MUTATION LOAD AND THE SURVIVAL OF SMALL POPULATIONS

An introduction to population genetics theory

1970 • 4,120 citations

The Genetics and Biology of Drosophila

1978 • 3,910 citations

The Evolution of Sex

1978 • 3,074 citations

The relation of recombination to mutational advance

1964 • 2,547 citations

Genetics and Demography in Biological Conservation

1988 • 2,405 citations

THE EVOLUTIONARY ADVANTAGE OF RECOMBINATION

1974 • 1,737 citations

The Masterpiece of Nature: The Evolution and Genetics of Sexuality

1981 • 1,692 citations

Viable populations for conservation

1988 • 1,407 citations

Evolution of genes and proteins.

1983 • 1,224 citations

Deleterious mutations and the evolution of sexual reproduction

1988 • 1,130 citations

Statistical Properties of Segregating Sites

1995 • 959 citations

Our load of mutations.

1950 • 685 citations

Destabilizing Hybridization, General-Purpose Genotypes and Geographic Parthenogenesis

1984 • 646 citations

The Effect of Variation of Fitness

1937 • 631 citations

THE EVOLUTION OF SELF‐FERTILIZATION AND INBREEDING DEPRESSION IN PLANTS. II. EMPIRICAL OBSERVATIONS

1985 • 623 citations

Viable Populations for Conservation

1987 • 569 citations

Some Problems of Stochastic Processes in Genetics

1957 • 475 citations

Incomplete Forms of Influenza Virus

1954 • 371 citations

THE MUTATION LOAD IN SMALL POPULATIONS

1963 • 358 citations

The Species Problem

1974 • 243 citations

Phenotypic Evolution and Parthenogenesis

1983 • 207 citations

Cellular Senescence revisited: a review

1987 • 171 citations

Design and analysis of experiments on random drift and inbreeding depression.

1988 • 166 citations

Accumulation of mutations in sexual and asexual populations

1987 • 162 citations

Quantitative Genetic Variation

1980 • 151 citations

The Relation of Autoǵamy to Senescence and Rejuvenescence in Paramecium aurelia*

1954 • 139 citations

Genetic polymorphism and the role of mutation in evolution

1983 • 120 citations

The frequency distribution of lethal chromosomes in finite populations.

1968 • 117 citations

Evolution of sex in RNA viruses

1988 • 88 citations

Does Muller's ratchet work with selfing?

1978 • 86 citations

DNA Repair and Longevity Assurance in Paramecium tetraurelia

1979 • 76 citations

Aging and long-term temporal regulation in ciliated protozoa. A critical review

1974 • 74 citations

Intracellular determinants of cell aging

1984 • 73 citations

Recombination and the immortality of the germ line

1988 • 64 citations

Genetics and Aging in Protozoa

1981 • 55 citations

Colony size distribution as a measure of age in cultured human cells. A brief note

1977 • 47 citations

Clonal death associated with the number of fissions in Paramecium caudatum

1980 • 27 citations

Fifty years of genetic load

1987 • 25 citations

Ageing of hamster embryo fibroblasts as the result of both differentiation and stochastic mechanisms

1983 • 24 citations

Clonal aging in Paramecium tetraurelia. II. Evidence of functional changes in the macronucleus with age

1986 • 21 citations

POLYGENIC MUTATION

1979 • 20 citations

The effect of the reproductive system on mutation load

1988 • 19 citations

Germinal aging in Tetrahymena thermophila

1979 • 19 citations

Parthenogenetic populations can remain stable in spite of high mutation rate and random drift

1988 • 16 citations

The reproductive potential of normal mouse embryo fibroblasts during culture in vitro

1984 • 16 citations

Clonal aging in Paramecium tetraurelia, absence of evidence for a cytoplasmic factor

1984 • 15 citations

Clonal Attenuation In Chick Embryo Fibroblasts Experimental Data, A Model and Computer Simulations

1985 • 11 citations