assignments and biosynthesis of versicolorin A in Aspergillus parasiticus

1978 • 20 citations

Influence of tricarboxylic acid cycle intermediates and related metabolites on the biosynthesis of aflatoxin by resting cells of Aspergillus flavus

1981 • 20 citations

Biosynthesis of patulin. Dehydrogenase and dioxygenase enzymes of penicillium patulum

1974 • 20 citations

Synthesis and absolute configuration of (+)-averufin

1985 • 20 citations

Conversion of emodin to chrysophanol in a cell-free system from Pyrenochaeta terrestris

1985 • 20 citations

Enzymic modification of environmental intoxicants: the role of cytochrome P–450

1978 • 19 citations

Cell-free biosynthesis of the tropolone ring

1962 • 19 citations

Precursor recognition by kinetic pulse-labeling in a toxigenic aflatoxin B1-producing strain of Aspergillus

1981 • 19 citations

Biosynthesis of versicolorin A

1980 • 18 citations

Mutant of Aspergillus flavus producing more aflatoxin B2 than B1

1977 • 18 citations

Activities in vitro and in vivo of enzymes of benzodiazepine alkaloid biosynthesis during development of Penicillium cyclopium

1978 • 17 citations

Biosynthetic Studies with 13C: A Novel Favorsky Rearrangement Route to the Fungal Metabolite Aspyrone

1976 • 17 citations

[40] m-Hydroxybenzyl-alcohol dehydrogenase

1975 • 17 citations

Hydroxylation of biphenyl by Aspergillus parasiticus: Approaches to yield improvment in fermenter cultures

1985 • 16 citations

[78] Immunohistological studies with monoclonal antibodies

1986 • 16 citations

A rapid method for the preparation of the three enzymes of bacitracin synthetase essentially free from other proteins

1977 • 16 citations

Effect of Halomethanes on Aflatoxin Induction in Cultures of Aspergillus parasiticus

1985 • 16 citations

Isopenicillin N epimerase activity in a high cephalosporin-producing strain of Cephalosporium acremonium

1986 • 16 citations

[38] 6-Methylsalicylic acid synthetase

1975 • 15 citations

The Structure of a New Metabolite fromAspergillus versicolor

1969 • 15 citations

A New Metabolite from Aspergillus versicolor

1973 • 15 citations

Growth temperature-dependent stearoyl coenzyme A desaturase activity of Fusarium oxysporum microsomes

1978 • 15 citations

Alternate pathways of malonylCoA formation in Streptomyces aureofaciens

1977 • 14 citations

Cyclopenin m-hydroxylase—an enzyme of alkaloid metabolism in Penicillium cyclopium

1976 • 14 citations

Biosynthesis of the aflatoxin precursor sterigmatocystin by Aspergillus versicolor; spin-echo resolution of 18O isotope shifts in 13C-n.m.r. spectroscopy

1982 • 13 citations

AN ISOPHENOXAZINE SYNTHASE FROM PYGNOPORUS COCCINEUS (FR.) BOND. AND SING.

1964 • 13 citations

Studies of polyketide chain assembly processes: incorporation of [2-13C]malonate into averufin in Aspergillus parasiticus

1987 • 13 citations

Reduction of sterigmatocystin and versicolorin A hemiacetals with sodium borohydride

1977 • 13 citations

The Biosynthesis of Patulin and Penicillic Acid

1980 • 13 citations

Activities of tricarboxylic acid cycle enzymes in an aflatoxigenic strain of Aspergillus parasiticus after a peptone to glucose carbon source shift

1985 • 13 citations

Cell-free C-Methylation in Relation to Aromatic Biosynthesis.

1969 • 13 citations

Regulation of aflatoxin biosynthesis. 2 Comparative study of tricarboxylic acid cycle in aflatoxigenic and non-aflatoxigenic strains of Aspergillus flavus.

1977 • 12 citations

Microsomal and mitochondrial involvement in production of aflatoxins induced by carbon tetrachloride and hydroperoxide in cultures of Aspergillus parasiticus

1986 • 12 citations

Structure of versicolorone isolated from Aspergillus versicolor

1982 • 12 citations

Effect of selected inhibitors on growth, pigmentation, and aflatoxin production by Aspergillus parasiticus

1986 • 12 citations

Biosynthesis of aflatoxins. Incorporation of [1,2-13C2]acetate, [2H3]acetate, and [1-13C, 2H3]acetate into sterigmatocystin in Aspergillus versicolor

1982 • 12 citations

A New Metabolite fromAspergillus versicolor

1973 • 12 citations

Pyridine nucleotides and redox state regulation of aflatoxin biosynthesis in Aspergillus parasiticus NRRL 3240

1986 • 11 citations

Dehydrocyclopeptine epoxidase from Penicillium cyclopium

1977 • 11 citations

The Crystal and Molecular Structure of Versicolorin C, A Metabolite ofAspergillus versicolor

1975 • 11 citations

Stereochemical correlation of (-)-averantin

1986 • 10 citations

The role of glycolysis in aflatoxin biosynthesis

1981 • 10 citations

Biosynthesis of secalonic acid A. The pathway indicated by a 13C nuclear magnetic resonance study of acetate incorporation

1978 • 10 citations

Isolement et structure de la deoxyaverufinone et de la dehydroaverufine: Deux metabolites de l'aspergillus versicolor (vuillemin) tiraboschi

1976 • 9 citations

Biosynthesis of mycophenolic acid. Oxidation of 6-farnesyl-5,7-dihydroxy-4-methylphthalide in a cell-free preparation from Penicillium brevicompactum

1978 • 9 citations

Microbiological transformations of terpenes. VII. Further studies on the mechanism of fungal oxygenation reactions with the aid of model substrates.

1966 • 9 citations

Formation of secondary metabolism enzymes in the tylosin producerStreptomyces T59-235

1982 • 9 citations

Oxidases in Aspergillus parasiticus in relation to aflatoxin biosynthesis

1980 • 8 citations

The Enzymic Reductions of Aryl-aldehydes and Aryl-alcohols in Penicillium baarnense.

1979 • 8 citations

[39] 6-Methylsalicylic acid (2,6-cresotic acid) decarboxylase

1975 • 8 citations

Preparation of¹⁴C‐labeled aflatoxins and incorporation of unlabeled aflatoxins in a blocked versicolorin‐A‐accumulating mutant ofaspergillus parasiticus

1981 • 8 citations

Regulation of aflatoxin biosynthesis. 1 Comparative study of mycelial composition and glycolysis in aflatoxigen and nonaflatoxigenic strains.

1977 • 8 citations

BIOENERGETICS OF AFLATOXIN BIOSYNTHESIS IN Aspergillus parasiticus

1980 • 7 citations

Transformation of aflatoxin B1 by steroid-hydroxylating fungi.-Can.

1969 • 7 citations

Conversion of emodin to physcion by a cell-free preparation of Aspergillus parasiticus

1986 • 6 citations

STUDIES ON THE PREPARATION OF CELL-FREE PROGESTERONE HYDROXYLASES FROM ASPERGILLUS NIGER 12Y

1975 • 6 citations

Formation and splitting of esters in subterminal oxidation of dodecane by Fusarium lini

1979 • 6 citations

Transformation of Steroids by Cell-free Preparations of Penicillium lilacinum NRRL 895. V. Properties of 20-Oxopregnane Side Chain Cleavage and 20(alpha+beta)-Oxidoreductase Activities.

1974 • 5 citations

Microsomal hydroxylation of phenylacetic acid by Aspergillus niger

1979 • 5 citations

NMR studies of biosynthesis and enzyme mechanism

1986 • 4 citations

Nitroaryl reductase of Aspergillus niger.

1961 • 4 citations

The Acyloin Condensation, Applied to Dimethyl Galactarate.

1969 • 3 citations

Formation and Transformation of Secondary Products — a Process of Detoxication

1984 • 2 citations

Mechanism of aromatic hydroxylation : the kinetic mechanism & the involvement of superoxide anions in the reaction catalyzed by m-hydroxybenzoate-4-hydroxylase from Aspergillus niger (UBC-814).

1978 • 2 citations

Cellular Compartmentalization and Channeling

1984 • 2 citations

Prospects for a Molecular Mycology

1985 • 2 citations

Deleted Work

1955 • 0 citations