Conservation of primary structure in the lipoyl-bearing and dihydrolipoyl dehydrogenase binding domains of mammalian branched-chain .alpha.-keto acid dehydrogenase complex: molecular cloning of human and bovine transacylase (E2) cDNAs

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Analysis of membrane and surface protein sequences with the hydrophobic moment plot

1984 • 2,234 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Purification and characterization of branched chain α-keto acid dehydrogenase complex of bovine kidney

1978 • 280 citations

The Pyruvate Dehydrogenase Complex of Escherichia coli K12

1983 • 229 citations

Isolation of rabbit liver branched chain alpha-ketoacid dehydrogenase and regulation by phosphorylation.

1982 • 172 citations

Nucleotide sequence of the sucB gene encoding the dihydrolipoamide succinyltransferase of Escherichia coli K12 and homology with the corresponding acetyltransferase

1984 • 141 citations

Self-assembly and catalytic activity of the pyruvate dehydrogenase multienzyme complex of Escherichia coli

1977 • 137 citations

Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from Escherichia coli

1979 • 122 citations

Genetic reconstruction and functional analysis of the repeating lipoyl domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

1985 • 120 citations

Regulation of the branched chain 2‐oxoacid dehydrogenase kinase reaction

1982 • 116 citations

Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA

1987 • 110 citations

Acyl group and electron pair relay system: A network of interacting lipoyl moieties in the pyruvate and α-ketoglutarate dehydrogenase complexes from Escherichia coli

1977 • 108 citations

Purification of rat kidney branched-chain oxo acid dehydrogenase complex with endogenous kinase activity

1982 • 102 citations

Mobility of polypeptide chain in the pyruvate dehydrogenase complex revealed by proton NMR

1981 • 101 citations

Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from bovine heart.

1981 • 100 citations

Purification and properties of branched-chain alpha-keto acid dehydrogenase phosphatase from bovine kidney.

1984 • 100 citations

α-Keto Acid Dehydrogenase Complexes

1973 • 96 citations

Repeating functional domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli.

1984 • 83 citations

Rapid intersite transfer of acetyl groups and movement of pyruvate dehydrogenase component in the kidney pyruvate dehydrogenase complex.

1980 • 75 citations

Chain folding in the dihydrolipoyl acyltransferase components of the 2‐oxo‐acid dehydrogenase complexes from Escherichia coli

1986 • 71 citations

Identification of specific subunits of highly purified bovine liver branched-chain ketoacid dehydrogenase

1983 • 66 citations

Resolution and reconstitution of bovine kidney branched-chain 2-oxo acid dehydrogenase complex

1985 • 57 citations

Limited proteolysis and sequence analysis of the 2-oxo acid dehydrogenase complexes from Escherichia coli. Cleavage sites and domains in the dihydrolipoamide acyltransferase components

1987 • 53 citations

Molecular cloning of genes encoding branched-chain keto acid dehydrogenase of Pseudomonas putida

1987 • 44 citations

Limited proteolysis and proton n.m.r. spectroscopy of the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli

1981 • 42 citations

Dephosphorylation and reactivation of phosphorylated purified ox‐kidney branched‐chain dehydrogenase complex by co‐purified phosphatase

1983 • 41 citations

Primary structure around the lipoate-attachment site on the E2 component of bovine heart pyruvate dehydrogenase complex

1987 • 39 citations

Catalytic and structural properties of the dihydrolipoyl transacylase component of bovine branched-chain alpha-keto acid dehydrogenase.

1984 • 39 citations

Induction of the branched-chain 2-oxo acid dehydrogenase complex in 3T3-L1 adipocytes during differentiation

1983 • 38 citations

Subunit structure of the dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Characterization of the inner transacylase core.

1985 • 36 citations

Primary structure of the swinging arms of the pyruvate dehydrogenase complex of Escherichia coli

1979 • 32 citations

Protein Mobility Inside Pyruvate Dehydrogenase Complexes as Reflected by Laser‐Pulse Fluorometry

1980 • 26 citations

Conformational mobility of polypeptide chains in the 2‐oxo acid dehydrogenase complexes from ox heart revealed by proton NMR spectroscopy

1981 • 23 citations

Subunit structure of the dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Mapping of the lipoyl-bearing domain by limited proteolysis.

1986 • 21 citations

Identification of a cDNA clone in λgt11 for the transacylase component of branched chain ketoacid dehydrogenase

1985 • 20 citations

Purification and characterization of human liver branched-chain α-keto acid dehydrogenase complex

1987 • 17 citations

Nuclear-magnetic-resonance spectroscopy studies of the flexible linkages between lipoyl domains in the pyruvate dehydrogenase multienzyme complex from Escherichia coli

1986 • 11 citations

Localization of lipoyl-bearing domains in the .alpha.-ketoglutarate dehydrogenase multienzyme complex

1984 • 10 citations