Crystal structure of Escherichia coli RNase HI in complex with Mg²⁺ at 2.8 Å resolution: Proof for a single Mg²⁺‐binding site

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.

1991 • 1,059 citations

Stereochemically restrained refinement of macromolecular structures

1985 • 614 citations

Origins and Evolutionary Relationships of Retroviruses

1989 • 581 citations

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

1991 • 566 citations

Retroviruses

1988 • 512 citations

Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H.

1980 • 496 citations

Structure of Ribonuclease H Phased at 2 Å Resolution by MAD Analysis of the Selenomethionyl Protein

1990 • 475 citations

Three-dimensional structure of ribonuclease H from E. coli

1990 • 348 citations

Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA

1986 • 327 citations

Cocrystal structure of an editing complex of Klenow fragment with DNA.

1988 • 324 citations

A method of positioning a known molecule in an unknown crystal structure

1967 • 272 citations

X-ray structure of the DNase I-d(GGTATACC)2 complex at 2·3Å resolution

1992 • 248 citations

X-ray diffraction data collection system for modern protein crystallography with a Weissenberg camera and an imaging plate using synchrotron radiation

1991 • 230 citations

Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution

1992 • 228 citations

Isolation and Characterization of an Endonuclease from Escherichia coli Specific for Ribonucleic Acid in Ribonucleic Acid·Deoxyribonucleic Acid Hybrid Structures

1973 • 223 citations

How does RNase H recognize a DNA.RNA hybrid?

1991 • 188 citations

Identification of the amino acid residues involved in an active site of Escherichia coli ribonuclease H by site-directed mutagenesis.

1990 • 176 citations

Isolation and characterization of a second RNase H (RNase HII) of Escherichia coli K-12 encoded by the rnhB gene.

1990 • 141 citations

Multiple mechanisms for initiation of ColE1 DNA replication: DNA synthesis in the presence and absence of ribonuclease H

1987 • 129 citations

Crystal Structure of Ribonuclease H from Thermus thermophilus HB8 Refined at 2·8 Å Resolution

1993 • 119 citations

The processing of diffraction data taken on a screenless Weissenberg camera for macromolecular crystallography

1989 • 119 citations

Three-dimensional structure of bovine pancreatic DNase I at 2.5 A resolution.

1984 • 110 citations

Role of histidine 124 in the catalytic function of ribonuclease HI from Escherichia coli.

1993 • 82 citations

On the catalytic mechanism of EcoRI and EcoRV A detailed proposal based on biochemical results, structural data and molecular modelling

1992 • 67 citations

RNase H-defective mutants of Escherichia coli: A possible discriminatory role of RNase H in initiation of DNA replication

1984 • 67 citations

A group refinement procedure in protein crystallography using Fourier transforms

1985 • 47 citations

Binding of metal ions toE. coli RNase HI observed by1H−15N heteronuclear 2D NMR

1991 • 39 citations

Crystal structures of ribonuclease HI active site mutants from Escherichia coli.

1993 • 36 citations