Deposition of ?/A4 protein along neuronal plasma membranes in diffuse senile plaques

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1985 • 1,425 citations

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

1990 • 1,388 citations

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

1985 • 1,025 citations

Functional plasticity of microglia: A review

1988 • 931 citations

Displacement of synaptic terminals from regenerating motoneurons by microglial cells

1968 • 845 citations

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

1990 • 735 citations

Isolation of Low‐Molecular‐Weight Proteins from Amyloid Plaque Fibers in Alzheimer's Disease

1986 • 443 citations

Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage

1989 • 345 citations

Localization of Amyloid β Protein Messenger RNA in Brains from Patients with Alzheimer's Disease

1987 • 297 citations

Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals

1988 • 270 citations

Beta-protein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease.

1989 • 241 citations

Ultrastructural Studies of the Cells Forming Amyloid Fibers in Classical Plaques

1989 • 238 citations

A4 Protein in Alzheimer's Disease: Primary and Secondary Cellular Events in Extracellular Amyloid Deposition

1989 • 236 citations

Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease.

1987 • 222 citations

Spectrum of morphological appearance of amyloid deposits in Alzheimer's disease

1989 • 219 citations

Diffuse type of senile plaques in the brains of Alzheimer-type dementia

1988 • 218 citations

The relationship between senile plaques and cerebral blood vessels in Alzheimer’s disease and senile dementia

1982 • 213 citations

Diffuse plaques do not accentuate synapse loss in Alzheimer's disease.

1990 • 209 citations

Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease.

1988 • 176 citations

Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody.

1989 • 143 citations

Electron micrograph of diffuse plaques. Initial stage of senile plaque formation in the Alzheimer brain.

1989 • 140 citations

Nephrotic glomerulonephritis.

1957 • 135 citations

A special type of senile plaque, possibly an initial stage

1987 • 129 citations

Development of senile plaques. Relationships of neuronal abnormalities and amyloid deposits.

1990 • 114 citations

Microglia in cerebellar plaques in Alzheimer's disease

1990 • 106 citations

Congophilic microangiopathy in the pathogenesis of Alzheimer's syndrome (presenile dementia)

1979 • 101 citations

Molecular pathology of amyloidogenic proteins and the role of vascular amyloidosis in Alzheimer's disease

1989 • 90 citations

EARLY SENILE PLAQUES IN DOWN'S SYNDROME BRAINS SHOW A CLOSE RELATIONSHIP WITH CELL BODIES OF NEURONS

1989 • 84 citations

Differential brain expression of the Alzheimer's amyloid precursor protein.

1989 • 75 citations

AN ANALYSIS OF THE MORPHOLOGY OF SENILE PLAQUES IN DOWN'S SYNDROME PATIENTS OF DIFFERENT AGES USING IMMUNOCYTOCHEMICAL AND LECTIN HISTOCHEMICAL TECHNIQUES

1989 • 74 citations

Immunoelectron microscopic localization of amyloid β protein in the diffuse plaques of Alzheimer-type dementia

1990 • 69 citations

Synaptophysin and chromogranin A immunoreactivities in senile plaques of Alzheimer's disease

1991 • 68 citations

Alzheimer patients and Down patients: Abnormal presynaptic terminals are related to cerebral preamyloid deposits

1990 • 55 citations

Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimerʼs disease

1988 • 39 citations

Neuronal Origin of Cerebral Amyloidogenic Proteins: Their Role in Alzheimer's Disease and Unconventional Virus Diseases of the Nervous System

2007 • 12 citations

Concurrence of Limb Girdle Muscular Dystrophy and Myasthenia Gravis

1989 • 11 citations

HISTOGENESIS OF SENILE PLAQUES

1941 • 10 citations