Effects of tolbutamide on fructose-2,6-bisphosphate formation and ketogenesis in hepatocytes from diabetic rats

Chapter 4 Preparation of Isolated Rat Liver Cells

1976 • 5,335 citations

Enzymic determination of <scp>d</scp>(−)-β-hydroxybutyric acid and acetoacetic acid in blood

1962 • 1,407 citations

Fructose 2,6-bisphosphate, the probably structure of the glucose- and glucagon-sensitive stimulator of phosphofructokinase

1980 • 309 citations

Inhibition of fructose-1,6-bisphosphatase by fructose 2,6-bisphosphate.

1981 • 239 citations

Fructose 2,6-bisphosphate. A new activator of phosphofructokinase.

1981 • 207 citations

The Effect of Chronic Sulfonylurea Therapy on Hepatic Glucose Production in Non-insulin-dependent Diabetes

1982 • 138 citations

Fructose-2,6-P2, chemistry and biological function

1982 • 115 citations

The Role of Fructose 2,6-Bisphosphate in the Regulation of Carbohydrate Metabolism

1984 • 115 citations

An activation factor of liver phosphofructokinase.

1980 • 97 citations

Induction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA by refeeding and insulin.

1988 • 95 citations

Synthesis of a stimulator of phosphofructokinase, most likely fructose 2,6-bisphosphate, from phosphoric acid and fructose 6-phosphoric acid

1980 • 95 citations

Changes in the concentration of activation factor for phosphofructokinase in hepatocytes in response to glucose and glucagon

1980 • 77 citations

The action of insulin on hepatic fructose 2,6-bisphosphate metabolism.

1983 • 77 citations

Cyclic AMP-dependent phosphorylation of rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase

1982 • 75 citations

Effect of Diabetes, Insulin, Starvation, and Refeeding on the Level of Rat Hepatic Fructose 2,6-Bisphosphate

1981 • 68 citations

Modulation by a Sulfonylurea of Insulin-dependent Glycogenesis, but Not of Insulin Binding, in Cultured Rat Hepatocytes: Evidence for a Postreceptor Mechanism of Action

1984 • 67 citations

The hypoglycemic sulfonylureas glyburide and tolbutamide inhibit fatty acid oxidation by inhibiting carnitine palmitoyltransferase.

1987 • 50 citations

The effect of chronic sulfonylurea therapy on hepatic glucose production in non-insulin-dependent diabetes

1982 • 44 citations

Tolbutamide Stimulates Fructose-2, 6-Bisphosphate Formation in Perfused Rat Liver

1984 • 44 citations

Effect of tolbutamide on myocardial energy metabolism

1983 • 39 citations

Sulfonylurea stimulates liver fructose-2,6-bisphosphate formation in proportion to its hypoglycemic action

1985 • 31 citations

ACUTE TOLBUTAMIDE ADMINISTRATION ALONE OR COMBINED WITH INSULIN ENHANCES GLUCOSE INTAKE IN THE PERFUSED RAT HINDLIMB

1982 • 31 citations

Hepatic Effects of Chlorpropamide: Inhibition of Glucagon-stimulated Gluconeogenesis in Perfused Livers of Fasted Rats

1979 • 30 citations

An effect of tolbutamide on ketogenesis, in vivo and in vitro.

1960 • 28 citations

Effect of Tolbutamide on Myocardial Metabolism and Mechanical Performance of the Diabetic Rat

1984 • 27 citations

Portal and Peripheral Vein Immunoreactive Insulin Concentrations Following Tolbutamide Administration

1971 • 24 citations

Immunoreactive Insulin in the Portal and the Peripheral Venous Blood after Intravenous Tolbutamide Administration

1971 • 23 citations

Effect of tolbutamide on fructose-6-phosphate, 2-kinase and fructose-2, 6-bisphosphatase in rat liver

1986 • 21 citations

Effect of glipizide on hepatic fructose 2,6-bisphosphate concentration and glucose metabolism

1987 • 19 citations

Modulation by a sulfonylurea of insulin-dependent glycogenesis, but not of insulin binding, in cultured rat hepatocytes. Evidence for a postreceptor mechanism of action

1984 • 19 citations

Effect of tolbutamide on myocardial metabolism and mechanical performance of the diabetic rat

1984 • 17 citations

Effect of diabetes, insulin, starvation, and refeeding on the level of rat hepatic fructose 2,6-bisphosphate

1981 • 17 citations

Hepatic effects of chlorpropamide: inhibition of glucagon-stimulated gluconeogenesis in perfused livers of fasted rats

1979 • 16 citations

Effect of sulfonylureas on hepatic fatty acid oxidation

1986 • 15 citations

Tolbutamide stimulates fructose-2, 6-bisphosphate formation in perfused rat liver

1984 • 15 citations

Effects of tolbutamide on gluconeogenesis and glycolysis in isolated perfused rat liver

1986 • 13 citations

Effect of Tolazamide on Basal Ketogenesis, Glycogenesis, and Gluconeogenesis in Liver Obtained from Normal and Diabetic Rats*

1986 • 13 citations

Profile of Insulin Release Due to Intrapancreatic Glyburide Infusion

1972 • 13 citations

Metabolic effects of hypoglycemic sulfonylureas—III

1974 • 12 citations

Sulfonylurea Enhances Insulin-Induced Acetyl Coenzyme A Carboxylase Activity in Rat Adipocytes

1991 • 7 citations

The inhibitory effect of sulphonylurea derivatives on liver glycogenosis increased by catecholamines

1970 • 6 citations

Evidence that Insulin Deficiency in the Rat Has Disparate Effects on Fructose 2,6-Bisphosphate Levels in Muscle and Liver*

1986 • 6 citations