Multiple pathways for regulation of the KCl-induced [3H]-GABA release by metabotropic glutamate receptors, in primary rat cortical cultures

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

1997 • 3,070 citations

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

1993 • 2,272 citations

Kinetic and pharmacological properties distinguishing three types of calcium currents in chick sensory neurones.

1987 • 1,290 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle.

1987 • 767 citations

Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate

1993 • 724 citations

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4

1993 • 585 citations

Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells

1992 • 539 citations

Crosstalk between G proteins and protein kinase C mediated by the calcium channel α1 subunit

1997 • 491 citations

Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction.

1994 • 466 citations

Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus.

1991 • 431 citations

Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties

1997 • 389 citations

Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb

1993 • 355 citations

A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb

1995 • 328 citations

Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones.

1990 • 249 citations

Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors.

1994 • 246 citations

Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3

1995 • 238 citations

LY354740 is a Potent and Highly Selective Group II Metabotropic Glutamate Receptor Agonist in Cells Expressing Human Glutamate Receptors

1997 • 223 citations

L-AP4 inhibits calcium currents and synaptic transmission via a G- protein-coupled glutamate receptor

1992 • 210 citations

Cloning and Expression of Rat Metabotropic Glutamate Receptor 8 Reveals a Distinct Pharmacological Profile

1997 • 209 citations

Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary culture

1989 • 194 citations

Induction of an Olfactory Memory by the Activation of a Metabotropic Glutamate Receptor

1994 • 155 citations

Presynaptic inhibition of excitatory synaptic transmission by muscarinic and metabotropic glutamate receptor activation in the hippocampus: are Ca2+ channels involved?

1995 • 143 citations

Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord

1996 • 137 citations

L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type iv metabotropic glutamate receptor which is negatively coupled to adenylate cyclase

1992 • 135 citations

The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells

1994 • 132 citations

Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons

1993 • 126 citations

Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons

1996 • 118 citations

Metabotropic glutamate receptor-mediated suppression of L-type calcium current in acutely isolated neocortical neurons

1992 • 111 citations

2-Amino-4-phosphonobutyrate selectively blocks mossy fiber-CA3 responses in guinea pig but not rat hippocampus

1984 • 108 citations

Coupling of metabotropic glutamate receptors 2 and 4 to G alpha 15, G alpha 16, and chimeric G alpha q/i proteins: characterization of new antagonists.

1996 • 105 citations

Metabotropic glutamate receptors mGluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum

1996 • 88 citations

Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D28K

1994 • 78 citations

Localization of NMDA receptor subunit mRNAs in the rat locus coeruleus

1995 • 76 citations

A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus

1996 • 66 citations

Modulation of sensory neurone excitatory and inhibitory responses in the ventrobasal thalamus by activation of metabotropic excitatory amino acid receptors

1995 • 61 citations

A Decrease in [Ca²⁺]_c but not in cAMP Mediates L‐AP4 Inhibition of Glutamate Release: PKC‐mediated Suppression of this Inhibitory Pathway

1996 • 57 citations

Release of Endogenous Amino Acids from Striatal Neurons in Primary Culture

1986 • 57 citations

Possible presynaptic actions of 2‐amino‐4‐phosphonobutyrate in rat olfactory cortex

1987 • 42 citations

Efflux and exchange of γ-aminobutyric acid and nipecotic acid catalysed by synaptic plasma membrane vesicles isolated from immature rat brain

1983 • 42 citations

ω-Conotoxin GVIA and dihydropyridines discriminate two types of Ca2+ channels involved in GABA release from striatal neurons in culture

1990 • 39 citations

Pharmacological properties of the N-methyl-D-aspartate receptor system coupled to the evoked release of gamma-[3H] aminobutyric acid from striatal neurons in primary culture.

1990 • 32 citations

Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor.

1993 • 30 citations

The depolarization-induced outflow of d-[3H]aspartate from rat brain slices is modulated by metabotropic glutamate receptors

1994 • 29 citations

Multiple voltage-sensitive calcium channels are probably involved in endogenous GABA release from striatal neurones differentiated in primary culture

1987 • 28 citations

L-AP4 inhibits high voltage-activated Ca2+ currents in pyramidal cortical neurones

1996 • 8 citations

Novel antagonists for metabotropic glutamate receptors

1996 • 4 citations