WAY-100635 has high selectivity for serotonin 5-HT1A versus dopamine D4 receptors

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

1995 • 610 citations

Is there a role for 5-HT1A agonists in the treatment of depression?

2003 • 519 citations

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

1995 • 515 citations

The [35S]GTPγS binding assay: approaches and applications in pharmacology

2003 • 292 citations

The 5-HT1A receptor in schizophrenia: a promising target for novel atypical neuroleptics?

2001 • 214 citations

Principles: Extending the utility of [35S]GTPγS binding assays

2003 • 186 citations

Dissociable Contribution of 5-HT1A and 5-HT2A Receptors in the Medial Prefrontal Cortex to Different Aspects of Executive Control such as Impulsivity and Compulsive Perseveration in Rats

2005 • 182 citations

Estimation of competitive antagonist affinity from functional inhibition curves using the Gaddum, Schild and Cheng‐Prusoíf equations

1993 • 165 citations

WAY-100635 is a potent dopamine D4 receptor agonist

2006 • 149 citations

Characterisation of the Appearance of Radioactive Metabolites in Monkey and Human Plasma from the 5-HT1A Receptor Radioligand, [carbonyl-11C]WAY-100635—Explanation of High Signal Contrast in PET and an Aid to Biomathematical Modelling

1998 • 94 citations

Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methl-11C]WAY-100635, in monkey and human plasma by HPLC: Comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET

1996 • 92 citations

A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats

2005 • 66 citations

S 15535 and WAY 100,635 antagonise 5-HT-stimulated [35S]GTPγS binding at cloned human 5-HT1A receptors

1996 • 47 citations

A retrospect on the discovery of way-100635 and the prospect for improved 5-HT1A receptor PET radioligands

2000 • 44 citations

F15063, a potential antipsychotic with D₂/D₃ antagonist, 5‐HT_1A agonist and D₄ partial agonist properties: (I) in vitro receptor affinity and efficacy profile

2007 • 40 citations

Inverse Agonism and Constitutive Activity as Functional Correlates of Serotonin h5-HT_1BReceptor/G-Protein Stoichiometry

2000 • 37 citations

Comparative Analysis of Functional Assays for Characterization of Agonist Ligands at G Protein–Coupled Receptors

2003 • 33 citations

Pharmacological characterization of recombinant human 5-hydroxytryptamine1A receptors using a novel antagonist radioligand, [3H]way-100635

1997 • 30 citations

Differential ligand efficacy at h5-HT1A receptor-coupled G-protein subtypes: a commentary

2003 • 3 citations