Increased prostacyclin and thromboxane A2 biosynthesis in atherosclerosis.

Platelet Activation in Unstable Coronary Disease

1986 • 1,161 citations

Arachidonic Acid Metabolites and the Interactions between Platelets and Blood-Vessel Walls

1979 • 1,158 citations

Release of Prostaglandins and Thromboxane into the Coronary Circulation in Patients with Ischemic Heart Disease

1981 • 597 citations

Increased Prostacyclin Biosynthesis in Patients with Severe Atherosclerosis and Platelet Activation

1984 • 510 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Effect of Cholesterol on Production of Thromboxane B₂by Platelets in Vitro

1980 • 322 citations

Bovine endothelial cells in culture produce thromboxane as well as prostacyclin.

1981 • 300 citations

The generation of prostacyclin by arteries and by the coronary vascular bed is reduced in experimental atherosclerosis in rabbits

1977 • 287 citations

Alteration in the balance of prostaglandin and thromboxane synthesis in diabetic rats.

1980 • 183 citations

Cardiac and Coronary Prostaglandin Synthesis and Function

1978 • 160 citations

Prostacyclin and thromboxane A2 synthesis by rabbit pulmonary artery.

1980 • 117 citations

Prostacyclin production by cultured smooth muscle cells from atherosclerotic rabbit aorta

1980 • 96 citations

Role of stimulation of arachidonic acid release in the proliferative response of 3T3 mouse fibroblasts to platelet‐derived growth factor

1982 • 91 citations

Platelet function studies in coronary heart disease. IX. Increased platelet prostaglandin generation and abnormal platelet sensitivity to prostacyclin and endoperoxide analog in angina pectoris

1980 • 72 citations

Very low levels of 6-keto-prostaglandin F1 alpha in human plasma.

1982 • 69 citations

The significance of platelet-vessel wall prostaglandin equilibrium during exercise-induced stress

1983 • 64 citations

Human vascular tissues produce thromboxane as well as prostacyclin

1983 • 56 citations

Role of membrane lipid composition, organization, and fluidity in human platelet function.

1978 • 34 citations

Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits

1979 • 34 citations

Increased release of prostaglandins from the mesenteric vascular bed of diabetic animals: The effects of glucose and insulin

1986 • 32 citations

Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor oky 1581

1983 • 6 citations

Arachidonic acid and isolated human umbilical vein: Concentration-limited prostacyclin generation and absence of direct toxic effects on endothelial integrity

1985 • 5 citations