Detection of antimitochondrial autoantibodies in immunofluorescent AMA-negative patients with primary biliary cirrhosis using recombinant autoantigens

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system

1991 • 794 citations

Identification and specificity of a cDNA encoding the 70 kd mitochondrial antigen recognized in primary biliary cirrhosis.

1987 • 557 citations

SEROLOGICAL TESTS IN DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS

1965 • 504 citations

Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: dihydrolipoamide acetyltransferase.

1988 • 259 citations

Autoimmune cholangiopathy: Part of the spectrum of autoimmune chronic active hepatitis

1993 • 219 citations

Detection of Autoantibodies to Recombinant Mitochondrial Proteins in Patients with Primary Biliary Cirrhosis

1989 • 206 citations

Comparison of the Clinicopathologic Features of Primary Sclerosing Chol-angitis and Primary Biliary Cirrhosis

1985 • 196 citations

Antimitochondrial antibody-negative primary biliary cirrhosis.

1995 • 183 citations

Structural requirement for autoreactivity on human pyruvate dehydrogenase-E2, the major autoantigen of primary biliary cirrhosis. Implication for a conformational autoepitope.

1990 • 173 citations

Use of a designer triple expression hybrid clone for three different lipoyl domain for the detection of antimitochondrial autoantibodies

1996 • 148 citations

Primary Biliary Cirrhosis Showing a High Titer of Autoantibody

1958 • 144 citations

Epitope mapping and reactivity of autoantibodies to the E2 component of 2-oxoglutarate dehydrogenase complex in primary biliary cirrhosis using recombinant 2-oxoglutarate dehydrogenase complex

1996 • 133 citations

Reactivity of primary biliary cirrhosis sera with a human fetal liver cDNA clone of branched-chain α-keto acid dehydrogenase dihydrolipoamide acyltransferase, the 52 kD mitochondrial autoantigen

1989 • 110 citations

Autoimmune cholangiopathy: The result of consecutive primary biliary cirrhosis and autoimmune hepatitis?

1994 • 109 citations

Frequency of IgG and IgM autoantibodies to four specific M2 mitochondrial autoantigens in primary biliary cirrhosis

1989 • 102 citations

Conservation of primary structure in the lipoyl-bearing and dihydrolipoyl dehydrogenase binding domains of mammalian branched-chain .alpha.-keto acid dehydrogenase complex: molecular cloning of human and bovine transacylase (E2) cDNAs

1988 • 80 citations

Pathology and Immunopathology of Primary Biliary Cirrhosis With Emphasis On Bile Duct Lesions: Recent Progress

1995 • 63 citations

Autoimmune Cholangitis: A Unique Entity?

1998 • 43 citations

Ludwig Symposium on biliary disorders. Autoimmune cholangitis: a unique entity?

1998 • 34 citations

High prevalence of anti-mitochondrial antibodies among patients with some well-defined connective tissue diseases.

1986 • 30 citations

Antimitochondrial (pyruvate dehydrogenase) antibodies in leprosy

1994 • 28 citations

Specific reactivity of recombinant human PDC-E1α in primary biliary cirrhosis

1991 • 24 citations

Isolation, characterization, and mapping of gene encoding dihydrolipoyl succinyltransferase (E2k) of humanα-ketoglutarate dehydrogenase complex

1994 • 20 citations

Serial changes of serum anti-M2 proteins in patients with primary biliary cirrhosis: a follow-up study by immunoblotting

1999 • 14 citations

False positive reaction in ELISA for IgM class anti-M2 antibody and its prevention

2001 • 13 citations

Detection of Anti-branched Chain 2-0xo Acid Dehydrogenase Complex (BCOADC)-E2 Antibody in Primary Biliary Cirrhosis by ELISA using Recombinant Fusion Protein

1999 • 11 citations

Combination assays for IgG class and IgM class anti-pyruvate dehydrogenase complex(PDC)-E2 by ELISA using recombinant autoantigen to diagnose primary biliary cirrhosis

1998 • 10 citations

Serial changes in enzyme inhibitory antibody to pyruvate dehydrogenase complex during the course of primary biliary cirrhosis

2000 • 9 citations

Distribution of the PBC-specific- (M2) and the naturally-occurring mitochondrial antigen- (NOMAg) systems in plants

1992 • 3 citations

Immunoreactivity of recombinant human oxo-glutarate dehydrogenase complex (OGDC)-E2 protein in primary biliary cirrhosis

2000 • 3 citations