MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1995 • 5,143 citations

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals

1999 • 2,076 citations

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

1994 • 1,802 citations

Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

1996 • 1,253 citations

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activationofCREB

1998 • 975 citations

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

1999 • 970 citations

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

1994 • 732 citations

Nerve Growth Factor Activates Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Pathways To Stimulate CREB Serine 133 Phosphorylation

1998 • 495 citations

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

2000 • 487 citations

Glutamate Induces Phosphorylation of Elk-1 and CREB, Along with c -fos Activation, via an Extracellular Signal-Regulated Kinase-Dependent Pathway in Brain Slices

1999 • 310 citations

Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein

1998 • 302 citations

Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c- fos gene

1998 • 302 citations

Transcriptional regulation by cyclic AMP-responsive factors

2000 • 228 citations

Production of targeted embryonic stem cell clones

1999 • 204 citations

Role of Mitogen-Activated Protein Kinase Cascades in Mediating Lipopolysaccharide-Stimulated Induction of Cyclooxygenase-2 and IL-1β in RAW264 Macrophages

2000 • 204 citations

RSK-B, a Novel Ribosomal S6 Kinase Family Member, Is a CREB Kinase under Dominant Control of p38α Mitogen-activated Protein Kinase (p38αMAPK)

1998 • 164 citations

Role of protein kinase B and the MAP kinase cascade in mediating the EGF‐dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells¹

1999 • 89 citations

Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c- Fos gene

2000 • 74 citations

Cloning and Characterization of RLPK, a Novel RSK-related Protein Kinase

1999 • 52 citations