The HLA‐DQ(α1*0102, β1*0602) heterodimer may confer susceptibility to multiple sclerosis in the absence of the HLA‐DR(α1*01, β1*1501) heterodimer

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

HLA and Disease Associations

1985 • 893 citations

HLA class II-associated genetic susceptibility in multiple sclerosis: A critical evaluation

1991 • 487 citations

HISTOCOMPATIBILITY DETERMINANTS IN MULTIPLE SCLEROSIS, WITH SPECIAL REFERENCE TO CLINICAL COURSE

1973 • 472 citations

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

1988 • 378 citations

Symptomless Cancer in Women

1964 • 367 citations

HL-A ANTIGENS AND MULTIPLE SCLEROSIS

1972 • 315 citations

Multiple Sclerosis: Association with HL—A3

1972 • 305 citations

Epidemiologic contributions to multiple sclerosis

1980 • 236 citations

Nomenclature for Factors of the HLA System, 1994

1994 • 219 citations

DQB1*0602 and DQA1*0102 (DQ1) Are Better Markers Than DR2 for Narcolepsy in Caucasian and Black Americans

1994 • 200 citations

HLA-Encoded Genetic Predisposition in IDDM: DR4 Subtypes May Be Associated With Different Degrees of Protection

1997 • 150 citations

Distribution of HLA‐DRB1, ‐DQA1 and ‐DQB1 alleles and DQA1‐DQB1 genotypes among Norwegian patients with insulin‐dependent diabetes mellitus

1991 • 144 citations

Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA‐DQ (α1*0501, (β1*02) or the HLA‐DQ (α1*03, (β1*0302) heterodimers

1997 • 137 citations

Association of susceptibility to multiple sclerosis in Sweden with HLA class II DRB1 and DQB1 alleles

1994 • 119 citations

The Data and Statistical Analysis

1985 • 102 citations

Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences

1989 • 97 citations

MULTIPLE SCLEROSIS IN NORTH-EAST SCOTLAND AN ASSOCIATION WITH HLA-DOW1

1987 • 64 citations

Nomenclature for factors of the HLA system, 1994

1994 • 56 citations

HLA matching of unrelated bone marrow transplant pairs: Direct sequencing of in vitro amplified HLA‐DRB1 and ‐DQB1 genes using magnetic beads as solid support

1993 • 53 citations

NOVEL HLA‐DR2‐RELATED HAPLOTYPES IN HONG KONG CHINESE IMPLICATE THE DQB1*0602 ALLELE IN SUSCEPTIBILITY TO MULTIPLE SCLEROSIS

1992 • 51 citations

HLA antigens in multiple sclerosis

1977 • 34 citations

Both α and β chain polymorphisms determine the specificity of the disease-associated HLA-DQ2 molecules, with β chain residues being most influential

1996 • 34 citations

PCR/oligonucleotide probe typing of HLA class II alleles in a Filipino population reveals an unusual distribution of HLA haplotypes.

1994 • 33 citations

Asian Indian HLA-DR2-, DR4-, and DR52-related DR-DQ genotypes analyzed by polymerase chain reaction based nonradioactive oligonucleotide typing unique haplotypes and a novel DR4 subtype

1994 • 31 citations

Analysis of antibody markers, DRB1, DRB5, DQA1 and DQB1 genes and modeling of DR2 molecules in DR2‐positive patients with insulin‐dependent diabetes mellitus

1994 • 30 citations

Increasing complexity of HLA-DR2 as detected by serology and oligonucleotide typing

1991 • 27 citations

Extensive study of DRB, DQA, and DQB gene polymorphism in 23 DR2-positive, insulin-dependent diabetes mellitus patients

1992 • 25 citations

HLA‐DRB1, ‐DQA1, ‐DQB1, ‐DPA1 and ‐DPB1 genes in Japanese multiple sclerosis patients

1991 • 24 citations

Multi‐locus analysis of HLA class II genes in DR2‐positive IDDM haplotypes in Finland

1994 • 21 citations

Evolutionary relationships of HLA-DR8 alleles and description of a new subtype (DRB1∗0806) in the Algerian population

1993 • 21 citations

A deletion in the second exon of an HLA-DRB1 Allele found in a DR2-negative narcolepsy patient

1993 • 8 citations

Characterization of an HLA-DR15 DQ5 haplotype found in the Spanish caucasoid population

1992 • 8 citations