Inhibition of angiotensin converting enzyme: mechanism and substrate dependence

The determination of enzyme inhibitor constants

1953 • 4,050 citations

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

1977 • 1,851 citations

Renin-angiotensin system: biochemistry and mechanisms of action.

1977 • 1,373 citations

A Schematic Method of Deriving the Rate Laws for Enzyme-Catalyzed Reactions

1956 • 994 citations

Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids

1977 • 900 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆II. Inhibition: Nomenclature and theory

1963 • 865 citations

A new class of angiotensin-converting enzyme inhibitors

1980 • 704 citations

[17] The kinetics of reversible tight-binding inhibition

1979 • 679 citations

Antihypertensive Effect of the Oral Angiotensin Converting-Enzyme Inhibitor SQ 14225 in Man

1978 • 612 citations

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

1972 • 524 citations

The slow-binding and slow, tight-binding inhibition of enzyme-catalysed reactions

1982 • 488 citations

Angiotensin-Converting Enzyme and the Regulation of Vasoactive Peptides

1976 • 457 citations

THE EXISTENCE OF TWO FORMS OF HYPERTENSIN

1954 • 426 citations

A continuous spectrophotometric assay for angiotensin converting enzyme

1979 • 416 citations

Conversion of angiotensin I to angiotensin II

1976 • 211 citations

ANTIHYPERTENSIVE EFFECT OF THE NEW ORAL ANGIOTENSIN CONVERTING ENZYME INHIBITOR "MK-421".

1981 • 189 citations

Tight-binding inhibitors—III

1976 • 132 citations

Substrate specificity and kinetic characteristics of angiotensin converting enzyme

1983 • 113 citations

Activation of angiotensin converting enzyme by monovalent anions

1983 • 107 citations

2 Inhibitiors of Angiotensin-Converting Enzyme

1980 • 105 citations

Synthesis and biological activity of a ketomethylene analog of a tripeptide inhibitor of angiotensin converting enzyme

1980 • 93 citations

Inhibition of angiotensin-converting enzyme by analogs of peptides fromBothrops jararaca venom

1973 • 90 citations

Anion activation of angiotensin converting enzyme: dependence on nature of substrate

1983 • 82 citations

Metal-coordinating substrate analogs as inhibitors of metalloenzymes.

1979 • 81 citations

Affinity chromatographic purification of angiotensin converting enzyme

1984 • 78 citations

Phosphorus-containing inhibitors of angiotensin-converting enzyme.

1982 • 52 citations

Kinetic properties of pulmonary angiotensin-converting enzyme. Hydrolysis of hippurylglycylglycine

1976 • 46 citations

Inhibition of angiotensin converting enzyme by phosphonic amides and phosphonic acids

1983 • 42 citations

Inhibition of angiotensin converting enzyme with Nα-phosphoryl-L-alanyl-L-proline and Nα-phosphoryl-L-valyl-L-tryptophan

1980 • 27 citations

Multiple inhibitor binding to arsanilazotyrosine-248 carboxypeptidase A

1978 • 21 citations

Complex Competitive and Non-Competitive Inhibition of Rat Lung Angiotensin-Converting Enzyme by Inhibitors Containing Thiol Groups: Captopril and SA 446

1981 • 16 citations

Inhibition of angiotensin-converting enzym by derivaties of 3-mercapto-2-methyloropanoyl glycine

1983 • 6 citations

PLATES OF ARTERIES.

1834 • 1 citations