Role of glandular kallikreins as growth factor processing enzymes: Structural and evolutionary considerations

Handbook of experimental pharmacology

1971 • 526 citations

Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor

1983 • 520 citations

Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs.

1984 • 519 citations

Human β-nerve growth factor gene sequence highly homologous to that of mouse

1983 • 486 citations

Biologically active polypeptides in submandibular glands.

1980 • 474 citations

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1983 • 474 citations

The refined crystal structure of bovine β-trypsin at 1·8 Å resolution

1975 • 462 citations

Structure of a Mouse Submaxillary Messenger RNA Encoding Epidermal Growth Factor and Seven Related Proteins

1983 • 448 citations

Nerve Growth Factor from Mouse Submaxillary Gland: Amino Acid Sequence

1971 • 401 citations

The Isolation of the Mouse Nerve Growth Factor Protein in a High Molecular Weight Form^*

1967 • 372 citations

Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues.

1984 • 359 citations

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding

1978 • 301 citations

Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides

1983 • 295 citations

Nerve Growth Factor and Insulin

1972 • 283 citations

Kallikreins (kininogenases)--a group of serine proteases with bioregulatory actions.

1979 • 267 citations

Nerve Growth Factor

1978 • 243 citations

Refined 2 Å X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase

1983 • 224 citations

Isolation and characterization of renin-like enzymes from mouse submaxillary glands

1972 • 215 citations

Reversible dissociation of the mouse nerve growth factor protein into different subunits

1968 • 210 citations

Nerve growth factor

1974 • 207 citations

Refined 2.5 Å X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor

1983 • 199 citations

Guinea pig prostate is a rich source of nerve growth factor

1979 • 154 citations

Evidence for pro-β-nerve growth factor, a biosynthetic precursor to β-nerve growth factor

1977 • 153 citations

Methods for preparation of media, supplements, and substrata for serum-free animal cell culture

1984 • 146 citations

Two similar but nonallelic rat pancreatic trypsinogens. Nucleotide sequences of the cloned cDNAs.

1982 • 142 citations

Characterization of the Binding Protein for Epidermal Growth Factor

1974 • 131 citations

Proteolytic modification of the .beta. nerve growth factor protein

1974 • 120 citations

Subunit interaction and enzymic activity of mouse 7S nerve growth factor

1969 • 119 citations

The purification of nerve growth factor from bovine seminal plasma. Biochemical characterization and partial amino acid sequence.

1982 • 114 citations

Nerve Growth Factor

1977 • 113 citations

The amino acid sequence of the gamma-subunit of mouse submaxillary gland 7 S nerve growth factor.

1981 • 108 citations

Kallikrein-related mRNAs of the rat submaxillary gland: nucleotide sequences of four distinct types including tonin

1985 • 104 citations

Tissue-specific expression of kallikrein-related genes in the rat

1985 • 93 citations

Salivary Gland Hyperglycemic Factor: An Extrapancreatic Source of Glucagon-Like Material

1977 • 83 citations

Mouse glandular kallikrein genes. Nucleotide sequence of cloned cDNA coding for a member of the kallikrein arginyl esteropeptidase group of serine proteases.

1982 • 63 citations

Association of anhydrotrypsin with the pancreatic trypsin inhibitors

1974 • 57 citations

Isolation of a cDNA Clone Coding for the γ-Subunit of Mouse Nerve Growth Factor Using a High-Stringency Selection Procedure

1984 • 51 citations

Mouse 7S nerve growth factor: complete sequence of a cDNA coding for the .alpha.-subunit precursor and its relationship to serine proteases

1984 • 51 citations

Purification and properties of renin and gamma-renin from the mouse submaxillary gland.

1983 • 47 citations

The alpha-subunit of mouse 7 S nerve growth factor is an inactive serine protease.

1984 • 47 citations

Nerve growth factor synthesized by mouse fibroblast cells in culture: absence of .alpha. and .gamma. subunits

1983 • 38 citations

Nerve growth factor: Subunit interactions in the mouse submaxillary gland 7S complex

1982 • 37 citations

Use of a cDNA recombinant for the γ-subunit of mouse nerve growth factor to localize members of this multigene family near the TAM-1 locus on chromosome 7

1984 • 36 citations

Sequence of an epidermal growth factor-binding protein.

1984 • 35 citations

On the Hypothalamic Mechanism by Which Prostaglandin E<sub>2</sub> Stimulates Growth Hormone Release

1980 • 34 citations

Amino acid sequence of rat submaxillary tonin reveals similarities to serine proteases

1984 • 33 citations

Absence of the α and γ subunits of 7S nerve growth factor in denervated rodent iris: Immunocytochemical studies

1986 • 29 citations

7S Nerve growth factor .alpha. and .gamma. subunits are closely related proteins

1984 • 27 citations

Development of T lymphocytes in Xenopus laevis: Appearance of the antigen recognized by an anti-thymocyte mouse monoclonal antibody

1986 • 22 citations

Partial Amino‐Acid Sequence of the Epidermal Growth‐Factor‐Binding Protein

1982 • 20 citations

Nerve growth factor biosynthesis: Isolation and characterization of a guinea pig prostate kallikrein

1985 • 14 citations

Growth factor-binding proteases in the murine submaxillary gland: isolation of a cDNA clone.

1983 • 11 citations