Clinical Pharmacokinetics of Molsidomine

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Molsidomine in the Treatment of Patients with Angina Pectoris

1980 • 102 citations

Nitric oxide and nitrovasodilators: Similarities, differences and potential interactions

1994 • 93 citations

The Role of Nitrates in Coronary Heart Disease

1995 • 71 citations

Biotransformation of Molsidomine (N-Ethoxycarbonyl-3-morpholinosydnonimine), a New Anti-anginal Agent, in Rats

1974 • 47 citations

METABOLIC FATE OF 5-ETHOXYCARBONYL-3-MORPHOLINOSYDNONIMINE (SIN-10)

1970 • 35 citations

Relationship between pharmacokinetics and pharmacodynamics of molsidomine and its metabolites in humans

1985 • 29 citations

The mode of hypotensive action of newly synthesized sydnonimine derivatives.

1971 • 28 citations

Determination of molsidomine in plasma by high-performance liquid column chromatography

1978 • 24 citations

Hemodynamic Response to Molsidomine in Patients with Ischemic Cardiomyopathy Tolerant to Isosorbide Dinitrate

1991 • 20 citations

Comparison of the hemodynamic responses to molsidomine and isosorbide dinitrate in congestive heart failure

1994 • 15 citations

The metabolism of [¹⁴C]N-ethoxycarbonyl-3-morpholinosydnonimine (molsidomine) in man

1987 • 11 citations

Liver function and pharmacokinetics of molsidomine and its metabolite 3-morpholinosydnonimine in healthy volunteers.

1986 • 11 citations

Intravenous and oral administration of molsidomine, a pharmacodynamic and pharmacokinetic study

1984 • 10 citations

The effect of different nitrate preparations on plasma heparin concentrations and the activated partial thromboplastin time

1994 • 8 citations

[Human pharmacokinetics of molsidomine].

1983 • 7 citations

Hemodynamic effects of SIN-1 in acute left heart failure

1989 • 7 citations

Pharmacokinetics of molsidomine and its active metabolite, linsidomine, in patients with liver cirrhosis.

1991 • 7 citations

Pharmacokinetics and pharmacodynamics of molsidomine in patients with liver dysfunction due to congestive heart failure.

1992 • 4 citations

[Molsidomin in coronary disease. Clinico-pharmacokinetic correlation study on the effect of oral and sublingual therapy].

1983 • 4 citations

Comparative study of the haemodynamic effects of oral molsidomine and isosorbide dinitrate in man

1982 • 4 citations

Pharmacokinetics of molsidomine and of its active metabolite, SIN‐1 (or linsidomine), in the elderly

1991 • 2 citations

Pharmacokinetics of linsidomine (SIN 1) after single and multiple intravenous short infusions in patients with renal insufficiency.

1993 • 2 citations

[Comparison of oral and intravenous administration of molsidomine in patients with heart failure].

1994 • 1 citations