Lens proteins are substrates for the reticulocyte ubiquitin conjugation system

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

1983 • 1,105 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells: Part 2

1976 • 1,060 citations

Proteinases in mammalian cells and tissues

1978 • 981 citations

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.

1980 • 727 citations

Mechanisms of Intracellular Protein Breakdown

1982 • 647 citations

Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1984 • 533 citations

ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation.

1980 • 530 citations

Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes.

1980 • 393 citations

Clonal stability and phenotypic expression of chick cartilage cells in vitro.

1966 • 322 citations

Ubiquitin: Roles in protein modification and breakdown

1983 • 297 citations

The ubiquitin‐mediated proteolytic pathway and mechanisms of energy‐dependent intracellular protein degradation

1984 • 221 citations

Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP.

1979 • 210 citations

Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells.

1982 • 128 citations

Ubiquitin-lysozyme conjugates. Purification and susceptibility to proteolysis.

1986 • 108 citations

The eye lens has an active ubiquitin-protein conjugation system.

1986 • 94 citations

The inactivation of ubiquitin accounts for the inability to demonstrate ATP, ubiquitin-dependent proteolysis in liver extracts.

1985 • 77 citations

Identification and quantification of leucine aminopeptidase in aged normal and cataractous human lenses and ability of bovine lens LAP to cleave bovine crystallins

1982 • 69 citations

Actin binding proteins of the brush border

1983 • 62 citations

Limited proteolysis of bovine lens α-crystallin by calpain, A Ca2+-dependent cysteine proteinase, isolated from the same tissue

1984 • 60 citations

Comparison of leucine aminopeptidase from human lens, beef lens and kidney, and hog lens and kidney

1984 • 42 citations

Evidence for a calcium activated protease specific for lens intermediate filaments

1984 • 34 citations

Isolation and characterization of a 25K serine proteinase from bovine lens cortex

1983 • 33 citations

Changes during aging in rat lens endopeptidase activity

1984 • 29 citations

Localization of leucine aminopeptidase in normal hog lens by immunofluorescence and activity assays.

1983 • 28 citations

Establishment of epithelial cell lines from individual rabbit lenses

1980 • 26 citations

Prognostic value of laser interferometric visual acuity in amblyopia therapy.

1986 • 16 citations

Differential inhibition of two proteolytic activities in bovine lens neutral-proteinase preparations

1985 • 13 citations

Establishment and characterization of a lens epithelial cell line from an eight year old rabbit

1982 • 11 citations