WAY-100635 is a potent dopamine D4 receptor agonist

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Aripiprazole, A Novel Atypical Antipsychotic Drug with a Unique and Robust Pharmacology

2003 • 918 citations

Salvinorin A: A potent naturally occurring nonnitrogenous κ opioid selective agonist

2002 • 740 citations

A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

1995 • 610 citations

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

1995 • 515 citations

Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C]WAY-100635

1996 • 226 citations

Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic agents

1993 • 194 citations

The pharmacological characterization of a novel selective 5-hydroxytryptamine1A receptor antagonist, NAD-299.

1997 • 125 citations

First delineation of 5-HT1A receptors in human brain with PET and [11C]WAY-100635

1995 • 113 citations

Synthesis And Evaluation of 4-(2'-Methoxyphenyl)-1-[2'-[N-(2''-pyridinyl)- p-iodobenzamido]ethyl]piperazine (p-MPPI): A New Iodinated 5-HT1A Ligand

1994 • 107 citations

Sensitization of endogenous and recombinant adenylate cyclase by activation of D2 dopamine receptors.

1996 • 103 citations

Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methl-11C]WAY-100635, in monkey and human plasma by HPLC: Comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET

1996 • 92 citations

Visualisation of serotonin-1A (5-HT1A) receptors in the central nervous system

2000 • 92 citations

Short- and long-term heterologous sensitization of adenylate cyclase by D 4 dopamine receptors

1999 • 45 citations

A retrospect on the discovery of way-100635 and the prospect for improved 5-HT1A receptor PET radioligands

2000 • 44 citations

In vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, WAY-100,635 and (S)-(-)-UH-301 at rat brain monoamine receptors1Presented in part at the `9th ECNP Congress', Amsterdam, September 21–25, 1996 (Ahlenius et al., 1996).1

1999 • 18 citations

2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist

2005 • 16 citations