Timing Requirements for Insulin/IGF-1 Signaling in C. elegans

A C. elegans mutant that lives twice as long as wild type

1993 • 3,250 citations

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

2001 • 1,779 citations

A Mutant Drosophila Insulin Receptor Homolog That Extends Life-Span and Impairs Neuroendocrine Function

2001 • 1,583 citations

Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein

2001 • 1,398 citations

Genetic pathways that regulate ageing in model organisms

2000 • 1,341 citations

Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

2000 • 909 citations

A Role for the RNase III Enzyme DCR-1 in RNA Interference and Germ Line Development in Caenorhabditis elegans

2001 • 853 citations

Genetic Analysis of Tissue Aging in Caenorhabditis elegans: A Role for Heat-Shock Factor and Bacterial Proliferation

2002 • 774 citations

Two Pleiotropic Classes of daf-2 Mutation Affect Larval Arrest, Adult Behavior, Reproduction and Longevity in Caenorhabditis elegans

1998 • 691 citations

The Caenorhabditis elegans dauer larva: Developmental effects of pheromone, food, and temperature

1984 • 594 citations

Genes that regulate both development and longevity in Caenorhabditis elegans.

1995 • 579 citations

A Conserved Regulatory System for Aging

2001 • 526 citations

FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies

1999 • 462 citations

daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans.

1994 • 375 citations

Induced Overexpression of Mitochondrial Mn-Superoxide Dismutase Extends the Life Span of Adult Drosophila melanogaster

2002 • 374 citations

An Insulin-like Signaling Pathway Affects Both Longevity and Reproduction in Caenorhabditis elegans

1998 • 347 citations

Insulin/IGF signalling and ageing: seeing the bigger picture

2001 • 174 citations

Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans

2001 • 154 citations

Delayed Aging in Ames Dwarf Mice. Relationships to Endocrine Function and Body Size

2000 • 106 citations

Stress Response and Aging in Caenorhabditis elegans

2000 • 30 citations