Neural Grafting in Animal Models of Neurodegenerative Diseases

The hippocampus as a cognitive map

1979 • 5,527 citations

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

1983 • 3,028 citations

Spatial localization does not require the presence of local cues

1981 • 2,665 citations

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1983 • 2,149 citations

Hippocampus, space, and memory

1979 • 2,033 citations

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Brain Grafts Reduce Motor Abnormalities Produced by Destruction of Nigrostriatal Dopamine System

1979 • 963 citations

The amygdalostriatal projection in the rat—an anatomical study by anterograde and retrograde tracing methods

1982 • 884 citations

Senile dementia of the Alzheimer type

1983 • 835 citations

Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants

1979 • 830 citations

The occurrence, distribution and physiological role of catecholamines in the nervous system.

1959 • 665 citations

Presynaptic regulation of neurotransmitter release in the brain: Facts and hypothesis

1984 • 576 citations

Reinnervation of the denervated striatum by substantia nigra transplants: Functional consequences as revealed by pharmacological and sensorimotor testing

1980 • 551 citations

Neural grafting in the mammalian CNS

1985 • 536 citations

Spatial learning and motor deficits in aged rats

1984 • 509 citations

A quantitative investigation of the development of collateral reinnervation after partial deafferentation of the septal nuclei

1973 • 496 citations

Transplantation of central and peripheral monoamine neurons to the adult rat brain: Techniques and conditions for survival

1976 • 490 citations

The striatal cholinergic interneuron: Synaptic target of dopaminergic terminals?

1983 • 422 citations

Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour

1981 • 415 citations

Septal transplants restore maze learning in rats with fornix-fimbria lesions

1982 • 414 citations

Dopamine receptors localised on cerebral cortical afferents to rat corpus striatum

1978 • 401 citations

Intrahippocampal Septal Grafts Ameliorate Learning Impairments in Aged Rats

1984 • 369 citations

Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. I. Unilateral lesions

1981 • 363 citations

Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: Long‐term behavioral, biochemical, and histochemical studies

1980 • 340 citations

Efferent synaptic connections of grafted dopaminergic neurons reinnervating the host neostriatum: a tyrosine hydroxylase immunocytochemical study

1985 • 339 citations

Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions

1982 • 319 citations

Cholinergic receptor blockade impairs spatial localization by use of distal cues in the rat.

1982 • 301 citations

Cortical neuronal counts in normal elderly controls and demented patients

1983 • 293 citations

Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum

1982 • 289 citations

Reinnervation of the partially deafferented hippocampus by compensatory collateral sprouting from spared cholinergic and noradrenergic afferents

1983 • 278 citations

Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival

1985 • 271 citations

Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway

1981 • 271 citations

Reformation of the severed septohippocampal cholinergic pathway in the adult rat by transplanted septal neurons

1977 • 264 citations

Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra

1980 • 259 citations

Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path

1976 • 256 citations

Synaptic Plasticity in the Mammalian Central Nervous System

1981 • 255 citations

Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats

1984 • 246 citations

Psychobiology of the striatum

1982 • 243 citations

Functional Activity of Substantia Nigra Grafts Reinnervating the Striatum: Neurotransmitter Metabolism and [¹⁴C]2‐Deoxy‐<scp>d</scp>‐glucose Autoradiography

1982 • 234 citations

Intracerebral grafting of dissociated CNS tissue suspensions: a new approach for neuronal transplantation to deep brain sites

1981 • 230 citations

Animal Models of Declining Memory in the Aged: Short-term and Spatial Memory in the Aged Rat

1980 • 227 citations

Intracellular observations on the disinhibitory action of acetylcholine in the hippocampus

1981 • 215 citations

Movement Disorders of Aged Rats: Reversal by Dopamine Receptor Stimulation

1979 • 207 citations

Effects of scopolamine, pentobarbital, and amphetamine on radial arm maze performance in the rat

1980 • 201 citations

RESTORATION OF VISION AFTER CROSSING OF OPTIC NERVES AND AFTER CONTRALATERAL TRANSPLANTATION OF EYE

1945 • 195 citations

Functional Development of Grafted Vasopressin Neurons

1980 • 193 citations

Functional reactivation of the deafferented neostriatum by nigral transplants

1981 • 187 citations

Functional reinnervation of rat hippocampus by locus coeruleus implants

1979 • 172 citations

Iontophoretically applied dopamine depolarizes and hyperpolarizes the membrane of cat caudate neurons

1980 • 168 citations

Aged Rats: Recovery of Motor Impairments by Intrastriatal Nigral Grafts

1983 • 162 citations

Lesion-induced synaptogenesis in the dentate gyrus of aged rats: I. Loss and reacquisition of normal synaptic density

1982 • 161 citations

Electrophysiological and pharmacological characteristics of facilitation of hippocampal population spikes by stimulation of the medial septum

1982 • 160 citations

Enhanced graft survival in the hippocampus following selective denervation

1986 • 158 citations

Disinhibitory action of acetylcholine in the rat's hippocampus: Extracellular observations

1981 • 151 citations

Specific projections of retina transplanted to rat brain

1980 • 142 citations

The electrophysiology of dopamine (D2) receptors: A study of the actions of dopamine on corticostriatal transmission

1983 • 137 citations

Psychomotor performance in the senescent rodent: reduction of deficits via striatal dopamine receptor up-regulation

1983 • 135 citations

Functional correlates of compensatory collateral sprouting by aminergic and cholinergic afferents in the hippocampal formation

1983 • 125 citations

Loss of place specificity in hippocampal complex spike cells of senescent rat

1983 • 119 citations

Formation of cholinergic synapses by intrahippocampal septal grafts as revealed by choline acetyltransferase immunocytochemistry

1986 • 118 citations

Fetal mesencephalic neurons survive and extend long axons across peripheral nervous system grafts inserted into the adult rat striatum

1984 • 116 citations

Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. II. Bilateral lesions

1981 • 115 citations

Partial deafferentation of neurons in the dentate gyrus of the senescent rat

1977 • 102 citations

Dopamine and cholecystokinin immunoreactive neurones in mesencephalic grafts reinnervating the neostriatum: Evidence for selective growth regulation

1984 • 92 citations

Reactive Synaptogenesis in the Adult Nervous System

1976 • 92 citations

Cholinergic reinnervation of the rat hippocampus by septal implants is stimulated by perforant path lesion

1979 • 92 citations

Cells of origin of the ventral cholinergic septohippocampal pathway undergoing compensatory collateral sprouting following fimbria-fornix transection

1984 • 91 citations

Extensive loss of subcortical neurons in the aging rat brain

1981 • 81 citations

Transplanted septal neurons make viable cholinergic synapses with a host hippocampus

1985 • 81 citations

Role of presynaptic dopamine receptors in regulation of the glutamatergic neurotransmission in rat neostriatum

1984 • 79 citations

Deployment of optic nerve fibers is determined by positional markers in the frog's tectum☆

1974 • 71 citations

Nigral Transplants Reinnervating the Dopamine-Depleted Neostriatum Can Sustain Intracranial Self-Stimulation

1983 • 69 citations

Production of [¹⁴C]Acetylcholine and [¹⁴C]Carbon Dioxide from [U–¹⁴C]Glucose in Tissue Prisms from Aging Rat Brain

1982 • 63 citations

Retention of the original topographic polarity by the 180° rotated tectal reimplant in young adult goldfish

1973 • 60 citations

Ultrastructural evidence of synaptogenesis in the adult rat dentate gyrus from brain stem implants

1979 • 58 citations

Functional Polarization in Retinal Development and Its Reestablishment in Regenerating Retinae of Rotated Grafted Eyes.

1944 • 57 citations

Functional reactivation of the deafferented hippocampus by embryonic septal grafts as assessed by measurements of local glucose utilization

1985 • 52 citations

New Considerations in the Neuropsychology of Motivated Behaviors

1977 • 49 citations

The retinotopic organization of visual responses from tectal reimplants in adult goldfish.

1971 • 47 citations

Functional recovery following transplantation of ventral mesencephalic cells in rat subjected to 6-OHDA lesions of the mesolimbic dopaminergic neurons

1984 • 44 citations

Reciprocal transplantations between the optic tectum and the cerebellum in adult goldfish.

1979 • 40 citations

Neostriatal dopamine receptor loss and behavioral deficits in the senescent rat

1981 • 39 citations

Hippocampal deafferentation: transplantderived reinnervation and functional recovery

1982 • 35 citations